CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 15 atoms

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
16
With full pages
3
Scaffold SMILES

c1ccc(OCCSc2nncs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCCSc2nncs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

5-[(2-Phenoxyethyl)sulfanyl]-1,3,4-thiadiazol-2-amine chemical structure, C10H11N3OS2, CAS 299443-63-3
5-[(2-Phenoxyethyl)sulfanyl]-1,3,4-thiadiazol-2-amine
CAS 299443-63-3C10H11N3OS2
N-[5-(2-Phenoxyethylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C12H13N3O2S2, CAS 364340-01-2
N-[5-(2-Phenoxyethylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 364340-01-2C12H13N3O2S2
5-((2-(4-Bromophenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine chemical structure, C10H10BrN3OS2, CAS 733760-42-4
5-((2-(4-Bromophenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine
CAS 733760-42-4C10H10BrN3OS2
5-[2-(3-Bromophenoxy)ethylsulfanyl]-1,3,4-thiadiazol-2-amine chemical structure, C10H10BrN3OS2, CAS 735323-91-8
5-[2-(3-Bromophenoxy)ethylsulfanyl]-1,3,4-thiadiazol-2-amine
CAS 735323-91-8C10H10BrN3OS2
S-{5-[(2-Phenoxyethyl)sulfanyl]-1,3,4-thiadiazol-2-yl} N,N-dimethylcarbamothioate chemical structure, C13H15N3O2S3, CAS 477856-14-7
S-{5-[(2-Phenoxyethyl)sulfanyl]-1,3,4-thiadiazol-2-yl} N,N-dimethylcarbamothioate
CAS 477856-14-7C13H15N3O2S3
5-{[2-(4-Methylphenoxy)ethyl]thio}-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3OS2, CAS 420825-84-9
5-{[2-(4-Methylphenoxy)ethyl]thio}-1,3,4-thiadiazol-2-amine
CAS 420825-84-9C11H13N3OS2
2-Methyl-5-[(2-phenoxyethyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C11H12N2OS2, CAS 339011-37-9
2-Methyl-5-[(2-phenoxyethyl)sulfanyl]-1,3,4-thiadiazole
CAS 339011-37-9C11H12N2OS2
5-{[2-(2-Chlorophenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine chemical structure, C10H10ClN3OS2, CAS 404376-76-7
5-{[2-(2-Chlorophenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine
CAS 404376-76-7C10H10ClN3OS2
5-{[2-(3-Methylphenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3OS2, CAS 565426-83-7
5-{[2-(3-Methylphenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine
CAS 565426-83-7C11H13N3OS2
4-(2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)ethoxy)benzonitrile chemical structure, C11H10N4OS2, CAS 930073-11-3
4-(2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)ethoxy)benzonitrile
CAS 930073-11-3C11H10N4OS2
5-((2-(2,5-Dimethylphenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine chemical structure, C12H15N3OS2, CAS 923156-04-1
5-((2-(2,5-Dimethylphenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine
CAS 923156-04-1C12H15N3OS2
5-{[2-(2,6-Dimethylphenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine chemical structure, C12H15N3OS2, CAS 404372-90-3
5-{[2-(2,6-Dimethylphenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine
CAS 404372-90-3C12H15N3OS2
5-((2-(2-Fluorophenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine chemical structure, C10H10FN3OS2, CAS 1094562-99-8
5-((2-(2-Fluorophenoxy)ethyl)thio)-1,3,4-thiadiazol-2-amine
CAS 1094562-99-8C10H10FN3OS2
2-((2-(4-Bromophenoxy)ethyl)thio)-1,3,4-thiadiazole chemical structure, C10H9BrN2OS2, CAS 1247672-21-4
2-((2-(4-Bromophenoxy)ethyl)thio)-1,3,4-thiadiazole
CAS 1247672-21-4C10H9BrN2OS2
5-({2-[5-Methyl-2-(propan-2-yl)phenoxy]ethyl}sulfanyl)-1,3,4-thiadiazol-2-amine chemical structure, C14H19N3OS2, CAS 2735545-32-9
5-({2-[5-Methyl-2-(propan-2-yl)phenoxy]ethyl}sulfanyl)-1,3,4-thiadiazol-2-amine
CAS 2735545-32-9C14H19N3OS2
5-{[2-(3-Methoxyphenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3O2S2, CAS 404375-79-7
5-{[2-(3-Methoxyphenoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine
CAS 404375-79-7C11H13N3O2S2