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Murcko scaffold

Ring system with 2 rings and 21 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
12
With full pages
6
Scaffold SMILES

O=C(CNS(=O)(=O)c1ccccc1)NCc1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNS(=O)(=O)c1ccccc1)NCc1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-[Methyl-(4-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C16H19N3O3S, CAS 501914-64-3
2-[Methyl-(4-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 501914-64-3C16H19N3O3S
2-[(4-Fluorophenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C15H16FN3O3S, CAS 675861-38-8
2-[(4-Fluorophenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 675861-38-8C15H16FN3O3S
2-[(4-Chlorophenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C15H16ClN3O3S, CAS 499113-83-6
2-[(4-Chlorophenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 499113-83-6C15H16ClN3O3S
2-[Benzenesulfonyl(methyl)amino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C15H17N3O3S, CAS 593262-17-0
2-[Benzenesulfonyl(methyl)amino]-N-(pyridin-3-ylmethyl)acetamide
CAS 593262-17-0C15H17N3O3S
2-[(3-Chloro-4-methoxyphenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C16H18ClN3O4S, CAS 718602-74-5
2-[(3-Chloro-4-methoxyphenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 718602-74-5C16H18ClN3O4S
2-[(4-Bromophenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C15H16BrN3O3S, CAS 499113-70-1
2-[(4-Bromophenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 499113-70-1C15H16BrN3O3S
2-[Ethyl-(4-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C17H21N3O3S, CAS 831244-71-4
2-[Ethyl-(4-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 831244-71-4C17H21N3O3S
2-[(4-Methoxy-3-methylphenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C17H21N3O4S, CAS 835890-64-7
2-[(4-Methoxy-3-methylphenyl)sulfonyl-methylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 835890-64-7C17H21N3O4S
2-[Ethyl-(4-methoxyphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C17H21N3O4S, CAS 838904-97-5
2-[Ethyl-(4-methoxyphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 838904-97-5C17H21N3O4S
2-[Ethyl-(4-fluorophenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide chemical structure, C16H18FN3O3S, CAS 838905-25-2
2-[Ethyl-(4-fluorophenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
CAS 838905-25-2C16H18FN3O3S
2-(4-Methylbenzenesulfonamido)-N-[(pyridin-3-yl)methyl]butanamide chemical structure, C17H21N3O3S, CAS 1025739-06-3
2-(4-Methylbenzenesulfonamido)-N-[(pyridin-3-yl)methyl]butanamide
CAS 1025739-06-3C17H21N3O3S
2-(N-Methyl5-fluoro-2-methoxybenzenesulfonamido)-N-[(pyridin-3-yl)methyl]acetamide chemical structure, C16H18FN3O4S, CAS 931229-92-4
2-(N-Methyl5-fluoro-2-methoxybenzenesulfonamido)-N-[(pyridin-3-yl)methyl]acetamide
CAS 931229-92-4C16H18FN3O4S