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Murcko scaffold

2-Hydroxy-5-phenylpyridine scaffold

776 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 13
Chemicals: 776
With full pages: 32

Scaffold SMILES

O=c1ccc(-c2ccccc2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-Hydroxy-5-phenylpyridine page

Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 529 to 576 of 776 chemicals

5-(3-Methoxyphenyl)-3-methylpyridin-2-ol chemical structure, C13H13NO2, CAS 1553106-34-5

5-(3-Methoxyphenyl)-3-methylpyridin-2-ol

CAS 1553106-34-5C₁₃H₁₃NO₂

3-Methyl-5-(m-tolyl)pyridin-2-ol chemical structure, C13H13NO, CAS 1553106-39-0

3-Methyl-5-(m-tolyl)pyridin-2-ol

CAS 1553106-39-0C₁₃H₁₃NO

5-(2,5-Difluorophenyl)-3-methylpyridin-2-ol chemical structure, C12H9F2NO, CAS 1555362-56-5

5-(2,5-Difluorophenyl)-3-methylpyridin-2-ol

CAS 1555362-56-5C₁₂H₉F₂NO

5-(2,4-Dimethylphenyl)-3-methylpyridin-2-ol chemical structure, C14H15NO, CAS 1546291-83-1

5-(2,4-Dimethylphenyl)-3-methylpyridin-2-ol

CAS 1546291-83-1C₁₄H₁₅NO

5-(2,4-Dichlorophenyl)-3-methylpyridin-2-ol chemical structure, C12H9Cl2NO, CAS 1361814-41-6

5-(2,4-Dichlorophenyl)-3-methylpyridin-2-ol

CAS 1361814-41-6C₁₂H₉Cl₂NO

5-(3,5-Dinitrophenyl)-1-methyl-2(1H)-pyridinone chemical structure, C12H9N3O5, CAS 1036755-90-4

5-(3,5-Dinitrophenyl)-1-methyl-2(1H)-pyridinone

CAS 1036755-90-4C₁₂H₉N₃O₅

5-(3-Methoxy-4-methylphenyl)pyridin-2-ol chemical structure, C13H13NO2, CAS 1111103-42-4

5-(3-Methoxy-4-methylphenyl)pyridin-2-ol

CAS 1111103-42-4C₁₃H₁₃NO₂

3-(Hydroxymethyl)-5-phenylpyridin-2-ol chemical structure, C12H11NO2, CAS 1227591-01-6

3-(Hydroxymethyl)-5-phenylpyridin-2-ol

CAS 1227591-01-6C₁₂H₁₁NO₂

3-Hexanoyl-4-Hydroxy-5-(4-Hydroxyphenyl)pyridin-2(1H)-One chemical structure, C17H19NO4, CAS 1774346-60-9

3-Hexanoyl-4-Hydroxy-5-(4-Hydroxyphenyl)pyridin-2(1H)-One

CAS 1774346-60-9C₁₇H₁₉NO₄

3-[(2E,4E)-4,6-Dimethylocta-2,4-dienoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1H-pyridin-2-one chemical structure, C21H23NO4, CAS 1094390-39-2

3-[(2E,4E)-4,6-Dimethylocta-2,4-dienoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1H-pyridin-2-one

CAS 1094390-39-2C₂₁H₂₃NO₄

3-Amino-1-methyl-5-(2-(trifluoromethyl)phenyl)pyridin-2(1H)-one chemical structure, C13H11F3N2O, CAS 1891097-27-0

3-Amino-1-methyl-5-(2-(trifluoromethyl)phenyl)pyridin-2(1H)-one

CAS 1891097-27-0C₁₃H₁₁F₃N₂O

3-Amino-1-methyl-5-(o-tolyl)pyridin-2(1H)-one chemical structure, C13H14N2O, CAS 1894733-98-2

3-Amino-1-methyl-5-(o-tolyl)pyridin-2(1H)-one

CAS 1894733-98-2C₁₃H₁₄N₂O

3-Amino-5-(2-fluorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11FN2O, CAS 1894404-76-2

3-Amino-5-(2-fluorophenyl)-1-methylpyridin-2(1H)-one

CAS 1894404-76-2C₁₂H₁₁FN₂O

3-Amino-5-(2-chlorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11ClN2O, CAS 1894101-08-6

3-Amino-5-(2-chlorophenyl)-1-methylpyridin-2(1H)-one

CAS 1894101-08-6C₁₂H₁₁ClN₂O

3-Pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-5-phenyl- chemical structure, C13H11NO3, CAS 1891342-38-3

3-Pyridinecarboxylic acid, 1,2-dihydro-1-methyl-2-oxo-5-phenyl-

CAS 1891342-38-3C₁₃H₁₁NO₃

3-Amino-1-methyl-5-(3-(trifluoromethyl)phenyl)pyridin-2(1H)-one chemical structure, C13H11F3N2O, CAS 1894377-56-0

3-Amino-1-methyl-5-(3-(trifluoromethyl)phenyl)pyridin-2(1H)-one

CAS 1894377-56-0C₁₃H₁₁F₃N₂O

3-Amino-1-methyl-5-(m-tolyl)pyridin-2(1H)-one chemical structure, C13H14N2O, CAS 1891150-27-8

3-Amino-1-methyl-5-(m-tolyl)pyridin-2(1H)-one

CAS 1891150-27-8C₁₃H₁₄N₂O

3-Amino-5-(3-fluorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11FN2O, CAS 1894677-28-1

3-Amino-5-(3-fluorophenyl)-1-methylpyridin-2(1H)-one

CAS 1894677-28-1C₁₂H₁₁FN₂O

3-Amino-5-(3-chlorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11ClN2O, CAS 1894485-26-7

3-Amino-5-(3-chlorophenyl)-1-methylpyridin-2(1H)-one

CAS 1894485-26-7C₁₂H₁₁ClN₂O

3-Amino-5-(3-methoxyphenyl)-1-methylpyridin-2(1H)-one chemical structure, C13H14N2O2, CAS 1894948-69-6

3-Amino-5-(3-methoxyphenyl)-1-methylpyridin-2(1H)-one

CAS 1894948-69-6C₁₃H₁₄N₂O₂

3-Amino-1-methyl-5-(4-(trifluoromethyl)phenyl)pyridin-2(1H)-one chemical structure, C13H11F3N2O, CAS 1890638-88-6

3-Amino-1-methyl-5-(4-(trifluoromethyl)phenyl)pyridin-2(1H)-one

CAS 1890638-88-6C₁₃H₁₁F₃N₂O

3-Amino-1-methyl-5-(p-tolyl)pyridin-2(1H)-one chemical structure, C13H14N2O, CAS 1891330-63-4

3-Amino-1-methyl-5-(p-tolyl)pyridin-2(1H)-one

CAS 1891330-63-4C₁₃H₁₄N₂O

3-Amino-5-(4-fluorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11FN2O, CAS 1896112-19-8

3-Amino-5-(4-fluorophenyl)-1-methylpyridin-2(1H)-one

CAS 1896112-19-8C₁₂H₁₁FN₂O

3-Amino-5-(4-chlorophenyl)-1-methylpyridin-2(1H)-one chemical structure, C12H11ClN2O, CAS 1894485-30-3

3-Amino-5-(4-chlorophenyl)-1-methylpyridin-2(1H)-one

CAS 1894485-30-3C₁₂H₁₁ClN₂O