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Murcko scaffold

2-Hydroxy-5-phenylpyridine scaffold

776 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
776
With full pages
32
Scaffold SMILES

O=c1ccc(-c2ccccc2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-5-phenylpyridine page
Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 433 to 480 of 776 chemicals

2-Hydroxy-5-(4-methylsulfonylphenyl)isonicotinic acid chemical structure, C13H11NO5S, CAS 1261965-81-4
2-Hydroxy-5-(4-methylsulfonylphenyl)isonicotinic acid
CAS 1261965-81-4C13H11NO5S
5-(2-Chloro-4-ethoxyphenyl)-2-hydroxynicotinic acid chemical structure, C14H12ClNO4, CAS 1261934-96-6
5-(2-Chloro-4-ethoxyphenyl)-2-hydroxynicotinic acid
CAS 1261934-96-6C14H12ClNO4
5-(2-Chloro-4-ethoxyphenyl)-2-hydroxyisonicotinic acid chemical structure, C14H12ClNO4, CAS 1261888-61-2
5-(2-Chloro-4-ethoxyphenyl)-2-hydroxyisonicotinic acid
CAS 1261888-61-2C14H12ClNO4
5-(3-Carboxy-4-chlorophenyl)-2-hydroxynicotinic acid chemical structure, C13H8ClNO5, CAS 1261888-64-5
5-(3-Carboxy-4-chlorophenyl)-2-hydroxynicotinic acid
CAS 1261888-64-5C13H8ClNO5
5-(3-Carboxy-4-chlorophenyl)-2-hydroxyisonicotinic acid chemical structure, C13H8ClNO5, CAS 1261933-46-3
5-(3-Carboxy-4-chlorophenyl)-2-hydroxyisonicotinic acid
CAS 1261933-46-3C13H8ClNO5
2-Hydroxy-5-(3-trifluoromethoxyphenyl)nicotinic acid chemical structure, C13H8F3NO4, CAS 1261729-32-1
2-Hydroxy-5-(3-trifluoromethoxyphenyl)nicotinic acid
CAS 1261729-32-1C13H8F3NO4
2-Hydroxy-5-(3-trifluoromethoxyphenyl)isonicotinic acid chemical structure, C13H8F3NO4, CAS 1261839-27-3
2-Hydroxy-5-(3-trifluoromethoxyphenyl)isonicotinic acid
CAS 1261839-27-3C13H8F3NO4
2-Hydroxy-5-(4-trifluoromethoxyphenyl)nicotinic acid chemical structure, C13H8F3NO4, CAS 1261740-19-5
2-Hydroxy-5-(4-trifluoromethoxyphenyl)nicotinic acid
CAS 1261740-19-5C13H8F3NO4
2-Hydroxy-5-(4-trifluoromethoxyphenyl)isonicotinic acid chemical structure, C13H8F3NO4, CAS 1261729-22-9
2-Hydroxy-5-(4-trifluoromethoxyphenyl)isonicotinic acid
CAS 1261729-22-9C13H8F3NO4
5-(2-Fluoro-3-trifluoromethylphenyl)-2-hydroxynicotinic acid chemical structure, C13H7F4NO3, CAS 1261888-72-5
5-(2-Fluoro-3-trifluoromethylphenyl)-2-hydroxynicotinic acid
CAS 1261888-72-5C13H7F4NO3
5-(2-Fluoro-3-trifluoromethylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H7F4NO3, CAS 1261920-39-1
5-(2-Fluoro-3-trifluoromethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261920-39-1C13H7F4NO3
5-(4-Fluoro-3-trifluoromethylphenyl)-2-hydroxynicotinic acid chemical structure, C13H7F4NO3, CAS 1261908-34-2
5-(4-Fluoro-3-trifluoromethylphenyl)-2-hydroxynicotinic acid
CAS 1261908-34-2C13H7F4NO3
5-(4-Fluoro-3-trifluoromethylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H7F4NO3, CAS 1261920-47-1
5-(4-Fluoro-3-trifluoromethylphenyl)-2-hydroxyisonicotinic acid
CAS 1261920-47-1C13H7F4NO3
5-(3,5-Dicarboxyphenyl)-2-hydroxynicotinic acid chemical structure, C14H9NO7, CAS 1262008-97-8
5-(3,5-Dicarboxyphenyl)-2-hydroxynicotinic acid
CAS 1262008-97-8C14H9NO7
5-(3,5-Dicarboxyphenyl)-2-hydroxyisonicotinic acid chemical structure, C14H9NO7, CAS 1261935-52-7
5-(3,5-Dicarboxyphenyl)-2-hydroxyisonicotinic acid
CAS 1261935-52-7C14H9NO7
5-[4-(Ethylcarbamoyl)-3-fluorophenyl]-2-hydroxynicotinic acid chemical structure, C15H13FN2O4, CAS 1261966-75-9
5-[4-(Ethylcarbamoyl)-3-fluorophenyl]-2-hydroxynicotinic acid
CAS 1261966-75-9C15H13FN2O4
5-[4-(Ethylcarbamoyl)-3-fluorophenyl]-2-hydroxyisonicotinic acid chemical structure, C15H13FN2O4, CAS 1261920-63-1
5-[4-(Ethylcarbamoyl)-3-fluorophenyl]-2-hydroxyisonicotinic acid
CAS 1261920-63-1C15H13FN2O4
5-[4-(Ethoxycarbonyl)-3-fluorophenyl]-2-hydroxynicotinic acid chemical structure, C15H12FNO5, CAS 1262005-23-1
5-[4-(Ethoxycarbonyl)-3-fluorophenyl]-2-hydroxynicotinic acid
CAS 1262005-23-1C15H12FNO5
5-[4-(Ethoxycarbonyl)-3-fluorophenyl]-2-hydroxyisonicotinic acid chemical structure, C15H12FNO5, CAS 1261920-87-9
5-[4-(Ethoxycarbonyl)-3-fluorophenyl]-2-hydroxyisonicotinic acid
CAS 1261920-87-9C15H12FNO5
5-(2-Chloro-5-methoxycarbonylphenyl)-2-hydroxynicotinic acid chemical structure, C14H10ClNO5, CAS 1261938-27-5
5-(2-Chloro-5-methoxycarbonylphenyl)-2-hydroxynicotinic acid
CAS 1261938-27-5C14H10ClNO5
5-(2-Chloro-5-methoxycarbonylphenyl)-2-hydroxyisonicotinic acid chemical structure, C14H10ClNO5, CAS 1261957-94-1
5-(2-Chloro-5-methoxycarbonylphenyl)-2-hydroxyisonicotinic acid
CAS 1261957-94-1C14H10ClNO5
5-(3-Chloro-4-methoxycarbonylphenyl)-2-hydroxynicotinic acid chemical structure, C14H10ClNO5, CAS 1261975-81-8
5-(3-Chloro-4-methoxycarbonylphenyl)-2-hydroxynicotinic acid
CAS 1261975-81-8C14H10ClNO5
5-(3-Chloro-4-methoxycarbonylphenyl)-2-hydroxyisonicotinic acid chemical structure, C14H10ClNO5, CAS 1261972-44-4
5-(3-Chloro-4-methoxycarbonylphenyl)-2-hydroxyisonicotinic acid
CAS 1261972-44-4C14H10ClNO5
5-(4-Chloro-3-methoxycarbonylphenyl)-2-hydroxynicotinic acid chemical structure, C14H10ClNO5, CAS 1262009-61-9
5-(4-Chloro-3-methoxycarbonylphenyl)-2-hydroxynicotinic acid
CAS 1262009-61-9C14H10ClNO5