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Murcko scaffold

2-Hydroxy-5-phenylpyridine scaffold

776 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
776
With full pages
32
Scaffold SMILES

O=c1ccc(-c2ccccc2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-5-phenylpyridine page
Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 625 to 672 of 776 chemicals

5-[4-(Chloromethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C14H14ClNO, CAS 2001080-41-5
5-[4-(Chloromethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 2001080-41-5C14H14ClNO
5-[3,5-Dimethoxy-4-(methoxymethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C17H21NO4, CAS 2001081-61-2
5-[3,5-Dimethoxy-4-(methoxymethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 2001081-61-2C17H21NO4
5-[4-(Aminomethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C14H16N2O, CAS 2001081-80-5
5-[4-(Aminomethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 2001081-80-5C14H16N2O
5-[3-(Aminomethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C14H16N2O, CAS 2001081-89-4
5-[3-(Aminomethyl)phenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 2001081-89-4C14H16N2O
5-(4-Aminophenyl)-1,3-dimethyl-2(1H)-pyridinone chemical structure, C13H14N2O, CAS 2001081-92-9
5-(4-Aminophenyl)-1,3-dimethyl-2(1H)-pyridinone
CAS 2001081-92-9C13H14N2O
5-[4-(Aminomethyl)-3-methylphenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C15H18N2O, CAS 2001081-93-0
5-[4-(Aminomethyl)-3-methylphenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 2001081-93-0C15H18N2O
5-[4-(Aminomethyl)-3-methoxyphenyl]-1,3-dimethyl-2(1H)-pyridinone chemical structure, C15H18N2O2, CAS 2001081-97-4
5-[4-(Aminomethyl)-3-methoxyphenyl]-1,3-dimethyl-2(1H)-pyridinone
CAS 2001081-97-4C15H18N2O2
5-[3-(Difluoromethoxy)phenyl]-1,3-dimethylpyridin-2-one chemical structure, C14H13F2NO2, CAS 2001082-02-4
5-[3-(Difluoromethoxy)phenyl]-1,3-dimethylpyridin-2-one
CAS 2001082-02-4C14H13F2NO2
5-[4-(Aminomethyl)phenyl]-1,3,6-trimethyl-2(1H)-pyridinone chemical structure, C15H18N2O, CAS 2001082-37-5
5-[4-(Aminomethyl)phenyl]-1,3,6-trimethyl-2(1H)-pyridinone
CAS 2001082-37-5C15H18N2O
1,3-Dimethyl-5-[4-[(methylamino)methyl]phenyl]-2(1H)-pyridinone chemical structure, C15H18N2O, CAS 2001082-68-2
1,3-Dimethyl-5-[4-[(methylamino)methyl]phenyl]-2(1H)-pyridinone
CAS 2001082-68-2C15H18N2O
5-(3-Methoxy-4-((methylamino)methyl)phenyl)-1,3-dimethylpyridin-2(1H)-one chemical structure, C16H20N2O2, CAS 2001082-73-9
5-(3-Methoxy-4-((methylamino)methyl)phenyl)-1,3-dimethylpyridin-2(1H)-one
CAS 2001082-73-9C16H20N2O2
5-[4-(Aminomethyl)phenyl]-1,2-dihydropyridin-2-one dihydrobromide chemical structure, C12H14Br2N2O, CAS 2241142-11-8
5-[4-(Aminomethyl)phenyl]-1,2-dihydropyridin-2-one dihydrobromide
CAS 2241142-11-8C12H14Br2N2O
5-[4-(Aminomethyl)phenyl]-1,2-dihydropyridin-2-one chemical structure, C12H12N2O, CAS 1824217-67-5
5-[4-(Aminomethyl)phenyl]-1,2-dihydropyridin-2-one
CAS 1824217-67-5C12H12N2O
6-Amino-5-phenylpyridin-2-ol hydrochloride chemical structure, C11H11ClN2O, CAS 2243514-40-9
6-Amino-5-phenylpyridin-2-ol hydrochloride
CAS 2243514-40-9C11H11ClN2O
Methyl 5-(4-aminophenyl)-2-oxo-1H-pyridine-3-carboxylate chemical structure, C13H12N2O3, CAS 908581-51-1
Methyl 5-(4-aminophenyl)-2-oxo-1H-pyridine-3-carboxylate
CAS 908581-51-1C13H12N2O3
2,6-Dimethoxy-4-(1,4,5-trimethyl-6-oxo-3-pyridinyl)benzaldehyde chemical structure, C17H19NO4, CAS 2633634-64-5
2,6-Dimethoxy-4-(1,4,5-trimethyl-6-oxo-3-pyridinyl)benzaldehyde
CAS 2633634-64-5C17H19NO4
5-(4-Amino-3-fluorophenyl)pyridin-2-ol chemical structure, C11H9FN2O, CAS 2639539-39-0
5-(4-Amino-3-fluorophenyl)pyridin-2-ol
CAS 2639539-39-0C11H9FN2O
3-Amino-1-methyl-5-(3-(trifluoromethoxy)phenyl)pyridin-2(1H)-one chemical structure, C13H11F3N2O2, CAS 2989079-77-6
3-Amino-1-methyl-5-(3-(trifluoromethoxy)phenyl)pyridin-2(1H)-one
CAS 2989079-77-6C13H11F3N2O2
3-Amino-1-methyl-5-(4-(trifluoromethoxy)phenyl)pyridin-2(1H)-one chemical structure, C13H11F3N2O2, CAS 2989371-08-4
3-Amino-1-methyl-5-(4-(trifluoromethoxy)phenyl)pyridin-2(1H)-one
CAS 2989371-08-4C13H11F3N2O2
3-Cyano-5-phenyl-6-(trifluoromethyl)-2(1H)-pyridinone chemical structure, C13H7F3N2O, CAS 2301851-22-7
3-Cyano-5-phenyl-6-(trifluoromethyl)-2(1H)-pyridinone
CAS 2301851-22-7C13H7F3N2O
Ethyl 2-oxo-5-[2-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxylate chemical structure, C15H12F3NO3, CAS 1261886-65-0
Ethyl 2-oxo-5-[2-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxylate
CAS 1261886-65-0C15H12F3NO3
6-Amino-5-(3-fluorophenyl)-1,2-dihydro-4-methyl-2-oxo-3-pyridinecarbonitrile chemical structure, C13H10FN3O, CAS 31695-67-7
6-Amino-5-(3-fluorophenyl)-1,2-dihydro-4-methyl-2-oxo-3-pyridinecarbonitrile
CAS 31695-67-7C13H10FN3O
3-(4-Chlorophenyl)-6-hydroxy-2(1H)-pyridinone chemical structure, C11H8ClNO2, CAS 856954-88-6
3-(4-Chlorophenyl)-6-hydroxy-2(1H)-pyridinone
CAS 856954-88-6C11H8ClNO2
Ethyl 1,2-dihydro-6-methyl-2-oxo-5-phenyl-4-pyridinecarboxylate chemical structure, C15H15NO3, CAS 92851-15-5
Ethyl 1,2-dihydro-6-methyl-2-oxo-5-phenyl-4-pyridinecarboxylate
CAS 92851-15-5C15H15NO3