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Murcko scaffold

2-Hydroxy-5-phenylpyridine scaffold

776 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
776
With full pages
32
Scaffold SMILES

O=c1ccc(-c2ccccc2)c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-5-phenylpyridine page
Murcko scaffold O=c1ccc(-c2ccccc2)c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 776 chemicals

5-(2-Chlorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile chemical structure, C12H7ClN2O, CAS 76053-37-7
5-(2-Chlorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile
CAS 76053-37-7C12H7ClN2O
1-Methyl-5-phenylpyridin-2(1H)-one chemical structure, C12H11NO, CAS 107971-01-7
1-Methyl-5-phenylpyridin-2(1H)-one
CAS 107971-01-7C12H11NO
4-(5-Cyano-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)benzoic acid chemical structure, C14H10N2O3, CAS 88594-83-6
4-(5-Cyano-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)benzoic acid
CAS 88594-83-6C14H10N2O3
3-Bromo-4-methoxy-5-(4-methoxyphenyl)-1-methylpyridin-2(1H)-one chemical structure, C14H14BrNO3, CAS 920490-79-5
3-Bromo-4-methoxy-5-(4-methoxyphenyl)-1-methylpyridin-2(1H)-one
CAS 920490-79-5C14H14BrNO3
2-Hydroxy-5-(4-trifluoromethylphenyl)pyridine chemical structure, C12H8F3NO, CAS 577967-77-2
2-Hydroxy-5-(4-trifluoromethylphenyl)pyridine
CAS 577967-77-2C12H8F3NO
2-Hydroxy-5-(4-trifluoromethylphenyl)nicotinic acid chemical structure, C13H8F3NO3, CAS 577967-76-1
2-Hydroxy-5-(4-trifluoromethylphenyl)nicotinic acid
CAS 577967-76-1C13H8F3NO3
5-(4-Ethoxycarbonylphenyl)-2-hydroxypyridine chemical structure, C14H13NO3, CAS 281233-45-2
5-(4-Ethoxycarbonylphenyl)-2-hydroxypyridine
CAS 281233-45-2C14H13NO3
2(1H)-Pyridinone, 5-(3,4-dihydroxyphenyl)-(9CI) chemical structure, C11H9NO3, CAS 146535-46-8
2(1H)-Pyridinone, 5-(3,4-dihydroxyphenyl)-(9CI)
CAS 146535-46-8C11H9NO3
5-(4-Methoxyphenyl)pyridin-2(1H)-one chemical structure, C12H11NO2, CAS 53242-51-6
5-(4-Methoxyphenyl)pyridin-2(1H)-one
CAS 53242-51-6C12H11NO2
5-(2,4-Dichlorophenyl)-2-hydroxynicotinic acid chemical structure, C12H7Cl2NO3, CAS 103824-12-0
5-(2,4-Dichlorophenyl)-2-hydroxynicotinic acid
CAS 103824-12-0C12H7Cl2NO3
5-(2,4-Dichlorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile chemical structure, C12H6Cl2N2O, CAS 103824-11-9
5-(2,4-Dichlorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile
CAS 103824-11-9C12H6Cl2N2O
5-(2-Chlorophenyl)pyridin-2(1H)-one chemical structure, C11H8ClNO, CAS 76053-47-9
5-(2-Chlorophenyl)pyridin-2(1H)-one
CAS 76053-47-9C11H8ClNO
5-(2,4-Dichlorophenyl)pyridin-2(1H)-one chemical structure, C11H7Cl2NO, CAS 103824-13-1
5-(2,4-Dichlorophenyl)pyridin-2(1H)-one
CAS 103824-13-1C11H7Cl2NO
2-Hydroxy-5-(3-methoxyphenyl)nicotinic acid chemical structure, C13H11NO4, CAS 76876-88-5
2-Hydroxy-5-(3-methoxyphenyl)nicotinic acid
CAS 76876-88-5C13H11NO4
2-Hydroxy-5-(3-methoxyphenyl)pyridine chemical structure, C12H11NO2, CAS 76876-87-4
2-Hydroxy-5-(3-methoxyphenyl)pyridine
CAS 76876-87-4C12H11NO2
2-Hydroxy-5-(2-methylphenyl)pyridine chemical structure, C12H11NO, CAS 41216-08-4
2-Hydroxy-5-(2-methylphenyl)pyridine
CAS 41216-08-4C12H11NO
5-(2-Fluorophenyl)pyridin-2(1H)-one chemical structure, C11H8FNO, CAS 1111105-99-7
5-(2-Fluorophenyl)pyridin-2(1H)-one
CAS 1111105-99-7C11H8FNO
2-Hydroxy-5-(3-methylphenyl)pyridine chemical structure, C12H11NO, CAS 1111109-83-1
2-Hydroxy-5-(3-methylphenyl)pyridine
CAS 1111109-83-1C12H11NO
2-Hydroxy-5-(2-methylphenyl)nicotinic acid chemical structure, C13H11NO3, CAS 1261966-59-9
2-Hydroxy-5-(2-methylphenyl)nicotinic acid
CAS 1261966-59-9C13H11NO3
2-Hydroxy-5-(3-nitrophenyl)pyridine chemical structure, C11H8N2O3, CAS 1111106-29-6
2-Hydroxy-5-(3-nitrophenyl)pyridine
CAS 1111106-29-6C11H8N2O3
2-Hydroxy-5-(2-trifluoromethylphenyl)pyridine chemical structure, C12H8F3NO, CAS 1111109-25-1
2-Hydroxy-5-(2-trifluoromethylphenyl)pyridine
CAS 1111109-25-1C12H8F3NO
5-(2-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C12H7FN2O, CAS 1203561-45-8
5-(2-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 1203561-45-8C12H7FN2O
2-Hydroxy-5-(4-methoxyphenyl)nicotinic acid chemical structure, C13H11NO4, CAS 1261989-06-3
2-Hydroxy-5-(4-methoxyphenyl)nicotinic acid
CAS 1261989-06-3C13H11NO4
2-Hydroxy-5-(4-methylphenyl)pyridine chemical structure, C12H11NO, CAS 1111115-93-5
2-Hydroxy-5-(4-methylphenyl)pyridine
CAS 1111115-93-5C12H11NO