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Murcko scaffold

2-Hydroxy-5-phenylpyridine scaffold

776 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
776
With full pages
32
Scaffold SMILES

O=c1ccc(-c2ccccc2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-5-phenylpyridine page
Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 384 of 776 chemicals

5-(5-Fluoro-2-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C13H10FNO4, CAS 1261923-19-6
5-(5-Fluoro-2-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 1261923-19-6C13H10FNO4
5-(5-Fluoro-2-methoxyphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10FNO4, CAS 1261923-15-2
5-(5-Fluoro-2-methoxyphenyl)-2-hydroxyisonicotinic acid
CAS 1261923-15-2C13H10FNO4
5-(2-Chloro-4-methylphenyl)-2-hydroxynicotinic acid chemical structure, C13H10ClNO3, CAS 1262005-92-4
5-(2-Chloro-4-methylphenyl)-2-hydroxynicotinic acid
CAS 1262005-92-4C13H10ClNO3
5-(2-Chloro-4-methylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10ClNO3, CAS 1261932-55-1
5-(2-Chloro-4-methylphenyl)-2-hydroxyisonicotinic acid
CAS 1261932-55-1C13H10ClNO3
5-(3-Chloro-2-methylphenyl)-2-hydroxynicotinic acid chemical structure, C13H10ClNO3, CAS 1261904-37-3
5-(3-Chloro-2-methylphenyl)-2-hydroxynicotinic acid
CAS 1261904-37-3C13H10ClNO3
5-(3-Chloro-2-methylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10ClNO3, CAS 1261982-70-0
5-(3-Chloro-2-methylphenyl)-2-hydroxyisonicotinic acid
CAS 1261982-70-0C13H10ClNO3
5-(3-Chloro-4-methylphenyl)-2-hydroxynicotinic acid chemical structure, C13H10ClNO3, CAS 1261983-45-2
5-(3-Chloro-4-methylphenyl)-2-hydroxynicotinic acid
CAS 1261983-45-2C13H10ClNO3
5-(3-Chloro-4-methylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10ClNO3, CAS 1261923-57-2
5-(3-Chloro-4-methylphenyl)-2-hydroxyisonicotinic acid
CAS 1261923-57-2C13H10ClNO3
5-(3-Chloro-5-methylphenyl)-2-hydroxynicotinic acid chemical structure, C13H10ClNO3, CAS 1261909-43-6
5-(3-Chloro-5-methylphenyl)-2-hydroxynicotinic acid
CAS 1261909-43-6C13H10ClNO3
5-(3-Chloro-5-methylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10ClNO3, CAS 1261904-69-1
5-(3-Chloro-5-methylphenyl)-2-hydroxyisonicotinic acid
CAS 1261904-69-1C13H10ClNO3
5-(4-Chloro-2-methylphenyl)-2-hydroxynicotinic acid chemical structure, C13H10ClNO3, CAS 1261932-63-1
5-(4-Chloro-2-methylphenyl)-2-hydroxynicotinic acid
CAS 1261932-63-1C13H10ClNO3
5-(4-Chloro-2-methylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10ClNO3, CAS 1262006-26-7
5-(4-Chloro-2-methylphenyl)-2-hydroxyisonicotinic acid
CAS 1262006-26-7C13H10ClNO3
5-(4-Chloro-3-methylphenyl)-2-hydroxynicotinic acid chemical structure, C13H10ClNO3, CAS 1261984-29-5
5-(4-Chloro-3-methylphenyl)-2-hydroxynicotinic acid
CAS 1261984-29-5C13H10ClNO3
5-(4-Chloro-3-methylphenyl)-2-hydroxyisonicotinic acid chemical structure, C13H10ClNO3, CAS 1261993-91-2
5-(4-Chloro-3-methylphenyl)-2-hydroxyisonicotinic acid
CAS 1261993-91-2C13H10ClNO3
5-(2-Chloro-5-hydroxyphenyl)-2-hydroxynicotinic acid chemical structure, C12H8ClNO4, CAS 1261964-64-0
5-(2-Chloro-5-hydroxyphenyl)-2-hydroxynicotinic acid
CAS 1261964-64-0C12H8ClNO4
5-(2-Chloro-5-hydroxyphenyl)-2-hydroxyisonicotinic acid chemical structure, C12H8ClNO4, CAS 1261962-29-1
5-(2-Chloro-5-hydroxyphenyl)-2-hydroxyisonicotinic acid
CAS 1261962-29-1C12H8ClNO4
5-(3-Chloro-5-fluorophenyl)-2-hydroxynicotinic acid chemical structure, C12H7ClFNO3, CAS 1261909-82-3
5-(3-Chloro-5-fluorophenyl)-2-hydroxynicotinic acid
CAS 1261909-82-3C12H7ClFNO3
5-(3-Chloro-5-fluorophenyl)-2-hydroxyisonicotinic acid chemical structure, C12H7ClFNO3, CAS 1261921-81-6
5-(3-Chloro-5-fluorophenyl)-2-hydroxyisonicotinic acid
CAS 1261921-81-6C12H7ClFNO3
5-(3-Chloro-4-fluorophenyl)-2-hydroxynicotinic acid chemical structure, C12H7ClFNO3, CAS 1261950-09-7
5-(3-Chloro-4-fluorophenyl)-2-hydroxynicotinic acid
CAS 1261950-09-7C12H7ClFNO3
5-(3-Chloro-4-fluorophenyl)-2-hydroxyisonicotinic acid chemical structure, C12H7ClFNO3, CAS 1261909-86-7
5-(3-Chloro-4-fluorophenyl)-2-hydroxyisonicotinic acid
CAS 1261909-86-7C12H7ClFNO3
2-Hydroxy-5-(2,4,6-trifluorophenyl)nicotinic acid chemical structure, C12H6F3NO3, CAS 1261922-40-0
2-Hydroxy-5-(2,4,6-trifluorophenyl)nicotinic acid
CAS 1261922-40-0C12H6F3NO3
2-Hydroxy-5-(2,4,6-trifluorophenyl)isonicotinic acid chemical structure, C12H6F3NO3, CAS 1261950-18-8
2-Hydroxy-5-(2,4,6-trifluorophenyl)isonicotinic acid
CAS 1261950-18-8C12H6F3NO3
2-Hydroxy-5-(4-T-butylphenyl)nicotinic acid chemical structure, C16H17NO3, CAS 1261904-88-4
2-Hydroxy-5-(4-T-butylphenyl)nicotinic acid
CAS 1261904-88-4C16H17NO3
2-Hydroxy-5-(4-T-butylphenyl)isonicotinic acid chemical structure, C16H17NO3, CAS 1261954-99-7
2-Hydroxy-5-(4-T-butylphenyl)isonicotinic acid
CAS 1261954-99-7C16H17NO3