Murcko scaffold
Ring system with 2 rings and 21 atoms
56 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 21
- Chemicals
- 56
- With full pages
- 5
Scaffold SMILES
O=C(CNC(=O)OCc1ccccc1)Oc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 56 chemicals
N-((Phenylmethoxy)carbonyl)glycine 4-nitrophenyl ester
CAS 1738-86-9C16H14N2O6
![Pentachlorophenyl N-[[(4-methoxyphenyl)methoxy]carbonyl]-L-serinate chemical structure, C18H14Cl5NO6, CAS 23234-97-1](/s/UCEIZKVAZFNYMB-UHFFFAOYSA-N.svg)
Pentachlorophenyl N-[[(4-methoxyphenyl)methoxy]carbonyl]-L-serinate
CAS 23234-97-1C18H14Cl5NO6
(S)-4-Nitrophenyl 2-(((benzyloxy)carbonyl)amino)-4-methylpentanoate
CAS 1738-87-0C20H22N2O6
2,4,5-Trichlorophenyl N-((benzyloxy)carbonyl)-L-valinate
CAS 3065-23-4C19H18Cl3NO4
![4-Nitrophenyl N2-[(benzyloxy)carbonyl]-L-asparaginate chemical structure, C18H17N3O7, CAS 3256-57-3](/s/YLWIFNIVONXXMG-UHFFFAOYSA-N.svg)
4-Nitrophenyl N2-[(benzyloxy)carbonyl]-L-asparaginate
CAS 3256-57-3C18H17N3O7
N2-((Phenylmethoxy)carbonyl)-L-lysine 4-nitrophenyl ester
CAS 4272-71-3C20H23N3O6
Z-Gln-ONp
CAS 7763-16-8C19H19N3O7
Z-Val-ONp
CAS 10512-93-3C19H20N2O6
Perchlorophenyl N-(benzyloxycarbonyl)-L-isoleucinate
CAS 13673-53-5C20H18Cl5NO4
N2-Benzyl pentachlorophenyl N2-carboxy-L-(2-aminoglutaramate)
CAS 13673-51-3C19H15Cl5N2O5
2-Chloromethyl-4-nitrophenyl(N-carbobenzoxy)glycinate
CAS 52201-24-8C17H15ClN2O6
N(2)-benzyloxycarbonylarginine-4-nitrophenyl ester
CAS 68172-31-6C20H23N5O6
4-O-Methyl 1-O-(4-nitrophenyl) 2-(phenylmethoxycarbonylamino)butanedioate
CAS 3304-57-2C19H18N2O8
Carbobenzoxy-L-leucine p-nitrophenyl ester
CAS 4108-19-4C20H22N2O6
![2,4,5-Trichlorophenyl n-[(benzyloxy)carbonyl]alaninate chemical structure, C17H14Cl3NO4, CAS 7536-54-1](/s/ZNVWBEIILSUHOR-UHFFFAOYSA-N.svg)
2,4,5-Trichlorophenyl n-[(benzyloxy)carbonyl]alaninate
CAS 7536-54-1C17H14Cl3NO4
![4-Nitrophenyl N-[(benzyloxy)carbonyl]valinate chemical structure, C19H20N2O6, CAS 3411-74-3](/s/GLFONBITBIYJPS-UHFFFAOYSA-N.svg)
4-Nitrophenyl N-[(benzyloxy)carbonyl]valinate
CAS 3411-74-3C19H20N2O6
![2-Nitrophenyl N-[(benzyloxy)carbonyl]alaninate chemical structure, C17H16N2O6, CAS 40777-53-5](/s/KTBMOJNEQIETCR-UHFFFAOYSA-N.svg)
2-Nitrophenyl N-[(benzyloxy)carbonyl]alaninate
CAS 40777-53-5C17H16N2O6
![2-Nitrophenyl N-[(benzyloxy)carbonyl]glycinate chemical structure, C16H14N2O6, CAS 6154-41-2](/s/QLQCLAKOYRMJTG-UHFFFAOYSA-N.svg)
2-Nitrophenyl N-[(benzyloxy)carbonyl]glycinate
CAS 6154-41-2C16H14N2O6
![Pentachlorophenyl N-[(benzyloxy)carbonyl]glycinate chemical structure, C16H10Cl5NO4, CAS 4824-12-8](/s/RZCFLGRUTAWUCN-UHFFFAOYSA-N.svg)
Pentachlorophenyl N-[(benzyloxy)carbonyl]glycinate
CAS 4824-12-8C16H10Cl5NO4
![N-[(Phenylmethoxy)carbonyl]-L-isoleucine 4-nitrophenyl ester chemical structure, C20H22N2O6, CAS 2130-99-6](/s/NJDZCCJYUBNBMK-KSSFIOAISA-N.svg)
