Murcko scaffold
Ring system with 4 rings and 20 atoms
40 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 20
- Chemicals
- 40
- With full pages
- 2
Scaffold SMILES
c1ccc(Cn2ccc3nc4ccccc4nc32)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 40 of 40 chemicals
![2-Amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carbonitrile chemical structure, C18H13N5, CAS 30119-37-0](/s/YMIOGYUSBYURCL-UHFFFAOYSA-N.svg)
2-Amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carbonitrile
CAS 30119-37-0C18H13N5
![Methyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C19H16N4O2, CAS 431934-05-3](/s/FDQQTOPHHPQJQE-UHFFFAOYSA-N.svg)
Methyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 431934-05-3C19H16N4O2
![Ethyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C20H18N4O2, CAS 30119-34-7](/s/AVSYRGUXUGNSSJ-UHFFFAOYSA-N.svg)
Ethyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 30119-34-7C20H18N4O2
![Methyl 2-amino-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C20H18N4O3, CAS 488136-90-9](/s/ADODUZLVTLBDKP-UHFFFAOYSA-N.svg)
Methyl 2-amino-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 488136-90-9C20H18N4O3
Sklb-11A
CAS 433953-86-7C19H15FN4O2
![Methyl 2-amino-1-[(4-chlorophenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxylate chemical structure, C19H15ClN4O2, CAS 433947-46-7](/s/TVEICVKFFWETLM-UHFFFAOYSA-N.svg)
Methyl 2-amino-1-[(4-chlorophenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxylate
CAS 433947-46-7C19H15ClN4O2
![2-Amino-1-(4-chlorobenzyl)-N-hexyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H26ClN5O, CAS 499228-50-1](/s/LPIJSQNAPGKTDO-UHFFFAOYSA-N.svg)
2-Amino-1-(4-chlorobenzyl)-N-hexyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 499228-50-1C24H26ClN5O
![tert-Butyl 2-amino-1-[(4-methylphenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxylate chemical structure, C23H24N4O2, CAS 836646-50-5](/s/FBGIPQGINBJNME-UHFFFAOYSA-N.svg)
tert-Butyl 2-amino-1-[(4-methylphenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxylate
CAS 836646-50-5C23H24N4O2
![tert-Butyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C22H22N4O2, CAS 839703-08-1](/s/QEDUKIWTQVWGBJ-UHFFFAOYSA-N.svg)
tert-Butyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 839703-08-1C22H22N4O2
![2-Amino-N-isobutyl-1-(4-methylbenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H25N5O, CAS 840455-09-6](/s/WPVFHJLXDFMPPF-UHFFFAOYSA-N.svg)
2-Amino-N-isobutyl-1-(4-methylbenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 840455-09-6C23H25N5O
![2-Amino-1-(4-fluorobenzyl)-N-(prop-2-en-1-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C21H18FN5O, CAS 489464-66-6](/s/HCCAONYGWNRXAF-UHFFFAOYSA-N.svg)
2-Amino-1-(4-fluorobenzyl)-N-(prop-2-en-1-yl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 489464-66-6C21H18FN5O
![2-Amino-1-(4-methoxybenzyl)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H23N5O3, CAS 381173-62-2](/s/VTGDTMKEXRLPDB-UHFFFAOYSA-N.svg)
2-Amino-1-(4-methoxybenzyl)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 381173-62-2C22H23N5O3
![Isopropyl 2-amino-1-(4-chlorobenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C21H19ClN4O2, CAS 497249-08-8](/s/VITQTQNWZYMBQK-UHFFFAOYSA-N.svg)
Isopropyl 2-amino-1-(4-chlorobenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 497249-08-8C21H19ClN4O2
![2-Amino-1-benzyl-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C21H21N5O2, CAS 381202-21-7](/s/QPDYPMDASNKTRZ-UHFFFAOYSA-N.svg)
2-Amino-1-benzyl-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 381202-21-7C21H21N5O2
![Butyl 2-amino-1-(4-fluorobenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C22H21FN4O2, CAS 433693-86-8](/s/ZGOKDRGFOCLNSS-UHFFFAOYSA-N.svg)
Butyl 2-amino-1-(4-fluorobenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 433693-86-8C22H21FN4O2
![2-Amino-1-(2-chlorobenzyl)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C22H22ClN5O2, CAS 383372-53-0](/s/GHALIKTVSBIXKN-UHFFFAOYSA-N.svg)
