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Murcko scaffold

Ring system with 2 rings and 15 atoms

182 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
182
With full pages
18
Scaffold SMILES

O=C(Cn1cccn1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1cccn1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 182 chemicals

N-(3,4-Dimethoxyphenyl)-2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamide chemical structure, C15H18N4O5, CAS 358731-84-7
N-(3,4-Dimethoxyphenyl)-2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamide
CAS 358731-84-7C15H18N4O5
N-(5-Chloro-2-methoxyphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide chemical structure, C14H13ClF3N3O2, CAS 355368-22-8
N-(5-Chloro-2-methoxyphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide
CAS 355368-22-8C14H13ClF3N3O2
N-(2,4-Dichlorophenyl)-2-(3,5-dimethyl-4-nitropyrazol-1-yl)acetamide chemical structure, C13H12Cl2N4O3, CAS 351520-65-5
N-(2,4-Dichlorophenyl)-2-(3,5-dimethyl-4-nitropyrazol-1-yl)acetamide
CAS 351520-65-5C13H12Cl2N4O3
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(4-cyanophenyl)acetamide chemical structure, C14H10ClF3N4O, CAS 351986-46-4
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(4-cyanophenyl)acetamide
CAS 351986-46-4C14H10ClF3N4O
2-[4-Chloro-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-N-(4-methylphenyl)acetamide chemical structure, C14H13ClF3N3O, CAS 351986-59-9
2-[4-Chloro-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-N-(4-methylphenyl)acetamide
CAS 351986-59-9C14H13ClF3N3O
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(3,4-dimethylphenyl)acetamide chemical structure, C15H15ClF3N3O, CAS 351986-63-5
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(3,4-dimethylphenyl)acetamide
CAS 351986-63-5C15H15ClF3N3O
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(2-ethylphenyl)acetamide chemical structure, C15H15ClF3N3O, CAS 351986-29-3
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(2-ethylphenyl)acetamide
CAS 351986-29-3C15H15ClF3N3O
N-(3,4-Dichlorophenyl)-2-(5-methyl-3-nitropyrazol-1-yl)acetamide chemical structure, C12H10Cl2N4O3, CAS 5622-05-9
N-(3,4-Dichlorophenyl)-2-(5-methyl-3-nitropyrazol-1-yl)acetamide
CAS 5622-05-9C12H10Cl2N4O3
2-(5-Methyl-3-nitro-1H-pyrazol-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C13H11F3N4O3, CAS 321997-17-5
2-(5-Methyl-3-nitro-1H-pyrazol-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide
CAS 321997-17-5C13H11F3N4O3
N-(5-Chloro-2-methoxyphenyl)-2-(5-methyl-3-nitro-1H-pyrazol-1-yl)acetamide chemical structure, C13H13ClN4O4, CAS 353455-23-9
N-(5-Chloro-2-methoxyphenyl)-2-(5-methyl-3-nitro-1H-pyrazol-1-yl)acetamide
CAS 353455-23-9C13H13ClN4O4
N-(3,4-Dimethoxyphenyl)-2-(5-methyl-3-nitropyrazol-1-yl)acetamide chemical structure, C14H16N4O5, CAS 352024-55-6
N-(3,4-Dimethoxyphenyl)-2-(5-methyl-3-nitropyrazol-1-yl)acetamide
CAS 352024-55-6C14H16N4O5
2-(5-Methyl-3-nitropyrazol-1-yl)-N-(2-methylsulfanylphenyl)acetamide chemical structure, C13H14N4O3S, CAS 353455-31-9
2-(5-Methyl-3-nitropyrazol-1-yl)-N-(2-methylsulfanylphenyl)acetamide
CAS 353455-31-9C13H14N4O3S
N-(2,4-Dimethoxyphenyl)-2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamide chemical structure, C15H18N4O5, CAS 345977-37-9
N-(2,4-Dimethoxyphenyl)-2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamide
CAS 345977-37-9C15H18N4O5
N-(2,5-Dimethoxyphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide chemical structure, C15H16F3N3O3, CAS 491828-48-9
N-(2,5-Dimethoxyphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide
CAS 491828-48-9C15H16F3N3O3
2-(4-Nitropyrazol-1-yl)-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C12H9F3N4O4, CAS 515122-33-5
2-(4-Nitropyrazol-1-yl)-N-[4-(trifluoromethoxy)phenyl]acetamide
CAS 515122-33-5C12H9F3N4O4
N-(2-Methylsulfanylphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide chemical structure, C14H14F3N3OS, CAS 355368-24-0
N-(2-Methylsulfanylphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide
CAS 355368-24-0C14H14F3N3OS
N-(4-Chlorophenyl)-2-(3,5-dimethyl-4-nitropyrazol-1-yl)acetamide chemical structure, C13H13ClN4O3, CAS 353463-94-2
N-(4-Chlorophenyl)-2-(3,5-dimethyl-4-nitropyrazol-1-yl)acetamide
CAS 353463-94-2C13H13ClN4O3
N-(2,4-Dimethoxyphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide chemical structure, C15H16F3N3O3, CAS 299406-04-5
N-(2,4-Dimethoxyphenyl)-2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetamide
CAS 299406-04-5C15H16F3N3O3
2-(3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C14H13F3N4O3, CAS 354989-64-3
2-(3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)-N-(2-(trifluoromethyl)phenyl)acetamide
CAS 354989-64-3C14H13F3N4O3
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-(2-ethoxyphenyl)acetamide chemical structure, C15H18N4O4, CAS 491829-78-8
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-(2-ethoxyphenyl)acetamide
CAS 491829-78-8C15H18N4O4
N-(5-Fluoro-2-methylphenyl)-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C12H11FN4O3, CAS 514855-49-3
N-(5-Fluoro-2-methylphenyl)-2-(4-nitropyrazol-1-yl)acetamide
CAS 514855-49-3C12H11FN4O3
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-(2-methoxyphenyl)acetamide chemical structure, C14H16N4O4, CAS 515177-20-5
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-(2-methoxyphenyl)acetamide
CAS 515177-20-5C14H16N4O4
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C12H8ClF3N4O3, CAS 1005597-38-5
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-(4-nitropyrazol-1-yl)acetamide
CAS 1005597-38-5C12H8ClF3N4O3
N-(3-Chloro-4-methylphenyl)-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C12H11ClN4O3, CAS 957299-05-7
N-(3-Chloro-4-methylphenyl)-2-(4-nitropyrazol-1-yl)acetamide
CAS 957299-05-7C12H11ClN4O3