N-[(Phenylmethoxy)carbonyl]-L-isoleucine 4-nitrophenyl ester
CAS 2130-99-6C20H22N2O6
4-Nitrophenyl N2-((phenylmethoxy)carbonyl)lysinate monohydrochloride
CAS 2179-15-9C20H24ClN3O6
Z-D-Leu-ONp
CAS 52235-17-3C20H22N2O6
Z-D-Nle-ONp
CAS 31062-20-1C20H22N2O6
Z-L-Nle-ONp
CAS 24181-97-3C20H22N2O6
- Z-Ala-ONp1168-87-2C17H16N2O6
- (2,3,4,5,6-Pentachlorophenyl) (2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoate13758-71-9C20H18Cl5NO4
- (2,4,5-Trichlorophenyl) (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoateC19H18Cl3NO4
- Z-Lys(Boc)-ONp2212-69-3C25H31N3O8
- (2,3,4,5,6-Pentachlorophenyl) (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate13673-57-9C17H12Cl5NO5
- 4-Nitrophenyl (2S)-2-{[(benzyloxy)carbonyl]amino}-4-(methylsulfanyl)butanoate2483-42-3C19H20N2O6S
- (S)-4-tert-Butyl 1-(4-nitrophenyl) 2-(((benzyloxy)carbonyl)amino)succinate17543-17-8C22H24N2O8
- (R)-2-[(Benzyloxycarbonyl)amino]propanoic acid 4-nitrophenyl ester30960-00-0C17H16N2O6
- Z-Glu(otbu)-onp7670-08-8C23H26N2O8
- 4-Nitrophenyl N-[(benzyloxy)carbonyl]-L-serinate1676-91-1C17H16N2O7
- L-Arginine, N2-((phenylmethoxy)carbonyl)-, 2-nitrophenyl ester1330286-52-6C20H23N5O6
- 4-Nitrophenyl 2-{[(benzyloxy)carbonyl]amino}butanoate95632-85-2C18H18N2O6
- n2-[(Benzyloxy)carbonyl]-l-glutamine 2,4,5-trichlorophenyl ester39538-29-9C19H17Cl3N2O5
- (4-Nitrophenyl) (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate5545-50-6C21H24N2O7
- 4-Nitrophenyl N-[(benzyloxy)carbonyl]-L-norvalinate24178-79-8C19H20N2O6
- Z-D-Val-ONp10512-94-4C19H20N2O6
- 4-Nitrophenyl (2R)-2-{[(benzyloxy)carbonyl]amino}-3-carbamoylpropanoate2682-04-4C18H17N3O7
- D-Glutamine, N2-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester3196-71-2C19H19N3O7
- Z-D-Lys(Boc)-ONp50913-18-3C25H31N3O8
- 5-tert-Butyl 1-(2,4,5-trichlorophenyl) N-[(benzyloxy)carbonyl]-L-glutamate3405-82-1C23H24Cl3NO6
- 2,4,5-Trichlorophenyl N~2~-[(benzyloxy)carbonyl]-L-asparaginate2480-44-6C18H15Cl3N2O5
- N-[(Benzyloxy)carbonyl]-l-glutamic acid 5-methyl 1-(2,4,5-trichlorophenyl) ester39993-96-9C20H18Cl3NO6
- N-[(Benzyloxy)carbonyl]-l-glutamic acid 5-methyl 1-(pentachlorophenyl) ester25613-46-1C20H16Cl5NO6
- Z-Orn(Boc)-ONP7733-30-4C24H29N3O8
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CNC(=O)c1ccccc1)NN=Cc1ccccc1264 chemicals
c1ccc(CCCCNCCc2ccccc2)cc118 chemicals
O=C(NCCS(=O)(=O)NCc1ccccc1)c1ccccc117 chemicals
O=C(CCCCc1ccccc1)CCc1ccccc117 chemicals
c1ccc(OCCCCCOc2ccccc2)cc115 chemicals
c1ccc(CCCCCCCc2ccccc2)cc113 chemicals
O=C(NCCCNC(=O)c1ccccc1)c1ccccc111 chemicals
O=C(Cc1ccccc1)NCNC(=S)Nc1ccccc111 chemicals
O=C(C=Cc1ccccc1)CC(=O)C=Cc1ccccc111 chemicals
O=C(COC(=O)c1ccccc1)NCCC1=CCCCC110 chemicals
O=C(CC(=O)NCc1ccccc1)NCc1ccccc110 chemicals
O=C(COC(=O)c1cccnc1)NCCc1ccccc19 chemicals