2-Amino-1-(2-chlorobenzyl)-N-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 383372-53-0C22H22ClN5O2
![2-Amino-1-(4-chlorobenzyl)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C21H20ClN5O2, CAS 370850-36-5](/s/DWAHBFVMIQAZOM-UHFFFAOYSA-N.svg)
2-Amino-1-(4-chlorobenzyl)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 370850-36-5C21H20ClN5O2
![2-Amino-1-benzyl-N-(3-ethoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H25N5O2, CAS 371217-42-4](/s/SPQNHYJLUSTWIK-UHFFFAOYSA-N.svg)
2-Amino-1-benzyl-N-(3-ethoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 371217-42-4C23H25N5O2
![Butyl 2-amino-1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate chemical structure, C23H24N4O3, CAS 488723-31-5](/s/CZVBVASWSILCRV-UHFFFAOYSA-N.svg)
Butyl 2-amino-1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate
CAS 488723-31-5C23H24N4O3
Butyl 2-amino-1-(2-methoxybenzyl)-1H-pyrrolo(2,3-B)quinoxaline-3-carboxylate
CAS 497242-58-7C23H24N4O3
![2-Amino-1-(4-fluorobenzyl)-N-pentyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C23H24FN5O, CAS 500271-63-6](/s/FYNPHMNXVLLDAS-UHFFFAOYSA-N.svg)
2-Amino-1-(4-fluorobenzyl)-N-pentyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 500271-63-6C23H24FN5O
![2-Amino-N-(3-ethoxypropyl)-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H27N5O3, CAS 578759-99-6](/s/XBKNCZYYUUWJRM-UHFFFAOYSA-N.svg)
2-Amino-N-(3-ethoxypropyl)-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 578759-99-6C24H27N5O3
![2-Amino-N-(3-ethoxypropyl)-1-(4-methylbenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H27N5O2, CAS 841206-82-4](/s/YUSLTSYEKXDETQ-UHFFFAOYSA-N.svg)
2-Amino-N-(3-ethoxypropyl)-1-(4-methylbenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 841206-82-4C24H27N5O2
![2-Amino-N-isopentyl-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide chemical structure, C24H27N5O2, CAS 841207-03-2](/s/WVPFDAZDEDCIMU-UHFFFAOYSA-N.svg)
2-Amino-N-isopentyl-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
CAS 841207-03-2C24H27N5O2
- 2-Amino-1-(4-fluorobenzyl)-N-isopentyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide579446-04-1C23H24FN5O
- 2-Amino-N-(3-isopropoxypropyl)-1-(2-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide844663-06-5C25H29N5O3
- Propyl 2-amino-1-[(2-methoxyphenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxylate848207-99-8C22H22N4O3
- 2-Amino-1-(4-fluorobenzyl)-N-(3-isopropoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide848755-47-5C24H26FN5O2
- 2-Amino-1-(2-methoxybenzyl)-N-propyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide843634-97-9C22H23N5O2
- Butyl 2-amino-1-benzyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate433687-46-8C22H22N4O2
- Ethyl 2-amino-1-(2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate325815-66-5C21H17F3N4O2
- Methyl 2-amino-1-(1-phenylethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylate433967-14-7C20H18N4O2
- 2-Amino-1-(3,4,5-trimethoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carbonitrile844649-82-7C21H19N5O3
- 2-Methylpropyl 2-amino-1-benzylpyrrolo[3,2-b]quinoxaline-3-carboxylate836635-39-3C22H22N4O2
- 2-Amino-N-butan-2-yl-1-[(4-methylphenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxamide573708-27-7C23H25N5O
- 2-Amino-N-(sec-butyl)-1-(4-chlorobenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide840478-31-1C22H22ClN5O
- 2-Amino-1-(2-chlorobenzyl)-N-(3-isopropoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide847377-06-4C24H26ClN5O2
- 2-Amino-1-(3,4-dimethoxybenzyl)-N-isobutyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide573948-31-9C24H27N5O3
- Butan-2-yl 2-amino-1-[(4-methylphenyl)methyl]pyrrolo[3,2-b]quinoxaline-3-carboxylate848687-44-5C23H24N4O2
- 2-Amino-N-(3-ethoxypropyl)-1-(4-methoxybenzyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide577767-83-0C24H27N5O3
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