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Murcko scaffold

2-Hydroxy-5-phenylpyridine scaffold

776 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
776
With full pages
32
Scaffold SMILES

O=c1ccc(-c2ccccc2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-5-phenylpyridine page
Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 577 to 624 of 776 chemicals

5-[4-[(Dimethylamino)methyl]phenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C16H20N2O, CAS 1883429-24-0
5-[4-[(Dimethylamino)methyl]phenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 1883429-24-0C16H20N2O
5-[4-[(Dimethylamino)methyl]-3-methoxyphenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C17H22N2O2, CAS 1883429-25-1
5-[4-[(Dimethylamino)methyl]-3-methoxyphenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 1883429-25-1C17H22N2O2
2(1H)-Pyridinone, 5-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-1,3,4-trimethyl- chemical structure, C19H26N2O3, CAS 1883429-33-1
2(1H)-Pyridinone, 5-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-1,3,4-trimethyl-
CAS 1883429-33-1C19H26N2O3
6-Amino-5-phenylpyridin-2-ol chemical structure, C11H10N2O, CAS 856965-78-1
6-Amino-5-phenylpyridin-2-ol
CAS 856965-78-1C11H10N2O
5-(4-Fluorophenyl)-4-(hydroxymethyl)-1H-pyridin-2-one chemical structure, C12H10FNO2, CAS 1227571-41-6
5-(4-Fluorophenyl)-4-(hydroxymethyl)-1H-pyridin-2-one
CAS 1227571-41-6C12H10FNO2
1,2-Dihydro-2-oxo-5-phenyl-3-pyridineacetonitrile chemical structure, C13H10N2O, CAS 1227576-61-5
1,2-Dihydro-2-oxo-5-phenyl-3-pyridineacetonitrile
CAS 1227576-61-5C13H10N2O
5-(3-Chlorophenyl)-6-methylpyridin-2(1H)-one chemical structure, C12H10ClNO, CAS 1258625-24-9
5-(3-Chlorophenyl)-6-methylpyridin-2(1H)-one
CAS 1258625-24-9C12H10ClNO
5-(4-Hydroxyphenyl)-3-methylpyridin-2(1H)-one chemical structure, C12H11NO2, CAS 1258616-36-2
5-(4-Hydroxyphenyl)-3-methylpyridin-2(1H)-one
CAS 1258616-36-2C12H11NO2
5-(3-Bromophenyl)-1-methyl-2(1H)-pyridinone chemical structure, C12H10BrNO, CAS 1911568-63-2
5-(3-Bromophenyl)-1-methyl-2(1H)-pyridinone
CAS 1911568-63-2C12H10BrNO
6-Hydroxy-3-phenylpyridine-2-carbonitrile chemical structure, C12H8N2O, CAS 2091789-87-4
6-Hydroxy-3-phenylpyridine-2-carbonitrile
CAS 2091789-87-4C12H8N2O
5-(2-Fluorophenyl)-1,2-dihydro-2-oxo-4-pyridineacetic acid chemical structure, C13H10FNO3, CAS 1227513-62-3
5-(2-Fluorophenyl)-1,2-dihydro-2-oxo-4-pyridineacetic acid
CAS 1227513-62-3C13H10FNO3
2-[3-(4-Fluorophenyl)-6-oxo-1H-pyridin-2-yl]acetonitrile chemical structure, C13H9FN2O, CAS 1227571-30-3
2-[3-(4-Fluorophenyl)-6-oxo-1H-pyridin-2-yl]acetonitrile
CAS 1227571-30-3C13H9FN2O
5-(4-Fluorophenyl)-1,2-dihydro-2-oxo-3-pyridineacetic acid chemical structure, C13H10FNO3, CAS 1227603-87-3
5-(4-Fluorophenyl)-1,2-dihydro-2-oxo-3-pyridineacetic acid
CAS 1227603-87-3C13H10FNO3
5-(3-Aminophenyl)pyridin-2-ol hydrobromide chemical structure, C11H11BrN2O, CAS 2172594-96-4
5-(3-Aminophenyl)pyridin-2-ol hydrobromide
CAS 2172594-96-4C11H11BrN2O
3-Amino-2-hydroxy-5-(perfluorophenyl)pyridine chemical structure, C11H5F5N2O, CAS 1259477-92-3
3-Amino-2-hydroxy-5-(perfluorophenyl)pyridine
CAS 1259477-92-3C11H5F5N2O
3-Amino-5-[2-(trifluoromethoxy)phenyl]-1H-pyridin-2-one chemical structure, C12H9F3N2O2, CAS 1261839-47-7
3-Amino-5-[2-(trifluoromethoxy)phenyl]-1H-pyridin-2-one
CAS 1261839-47-7C12H9F3N2O2
Methyl 2-oxo-5-(2,4,5-trichlorophenyl)-1,2-dihydropyridine-4-carboxylate chemical structure, C13H8Cl3NO3, CAS 1261567-72-9
Methyl 2-oxo-5-(2,4,5-trichlorophenyl)-1,2-dihydropyridine-4-carboxylate
CAS 1261567-72-9C13H8Cl3NO3
3-Chloro-5-(2-(trifluoromethoxy)phenyl)pyridin-2-ol chemical structure, C12H7ClF3NO2, CAS 1261867-07-5
3-Chloro-5-(2-(trifluoromethoxy)phenyl)pyridin-2-ol
CAS 1261867-07-5C12H7ClF3NO2
3-Chloro-5-(3-(trifluoromethoxy)phenyl)pyridin-2-ol chemical structure, C12H7ClF3NO2, CAS 1261614-17-8
3-Chloro-5-(3-(trifluoromethoxy)phenyl)pyridin-2-ol
CAS 1261614-17-8C12H7ClF3NO2
3-Chloro-5-(4-(trifluoromethoxy)phenyl)pyridin-2-ol chemical structure, C12H7ClF3NO2, CAS 1261484-29-0
3-Chloro-5-(4-(trifluoromethoxy)phenyl)pyridin-2-ol
CAS 1261484-29-0C12H7ClF3NO2
6-Hydroxy-2-methyl-3-(2-(trifluoromethoxy)phenyl)pyridine chemical structure, C13H10F3NO2, CAS 1258609-80-1
6-Hydroxy-2-methyl-3-(2-(trifluoromethoxy)phenyl)pyridine
CAS 1258609-80-1C13H10F3NO2
6-Hydroxy-2-methyl-3-(3-(trifluoromethoxy)phenyl)pyridine chemical structure, C13H10F3NO2, CAS 1258624-86-0
6-Hydroxy-2-methyl-3-(3-(trifluoromethoxy)phenyl)pyridine
CAS 1258624-86-0C13H10F3NO2
2-Hydroxy-4-methyl-5-(2-(trifluoromethoxy)phenyl)pyridine chemical structure, C13H10F3NO2, CAS 1258633-39-4
2-Hydroxy-4-methyl-5-(2-(trifluoromethoxy)phenyl)pyridine
CAS 1258633-39-4C13H10F3NO2
2-Hydroxy-4-methyl-5-(3-(trifluoromethoxy)phenyl)pyridine chemical structure, C13H10F3NO2, CAS 1258620-29-9
2-Hydroxy-4-methyl-5-(3-(trifluoromethoxy)phenyl)pyridine
CAS 1258620-29-9C13H10F3NO2