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Murcko scaffold

2-(2-Thienyl)pyrimidine scaffold

215 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
215
With full pages
4
Scaffold SMILES

c1cnc(-c2cccs2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2-Thienyl)pyrimidine page
Murcko scaffold c1cnc(-c2cccs2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 215 chemicals

2-(2-Thienyl)pyrimidine chemical structure, C8H6N2S, CAS 56421-73-9
2-(2-Thienyl)pyrimidine
CAS 56421-73-9C8H6N2S
Ethyl 4-chloro-2-thien-2-ylpyrimidine-5-carboxylate chemical structure, C11H9ClN2O2S, CAS 188937-40-8
Ethyl 4-chloro-2-thien-2-ylpyrimidine-5-carboxylate
CAS 188937-40-8C11H9ClN2O2S
Ethyl 4-hydrazino-2-(2-thienyl)pyrimidine-5-carboxylate chemical structure, C11H12N4O2S, CAS 188937-42-0
Ethyl 4-hydrazino-2-(2-thienyl)pyrimidine-5-carboxylate
CAS 188937-42-0C11H12N4O2S
4,6-Dimethoxy-2-(thiophen-2-yl)pyrimidine chemical structure, C10H10N2O2S, CAS 402497-53-4
4,6-Dimethoxy-2-(thiophen-2-yl)pyrimidine
CAS 402497-53-4C10H10N2O2S
4,6-Dichloro-2-(2-thienyl)pyrimidine chemical structure, C8H4Cl2N2S, CAS 57059-13-9
4,6-Dichloro-2-(2-thienyl)pyrimidine
CAS 57059-13-9C8H4Cl2N2S
2-(4-Nitro-2-thienyl)pyrimidine chemical structure, C8H5N3O2S, CAS 57059-15-1
2-(4-Nitro-2-thienyl)pyrimidine
CAS 57059-15-1C8H5N3O2S
2-(5-Bromo-2-thienyl)pyrimidine chemical structure, C8H5BrN2S, CAS 65868-29-3
2-(5-Bromo-2-thienyl)pyrimidine
CAS 65868-29-3C8H5BrN2S
4-Chloro-2-(thiophen-2-yl)pyrimidine chemical structure, C8H5ClN2S, CAS 125904-07-6
4-Chloro-2-(thiophen-2-yl)pyrimidine
CAS 125904-07-6C8H5ClN2S
4-Hydrazinyl-2-(thiophen-2-yl)pyrimidine chemical structure, C8H8N4S, CAS 125926-68-3
4-Hydrazinyl-2-(thiophen-2-yl)pyrimidine
CAS 125926-68-3C8H8N4S
1-[4-Methyl-6-(methylsulfanyl)-2-(thiophen-2-yl)pyrimidin-5-yl]ethan-1-one chemical structure, C12H12N2OS2, CAS 189152-42-9
1-[4-Methyl-6-(methylsulfanyl)-2-(thiophen-2-yl)pyrimidin-5-yl]ethan-1-one
CAS 189152-42-9C12H12N2OS2
4-Methyl-6-(methylsulfanyl)-2-(thiophen-2-yl)pyrimidine-5-carboxylic acid chemical structure, C11H10N2O2S2, CAS 926249-08-3
4-Methyl-6-(methylsulfanyl)-2-(thiophen-2-yl)pyrimidine-5-carboxylic acid
CAS 926249-08-3C11H10N2O2S2
4,6-Dichloro-2-(5-methylthiophen-2-yl)pyrimidine chemical structure, C9H6Cl2N2S, CAS 89508-40-7
4,6-Dichloro-2-(5-methylthiophen-2-yl)pyrimidine
CAS 89508-40-7C9H6Cl2N2S
Ethyl 4-(methylamino)-2-(thiophen-2-yl)pyrimidine-5-carboxylate chemical structure, C12H13N3O2S, CAS 823794-77-0
Ethyl 4-(methylamino)-2-(thiophen-2-yl)pyrimidine-5-carboxylate
CAS 823794-77-0C12H13N3O2S
Ethyl 4-[amino(methyl)amino]-2-thiophen-2-ylpyrimidine-5-carboxylate chemical structure, C12H14N4O2S, CAS 188937-45-3
Ethyl 4-[amino(methyl)amino]-2-thiophen-2-ylpyrimidine-5-carboxylate
CAS 188937-45-3C12H14N4O2S
5-(Pyrimidin-2-yl)thiophene-2-carbaldehyde chemical structure, C9H6N2OS, CAS 545424-57-5
5-(Pyrimidin-2-yl)thiophene-2-carbaldehyde
CAS 545424-57-5C9H6N2OS
2-(Thiophen-2-yl)pyrimidine-5-carboxylic acid chemical structure, C9H6N2O2S, CAS 916766-97-7
2-(Thiophen-2-yl)pyrimidine-5-carboxylic acid
CAS 916766-97-7C9H6N2O2S
2-(Thiophen-2-yl)pyrimidine-5-carbonyl chloride chemical structure, C9H5ClN2OS, CAS 946409-25-2
2-(Thiophen-2-yl)pyrimidine-5-carbonyl chloride
CAS 946409-25-2C9H5ClN2OS
2-(Thiophen-2-yl)pyrimidine-5-carbaldehyde chemical structure, C9H6N2OS, CAS 921939-12-0
2-(Thiophen-2-yl)pyrimidine-5-carbaldehyde
CAS 921939-12-0C9H6N2OS
(2-Thien-2-ylpyrimidin-5-yl)methanol chemical structure, C9H8N2OS, CAS 921939-13-1
(2-Thien-2-ylpyrimidin-5-yl)methanol
CAS 921939-13-1C9H8N2OS
5-(Chloromethyl)-2-(thiophen-2-yl)pyrimidine chemical structure, C9H7ClN2S, CAS 926921-78-0
5-(Chloromethyl)-2-(thiophen-2-yl)pyrimidine
CAS 926921-78-0C9H7ClN2S
N-Methyl-(2-thien-2-ylpyrimidin-5-yl)methylamine chemical structure, C10H11N3S, CAS 921939-14-2
N-Methyl-(2-thien-2-ylpyrimidin-5-yl)methylamine
CAS 921939-14-2C10H11N3S
Ethyl 2-(thiophen-2-yl)pyrimidine-5-carboxylate chemical structure, C11H10N2O2S, CAS 954227-49-7
Ethyl 2-(thiophen-2-yl)pyrimidine-5-carboxylate
CAS 954227-49-7C11H10N2O2S
Ethyl 4-methyl-6-(methylsulfanyl)-2-(thiophen-2-yl)pyrimidine-5-carboxylate chemical structure, C13H14N2O2S2, CAS 1030222-82-2
Ethyl 4-methyl-6-(methylsulfanyl)-2-(thiophen-2-yl)pyrimidine-5-carboxylate
CAS 1030222-82-2C13H14N2O2S2
5-Pyrimidin-2-ylthiophene-2-carboxylic acid chemical structure, C9H6N2O2S, CAS 656226-79-8
5-Pyrimidin-2-ylthiophene-2-carboxylic acid
CAS 656226-79-8C9H6N2O2S