Murcko scaffold
Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-3-(phenylmethylene)- scaffold
6 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 6
- With full pages
- 3
Scaffold SMILES
O=c1c2ccccc2nc2n1CCC2=Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-3-(phenylmethylene)-
CAS 18549-16-1C18H14N2O
3-(3,4-Dimethoxy-benzylidene)-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one
CAS 82083-69-0C20H18N2O3
3-[(4-Cyanophenyl)methylidene]-9-oxo-1H,2H,3H,9H-pyrrolo[2,1-b]quinazoline-6-carboxylic acid
CAS 745808-28-0C20H13N3O3
1,2,3,9-Tetrahydro-9-oxo-3-(phenylmethylene)pyrrolo[2,1-b]quinazoline-6-carboxylic acid
CAS 85743-04-0C19H14N2O3
Isaindigotone
CAS 189316-00-5C20H18N2O4
Blm-IN-1
CAS 2056014-40-3C28H35FN4O