Murcko scaffold
2-Hydroxy-5-phenylpyridine scaffold
776 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 776
- With full pages
- 32
Scaffold SMILES
O=c1ccc(-c2ccccc2)c[nH]1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1](/scaffold/RWFAQYWIBBVEBY-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 97 to 144 of 776 chemicals
5-(3-Fluorophenyl)-3-methylpyridin-2-ol
CAS 1214342-49-0C12H10FNO
5-(4-Fluorophenyl)-3-methylpyridin-2-ol
CAS 1214349-00-4C12H10FNO
5-(3-Fluorophenyl)-4-methyl-1H-pyridin-2-one
CAS 1214363-56-0C12H10FNO
5-(2-Fluorophenyl)-6-(trifluoromethyl)pyridin-2-ol
CAS 1214390-84-7C12H7F4NO
5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridin-2-ol
CAS 1214329-19-7C12H7F4NO
5-(4-Fluorophenyl)-6-(trifluoromethyl)pyridin-2-ol
CAS 1214390-86-9C12H7F4NO
5-(2-Fluorophenyl)-2-hydroxyisonicotinic acid
CAS 1214359-34-8C12H8FNO3
5-(3-Fluorophenyl)-2-hydroxyisonicotinic acid
CAS 1214346-68-5C12H8FNO3
5-(4-Fluorophenyl)-2-hydroxyisonicotinic acid
CAS 1214359-30-4C12H8FNO3
5-(2-Fluorophenyl)-3-(trifluoromethyl)pyridin-2-ol
CAS 1214369-93-3C12H7F4NO
5-(3-Fluorophenyl)-3-(trifluoromethyl)pyridin-2-ol
CAS 1214328-28-5C12H7F4NO
5-(4-Fluorophenyl)-3-(trifluoromethyl)pyridin-2-ol
CAS 1214379-09-5C12H7F4NO
3-Chloro-5-phenylpyridin-2-ol
CAS 1214348-99-8C11H8ClNO
3-Methyl-5-phenylpyridin-2-ol
CAS 1214368-89-4C12H11NO
2-Hydroxy-5-phenylisonicotinic acid
CAS 1214369-68-2C12H9NO3
2-Hydroxy-5-phenyl-3-(trifluoromethyl)pyridine
CAS 1214389-52-2C12H8F3NO
6-Hydroxy-3-phenyl-2-(trifluoromethyl)pyridine
CAS 1214380-66-1C12H8F3NO
5-(3-Cyanophenyl)-2-hydroxypyridine
CAS 1198416-57-7C12H8N2O
5-(4-Cyanophenyl)-2-hydroxypyridine
CAS 1111106-18-3C12H8N2O
5-(2-Formylphenyl)-2-hydroxypyridine
CAS 1111115-70-8C12H9NO2
3-(6-Hydroxypyridin-3-yl)benzaldehyde
CAS 1111102-83-0C12H9NO2
5-(2,3-Dimethylphenyl)-2-hydroxypyridine
CAS 1111109-94-4C13H13NO
5-(2,5-Dimethylphenyl)-2-hydroxypyridine
CAS 1111102-73-8C13H13NO
5-(2,4-Dimethylphenyl)-2-hydroxypyridine
CAS 1111115-90-2C13H13NO
- 5-(3,5-Dimethylphenyl)-2-hydroxypyridine1111109-69-3C13H13NO
- 2-Hydroxy-5-(2-hydroxymethylphenyl)pyridine1111102-80-7C12H11NO2
- 5-[3-(Hydroxymethyl)phenyl]pyridin-2-ol1111102-81-8C12H11NO2
- 2-Hydroxy-5-(4-hydroxymethylphenyl)pyridine1111115-98-0C12H11NO2
- 5-(2-Fluoro-4-methylphenyl)-2-hydroxypyridine1111109-68-2C12H10FNO
- 5-(2-Fluoro-5-methylphenyl)pyridin-2(1H)-one1111109-59-1C12H10FNO
- 5-(3-Fluoro-2-methylphenyl)-2-hydroxypyridine1261995-46-3C12H10FNO
- 5-(3-Fluoro-4-methylphenyl)-2-hydroxypyridine1111109-63-7C12H10FNO
- 5-(4-Fluoro-3-methylphenyl)-2-hydroxypyridine1111109-19-3C12H10FNO
- 5-(5-Fluoro-2-methylphenyl)-2-hydroxypyridine1111109-58-0C12H10FNO
- 5-(3-Fluoro-4-hydroxyphenyl)pyridin-2(1H)-one1111109-87-5C11H8FNO2
- 5-(3-Fluoro-5-hydroxyphenyl)pyridin-2(1H)-one1261971-69-0C11H8FNO2
- 5-(4-Fluoro-2-hydroxyphenyl)-2-hydroxypyridine1261895-41-3C11H8FNO2
- 5-(5-Fluoro-2-hydroxyphenyl)pyridin-2(1H)-one1111110-27-0C11H8FNO2
- 5-(2,4-Difluorophenyl)pyridin-2(1H)-one1111109-27-3C11H7F2NO
- 5-(3,4-Difluorophenyl)pyridin-2(1H)-one1111109-62-6C11H7F2NO
- 5-(3,5-Difluorophenyl)pyridin-2(1H)-one1111109-46-6C11H7F2NO
- 5-(2,3-Difluorophenyl)pyridin-2(1H)-one1111106-10-5C11H7F2NO
- 5-(2,6-Difluorophenyl)-2-hydroxypyridine1111109-52-4C11H7F2NO
- 5-(2,5-Difluorophenyl)pyridin-2(1H)-one1111110-02-1C11H7F2NO
- 5-(3-Acetylphenyl)-2-hydroxypyridine1111110-05-4C13H11NO2
- 5-(4-Acetylphenyl)-2-hydroxypyridine1111109-35-3C13H11NO2
- 5-(5-Cyano-2-fluorophenyl)-2-hydroxypyridine1111115-79-7C12H7FN2O
- 5-(3-Cyano-2-fluorophenyl)-2-hydroxypyridine1261908-16-0C12H7FN2O
Related scaffolds
Same ring framework with different atoms or bond orders
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c1ccc(-c2ccccn2)cc1219 chemicals
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c1ccc(N2CCNCC2)nc1112 chemicals
c1ccc(-c2ncccn2)cc1107 chemicals