Murcko scaffold
2,4-Piperidinedione scaffold
92 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 8
- Chemicals
- 92
- With full pages
- 22
Scaffold SMILES
O=C1CCNC(=O)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 92 chemicals
Methyprylon
CAS 125-64-4C10H17NO2
3,3-Diethyl-2,4-piperidinedione
CAS 77-03-2C9H15NO2
N-Allylmethyprylon
CAS 106463-20-1C13H21NO2
6-(2-Methylpropyl)piperidine-2,4-dione
CAS 7230-10-6C9H15NO2
(2S)-4,6-Dioxopiperidine-2-carboxylic acid
CAS 872521-99-8C6H7NO4
Ethyl 2,4-dioxopiperidine-3-carboxylate
CAS 1026386-87-7C8H11NO4
2,4-Piperidinedione
CAS 50607-30-2C5H7NO2
Methyl 2,4-dioxopiperidine-3-carboxylate
CAS 74730-43-1C7H9NO4
6,6-Dimethylpiperidine-2,4-dione
CAS 5239-39-4C7H11NO2
Ethyl 1-Ethyl-2,4-dioxopiperidine-3-carboxylate
CAS 104966-05-4C10H15NO4
1-Ethylpiperidine-2,4-dione
CAS 99539-36-3C7H11NO2
1,5-Dimethyl-2,4-piperidinedione
CAS 115497-23-9C7H11NO2
3,3,5,5-Tetramethyl-2,4-piperidinedione
CAS 86096-15-3C9H15NO2
1,6,6-Trimethylpiperidine-2,4-dione
CAS 118263-86-8C8H13NO2
1,6-Dimethylpiperidine-2,4-dione
CAS 209901-13-3C7H11NO2
1,5,5-Trimethylpiperidine-2,4-dione
CAS 118263-85-7C8H13NO2
1-Isopropylpiperidine-2,4-dione
CAS 904301-91-3C8H13NO2
6-Methylpiperidine-2,4-dione
CAS 118263-99-3C6H9NO2
5-Methylpiperidine-2,4-dione
CAS 118263-96-0C6H9NO2
Methyl 6,6-dimethylpiperidine-2,4-dione-3-carboxylate
CAS 118263-88-0C9H13NO4
1-Methyl-2,4-piperidinedione
CAS 118263-97-1C6H9NO2
6-tert-Butylpiperidine-2,4-dione
CAS 2137581-82-7C9H15NO2
tert-Butyl 2,4-dioxopiperidine-1-carboxylate
CAS 845267-78-9C10H15NO4
Sodium 3-(methoxycarbonyl)-4-oxo-3,4,5,6-tetrahydro-2-pyridinolate
CAS 139122-78-4C7H8NNaO4
- tert-Butyl 2-isobutyl-4,6-dioxopiperidine-1-carboxylate942425-70-9C14H23NO4
- 5-Isopropylpiperidine-2,4-dione845267-70-1C8H13NO2
- 5-(2-Fluoroethyl)piperidine-2,4-dione942297-73-6C7H10FNO2
- tert-Butyl 4,6-dioxo-2-isopropylpiperidine-1-carboxylate1008510-48-2C13H21NO4
- 3-Piperidinecarboxylic acid, 6,6-dimethyl-2,4-dioxo-, ethyl ester845267-64-3C10H15NO4
- 5,5-Diethylpiperidine-2,4-dione845267-73-4C9H15NO2
- 5,5-Dimethylpiperidine-2,4-dione118263-81-3C7H11NO2
- tert-Butyl 4,6-dioxo-2-methylpiperidine-1-carboxylate1008510-46-0C11H17NO4
- 2,4-Dioxopiperidine-3-carboxylic acid220947-80-8C6H7NO4
- 3-Acetyl-6-methylpiperidine-2,4-dione127952-78-7C8H11NO3
- 3,3-Diethyl-1-propylpiperidine-2,4-dione698388-71-5C12H21NO2
- (6R)-6-(Propan-2-yl)piperidine-2,4-dione653589-25-4C8H13NO2
- 5-Ethylpiperidine-2,4-dione73290-32-1C7H11NO2
- Di-tert-butyl (2S)-4,6-dioxopiperidine-1,2-dicarboxylate653589-10-7C15H23NO6
- 6-Allyl-6-(fluoromethyl)piperidine-2,4-dione1228552-25-7C9H12FNO2
- 1-(tert-Butyl)piperidine-2,4-dione90608-67-6C9H15NO2
- 5,5-Difluoropiperidine-2,4-dione1258638-28-6C5H5F2NO2
- (S)-6-Methylpiperidine-2,4-dione653589-26-5C6H9NO2
- 3-Bromopiperidine-2,4-dione1271026-39-1C5H6BrNO2
- 3,3-Dimethylpiperidine-2,4-dione1824126-03-5C7H11NO2
- 6-(Chloromethyl)-6-(hydroxymethyl)-2,4-piperidinedione1105665-50-6C7H10ClNO3
- Methyl 6-(chloromethyl)-6-(hydroxymethyl)-2,4-dioxo-3-piperidinecarboxylate1105665-48-2C9H12ClNO5
- 3-Bromo-6,6-dimethyl-piperidine-2,4-dione1000801-14-8C7H10BrNO2
- Ethyl 1-Methyl-2,4-dioxopiperidine-3-carboxylate93758-44-2C9H13NO4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
