CompoundList
Sign in
Murcko scaffold

2-[(3-Oxo-4-phenyl-3,4-dihydropyrazin-2-yl)sulfanyl]-N-phenylacetamide scaffold

355 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
355
With full pages
4
Scaffold SMILES

O=C(CSc1nccn(-c2ccccc2)c1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-[(3-Oxo-4-phenyl-3,4-dihydropyrazin-2-yl)sulfanyl]-N-phenylacetamide page
Murcko scaffold O=C(CSc1nccn(-c2ccccc2)c1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 355 chemicals

2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(2-methoxyphenyl)acetamide chemical structure, C21H21N3O3S, CAS 895108-23-3
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(2-methoxyphenyl)acetamide
CAS 895108-23-3C21H21N3O3S
N-(3,4-Dimethylphenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide chemical structure, C22H23N3O2S, CAS 895108-29-9
N-(3,4-Dimethylphenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide
CAS 895108-29-9C22H23N3O2S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-methoxyphenyl)acetamide chemical structure, C21H21N3O3S, CAS 895108-76-6
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-methoxyphenyl)acetamide
CAS 895108-76-6C21H21N3O3S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-fluorophenyl)acetamide chemical structure, C20H18FN3O2S, CAS 895108-82-4
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-fluorophenyl)acetamide
CAS 895108-82-4C20H18FN3O2S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(2-methylphenyl)acetamide chemical structure, C21H21N3O2S, CAS 895108-94-8
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(2-methylphenyl)acetamide
CAS 895108-94-8C21H21N3O2S
N-(3-Chlorophenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide chemical structure, C20H18ClN3O2S, CAS 895109-06-5
N-(3-Chlorophenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide
CAS 895109-06-5C20H18ClN3O2S
2-((4-(3,5-Dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)-N-mesitylacetamide chemical structure, C23H25N3O2S, CAS 895109-18-9
2-((4-(3,5-Dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)-N-mesitylacetamide
CAS 895109-18-9C23H25N3O2S
N-(2,4-Dimethylphenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide chemical structure, C22H23N3O2S, CAS 895109-30-5
N-(2,4-Dimethylphenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide
CAS 895109-30-5C22H23N3O2S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(2-fluorophenyl)acetamide chemical structure, C20H18FN3O2S, CAS 895109-42-9
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(2-fluorophenyl)acetamide
CAS 895109-42-9C20H18FN3O2S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-methyl-N-phenylacetamide chemical structure, C21H21N3O2S, CAS 895109-48-5
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-methyl-N-phenylacetamide
CAS 895109-48-5C21H21N3O2S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(3-fluoro-4-methylphenyl)acetamide chemical structure, C21H20FN3O2S, CAS 895109-60-1
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(3-fluoro-4-methylphenyl)acetamide
CAS 895109-60-1C21H20FN3O2S
N-(2,5-Dimethylphenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide chemical structure, C22H23N3O2S, CAS 895110-01-7
N-(2,5-Dimethylphenyl)-2-{[4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide
CAS 895110-01-7C22H23N3O2S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(3-methoxyphenyl)acetamide chemical structure, C21H21N3O3S, CAS 895107-93-4
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(3-methoxyphenyl)acetamide
CAS 895107-93-4C21H21N3O3S
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-propan-2-ylphenyl)acetamide chemical structure, C23H25N3O2S, CAS 895108-70-0
2-[4-(3,5-Dimethylphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-propan-2-ylphenyl)acetamide
CAS 895108-70-0C23H25N3O2S
2-{[4-(3,5-Dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}-N-phenylacetamide chemical structure, C20H19N3O2S, CAS 895109-77-0
2-{[4-(3,5-Dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}-N-phenylacetamide
CAS 895109-77-0C20H19N3O2S
N-(4-Chlorophenyl)-2-[4-(3,5-dimethylphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C20H18ClN3O2S, CAS 895109-95-2
N-(4-Chlorophenyl)-2-[4-(3,5-dimethylphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 895109-95-2C20H18ClN3O2S
2-[4-(4-Methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-methylphenyl)acetamide chemical structure, C20H19N3O3S, CAS 895111-39-4
2-[4-(4-Methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-methylphenyl)acetamide
CAS 895111-39-4C20H19N3O3S
N-(2-Methoxyphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C20H19N3O4S, CAS 895111-57-6
N-(2-Methoxyphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 895111-57-6C20H19N3O4S
N-(3,4-Dimethylphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C21H21N3O3S, CAS 895111-63-4
N-(3,4-Dimethylphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 895111-63-4C21H21N3O3S
N-(2-Ethylphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C21H21N3O3S, CAS 895111-75-8
N-(2-Ethylphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 895111-75-8C21H21N3O3S
2-[4-(4-Methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-propan-2-ylphenyl)acetamide chemical structure, C22H23N3O3S, CAS 895111-99-6
2-[4-(4-Methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(4-propan-2-ylphenyl)acetamide
CAS 895111-99-6C22H23N3O3S
N-(4-Methoxyphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide chemical structure, C20H19N3O4S, CAS 895112-05-7
N-(4-Methoxyphenyl)-2-[4-(4-methoxyphenyl)-3-oxopyrazin-2-yl]sulfanylacetamide
CAS 895112-05-7C20H19N3O4S
2-[4-(4-Methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(3-methylphenyl)acetamide chemical structure, C20H19N3O3S, CAS 895112-23-9
2-[4-(4-Methoxyphenyl)-3-oxopyrazin-2-yl]sulfanyl-N-(3-methylphenyl)acetamide
CAS 895112-23-9C20H19N3O3S
N-Mesityl-2-((4-(4-methoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide chemical structure, C22H23N3O3S, CAS 895112-35-3
N-Mesityl-2-((4-(4-methoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide
CAS 895112-35-3C22H23N3O3S