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Murcko scaffold

Ring system with 3 rings and 18 atoms

16 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 16
With full pages: 7

Scaffold SMILES

c1ccc(-c2nccc(-c3ccccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(-c2nccc(-c3ccccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-[4-(Pyridin-2-yl)pyrimidin-2-yl]phenol chemical structure, C15H11N3O, CAS 477856-93-2

4-[4-(Pyridin-2-yl)pyrimidin-2-yl]phenol

CAS 477856-93-2C₁₅H₁₁N₃O

Methyl 2-{4-[4-(2-pyridinyl)-2-pyrimidinyl]phenoxy}acetate chemical structure, C18H15N3O3, CAS 477857-18-4

Methyl 2-{4-[4-(2-pyridinyl)-2-pyrimidinyl]phenoxy}acetate

CAS 477857-18-4C₁₈H₁₅N₃O₃

2-{4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenoxy}acetic acid chemical structure, C17H13N3O3, CAS 477857-43-5

2-{4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenoxy}acetic acid

CAS 477857-43-5C₁₇H₁₃N₃O₃

2-{4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenoxy}acetohydrazide chemical structure, C17H15N5O2, CAS 477857-44-6

2-{4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenoxy}acetohydrazide

CAS 477857-44-6C₁₇H₁₅N₅O₂

Methyl 2-{4-[4-(2-pyridinyl)-2-pyrimidinyl]phenoxy}propanoate chemical structure, C19H17N3O3, CAS 477862-14-9

Methyl 2-{4-[4-(2-pyridinyl)-2-pyrimidinyl]phenoxy}propanoate

CAS 477862-14-9C₁₉H₁₇N₃O₃

2-{4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenoxy}propanohydrazide chemical structure, C18H17N5O2, CAS 477862-21-8

2-{4-[4-(2-Pyridinyl)-2-pyrimidinyl]phenoxy}propanohydrazide

CAS 477862-21-8C₁₈H₁₇N₅O₂

N-(3-Methoxypropyl)-2-{4-[4-(2-pyridinyl)-2-pyrimidinyl]phenoxy}acetamide chemical structure, C21H22N4O3, CAS 477870-56-7

N-(3-Methoxypropyl)-2-{4-[4-(2-pyridinyl)-2-pyrimidinyl]phenoxy}acetamide

CAS 477870-56-7C₂₁H₂₂N₄O₃

3-Fluoropropyl 4-[4-(2-pyridinyl)-2-pyrimidinyl]phenyl ether chemical structure, C18H16FN3O, CAS 477862-13-8

3-Fluoropropyl 4-[4-(2-pyridinyl)-2-pyrimidinyl]phenyl ether

CAS 477862-13-8C₁₈H₁₆FN₃O

4-(Methylsulfanyl)-2-phenyl-6-(pyridin-2-yl)pyrimidine chemical structure, C16H13N3S, CAS 87568-80-7

4-(Methylsulfanyl)-2-phenyl-6-(pyridin-2-yl)pyrimidine

CAS 87568-80-7C₁₆H₁₃N₃S

4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylpyrimidine chemical structure, C16H9ClF3N3, CAS 1092344-48-3

4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylpyrimidine

CAS 1092344-48-3C₁₆H₉ClF₃N₃

4-Chloro-2-phenyl-6-(pyridin-2-yl)pyrimidine chemical structure, C15H10ClN3, CAS 350490-71-0

4-Chloro-2-phenyl-6-(pyridin-2-yl)pyrimidine

CAS 350490-71-0C₁₅H₁₀ClN₃

4-Amino-2-phenyl-6-(2-pyridyl)pyrimidine chemical structure, C15H12N4, CAS 1159819-31-4

4-Amino-2-phenyl-6-(2-pyridyl)pyrimidine

CAS 1159819-31-4C₁₅H₁₂N₄

2-Phenyl-6-(pyridin-2-yl)pyrimidine-4-carbaldehyde chemical structure, C16H11N3O, CAS 922726-32-7

2-Phenyl-6-(pyridin-2-yl)pyrimidine-4-carbaldehyde

CAS 922726-32-7C₁₆H₁₁N₃O

(2-Phenyl-6-(pyridin-2-yl)pyrimidin-4-yl)methanol chemical structure, C16H13N3O, CAS 922726-29-2

(2-Phenyl-6-(pyridin-2-yl)pyrimidin-4-yl)methanol

CAS 922726-29-2C₁₆H₁₃N₃O

4-(Methoxymethyl)-2-phenyl-6-(pyridin-2-yl)pyrimidine chemical structure, C17H15N3O, CAS 922726-27-0

4-(Methoxymethyl)-2-phenyl-6-(pyridin-2-yl)pyrimidine

CAS 922726-27-0C₁₇H₁₅N₃O

4-Bromo-2-phenyl-6-pyridin-2-ylpyrimidine chemical structure, C15H10BrN3, CAS 1818435-91-4

4-Bromo-2-phenyl-6-pyridin-2-ylpyrimidine

CAS 1818435-91-4C₁₅H₁₀BrN₃