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Murcko scaffold

3-Phenylimidazolidine-2,4-dione scaffold

239 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
239
With full pages
18
Scaffold SMILES

O=C1CNC(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylimidazolidine-2,4-dione page
Murcko scaffold O=C1CNC(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 239 chemicals

Nilutamide chemical structure, C12H10F3N3O4, CAS 63612-50-0
Nilutamide
CAS 63612-50-0C12H10F3N3O4
Iprodione chemical structure, C13H13Cl2N3O3, CAS 36734-19-7
Iprodione
CAS 36734-19-7C13H13Cl2N3O3
Hydantoin, 3-(o-chlorophenyl)-5,5-dimethyl- chemical structure, C11H11ClN2O2, CAS 51027-22-6
Hydantoin, 3-(o-chlorophenyl)-5,5-dimethyl-
CAS 51027-22-6C11H11ClN2O2
Hydantoin, 3-(p-chlorophenyl)-5-methyl- chemical structure, C10H9ClN2O2, CAS 56012-09-0
Hydantoin, 3-(p-chlorophenyl)-5-methyl-
CAS 56012-09-0C10H9ClN2O2
3-(4-Chlorophenyl)-2-hydroxy-5,5-dimethyl-3,5-dihydro-4H-imidazol-4-one chemical structure, C11H11ClN2O2, CAS 70974-23-1
3-(4-Chlorophenyl)-2-hydroxy-5,5-dimethyl-3,5-dihydro-4H-imidazol-4-one
CAS 70974-23-1C11H11ClN2O2
Hydantoin, 5-(2-methylthioethyl)-3-phenyl- chemical structure, C12H14N2O2S, CAS 24631-46-7
Hydantoin, 5-(2-methylthioethyl)-3-phenyl-
CAS 24631-46-7C12H14N2O2S
5,5-Dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin chemical structure, C12H10F4N2O2, CAS 70842-04-5
5,5-Dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin
CAS 70842-04-5C12H10F4N2O2
4-(3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile chemical structure, C17H18F3N3O3, CAS 154992-24-2
4-(3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile
CAS 154992-24-2C17H18F3N3O3
Desisopropyliprodione chemical structure, C10H7Cl2N3O3, CAS 79076-80-5
Desisopropyliprodione
CAS 79076-80-5C10H7Cl2N3O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(3-methyl-1-oxo-2-butenyl)- chemical structure, C14H12Cl2N2O3, CAS 67851-39-2
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(3-methyl-1-oxo-2-butenyl)-
CAS 67851-39-2C14H12Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(1-oxo-2-propenyl)- chemical structure, C12H8Cl2N2O3, CAS 67851-36-9
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(1-oxo-2-propenyl)-
CAS 67851-36-9C12H8Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-methyl-1-oxopropyl)- chemical structure, C13H12Cl2N2O3, CAS 70017-92-4
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-methyl-1-oxopropyl)-
CAS 70017-92-4C13H12Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(methoxyacetyl)- chemical structure, C12H10Cl2N2O4, CAS 70142-02-8
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(methoxyacetyl)-
CAS 70142-02-8C12H10Cl2N2O4
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(ethoxyacetyl)- chemical structure, C13H12Cl2N2O4, CAS 69908-50-5
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(ethoxyacetyl)-
CAS 69908-50-5C13H12Cl2N2O4
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-((1-methylethoxy)acetyl)- chemical structure, C14H14Cl2N2O4, CAS 69908-55-0
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-((1-methylethoxy)acetyl)-
CAS 69908-55-0C14H14Cl2N2O4
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-ethoxy-1-oxopropyl)- chemical structure, C14H14Cl2N2O4, CAS 69908-56-1
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-ethoxy-1-oxopropyl)-
CAS 69908-56-1C14H14Cl2N2O4
Isovaledione chemical structure, C14H14Cl2N2O3, CAS 70017-93-5
Isovaledione
CAS 70017-93-5C14H14Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2,2-dimethyl-1-oxopropyl)- chemical structure, C14H14Cl2N2O3, CAS 70017-94-6
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2,2-dimethyl-1-oxopropyl)-
CAS 70017-94-6C14H14Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(3,3-dimethyl-1-oxobutyl)- chemical structure, C15H16Cl2N2O3, CAS 70017-95-7
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(3,3-dimethyl-1-oxobutyl)-
CAS 70017-95-7C15H16Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-methyl-1-oxobutyl)- chemical structure, C14H14Cl2N2O3, CAS 70017-97-9
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-methyl-1-oxobutyl)-
CAS 70017-97-9C14H14Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(3-methyl-1-oxopentyl)- chemical structure, C15H16Cl2N2O3, CAS 70017-98-0
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(3-methyl-1-oxopentyl)-
CAS 70017-98-0C15H16Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-ethyl-1-oxobutyl)- chemical structure, C15H16Cl2N2O3, CAS 70017-99-1
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(2-ethyl-1-oxobutyl)-
CAS 70017-99-1C15H16Cl2N2O3
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(4-methyl-1-oxopentyl)- chemical structure, C15H16Cl2N2O3, CAS 70018-01-8
2,4-Imidazolidinedione, 3-(3,5-dichlorophenyl)-1-(4-methyl-1-oxopentyl)-
CAS 70018-01-8C15H16Cl2N2O3
3-(3,5-Dichlorophenyl)-2,4-imidazolidinedione chemical structure, C9H6Cl2N2O2, CAS 27387-87-7
3-(3,5-Dichlorophenyl)-2,4-imidazolidinedione
CAS 27387-87-7C9H6Cl2N2O2