Murcko scaffold
Ring system with 4 rings and 21 atoms
44 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 44
- With full pages
- 1
Scaffold SMILES
O=c1c2ccn(Cc3ccccc3)c2nc2ccccn12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 44 of 44 chemicals
![1-Benzyl-N-(2-methoxyethyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C21H20N4O3, CAS 896818-11-4](/s/QRIZBZBUEZZSPL-UHFFFAOYSA-N.svg)
1-Benzyl-N-(2-methoxyethyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896818-11-4C21H20N4O3
![1-Benzyl-N-(3-methoxypropyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O3, CAS 896829-54-2](/s/AWKQEIYMOZSGOP-UHFFFAOYSA-N.svg)
1-Benzyl-N-(3-methoxypropyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896829-54-2C22H22N4O3
![1-Benzyl-N-butyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C23H24N4O2, CAS 896838-84-9](/s/QNAWJFYWVXVJKH-UHFFFAOYSA-N.svg)
1-Benzyl-N-butyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896838-84-9C23H24N4O2
![1-Benzyl-N-isobutyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O2, CAS 896836-92-3](/s/MSZFYZBRIFNSBT-UHFFFAOYSA-N.svg)
1-Benzyl-N-isobutyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896836-92-3C22H22N4O2
![1-Benzyl-N-isobutyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C23H24N4O2, CAS 896840-76-9](/s/TZSOVZQXPYJBJD-UHFFFAOYSA-N.svg)
1-Benzyl-N-isobutyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896840-76-9C23H24N4O2
![1-Benzyl-N-butyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O2, CAS 899401-62-8](/s/XKIOQMJVIJBDQH-UHFFFAOYSA-N.svg)
1-Benzyl-N-butyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 899401-62-8C22H22N4O2
![1-Benzyl-N,N-diethyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C23H24N4O2, CAS 899387-79-2](/s/NCDFNTFXECWHSY-UHFFFAOYSA-N.svg)
1-Benzyl-N,N-diethyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 899387-79-2C23H24N4O2
![1-Benzyl-N-isopropyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C21H20N4O2, CAS 900268-03-3](/s/OLCQQKIAIYCAEC-UHFFFAOYSA-N.svg)
1-Benzyl-N-isopropyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900268-03-3C21H20N4O2
![1-Benzyl-N-(2-methoxyethyl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O3, CAS 900288-47-3](/s/IPQYBHYKTHLQIC-UHFFFAOYSA-N.svg)
1-Benzyl-N-(2-methoxyethyl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900288-47-3C22H22N4O3
![1-Benzyl-N-isopropyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O2, CAS 896596-36-4](/s/KLEZOSQFHCUUQK-UHFFFAOYSA-N.svg)
1-Benzyl-N-isopropyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896596-36-4C22H22N4O2
![N-Allyl-1-benzyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H20N4O2, CAS 896076-42-9](/s/VYMPNDPAMWBLPZ-UHFFFAOYSA-N.svg)
N-Allyl-1-benzyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 896076-42-9C22H20N4O2
![1-Benzyl-N-(3-methoxypropyl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C23H24N4O3, CAS 900293-72-3](/s/BWPLDGVNWAXRCB-UHFFFAOYSA-N.svg)
1-Benzyl-N-(3-methoxypropyl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900293-72-3C23H24N4O3
![1-Benzyl-N-(3-hydroxypropyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C21H20N4O3, CAS 900275-38-9](/s/ORSVQXIQHSASGZ-UHFFFAOYSA-N.svg)
1-Benzyl-N-(3-hydroxypropyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900275-38-9C21H20N4O3
![1-Benzyl-N,N-diethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O2, CAS 900281-67-6](/s/BGLWQTGGUNYXPP-UHFFFAOYSA-N.svg)
1-Benzyl-N,N-diethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900281-67-6C22H22N4O2
![1-Benzyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C18H14N4O2, CAS 900282-06-6](/s/AVZXOBFBHQKZAV-UHFFFAOYSA-N.svg)
1-Benzyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900282-06-6C18H14N4O2
![1-Benzyl-N-isopropyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O2, CAS 900264-26-8](/s/VYTBWVIAJXVXTR-UHFFFAOYSA-N.svg)
1-Benzyl-N-isopropyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900264-26-8C22H22N4O2
![1-Benzyl-N,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C20H18N4O2, CAS 900264-91-7](/s/HTFUFXQHZUOEFT-UHFFFAOYSA-N.svg)
1-Benzyl-N,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900264-91-7C20H18N4O2
![1-Benzyl-N,N-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C20H18N4O2, CAS 900265-96-5](/s/ABJRQWLLCPZSIF-UHFFFAOYSA-N.svg)
1-Benzyl-N,N-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900265-96-5C20H18N4O2
![1-Benzyl-N-isobutyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C23H24N4O2, CAS 900278-36-6](/s/ZZZLXDNKTFEWAF-UHFFFAOYSA-N.svg)
1-Benzyl-N-isobutyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900278-36-6C23H24N4O2
![1-Benzyl-N-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C19H16N4O2, CAS 900278-54-8](/s/VKOWQVARXNMQGJ-UHFFFAOYSA-N.svg)
1-Benzyl-N-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900278-54-8C19H16N4O2
![1-Benzyl-N-(1-methoxypropan-2-yl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O3, CAS 900880-87-7](/s/JSODNIWCGAKCAT-UHFFFAOYSA-N.svg)
1-Benzyl-N-(1-methoxypropan-2-yl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900880-87-7C22H22N4O3
![1-Benzyl-N-butyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C23H24N4O2, CAS 900892-46-8](/s/MXVXVAVAGCYRIM-UHFFFAOYSA-N.svg)
1-Benzyl-N-butyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900892-46-8C23H24N4O2
![1-Benzyl-N-(sec-butyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C22H22N4O2, CAS 900901-33-9](/s/WQEAUNMMVPQZLA-UHFFFAOYSA-N.svg)
1-Benzyl-N-(sec-butyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900901-33-9C22H22N4O2
![1-Benzyl-N-butyl-N,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide chemical structure, C24H26N4O2, CAS 900901-77-1](/s/WOFFEHSYGYMXMM-UHFFFAOYSA-N.svg)
1-Benzyl-N-butyl-N,9-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide
CAS 900901-77-1C24H26N4O2
- 1-Benzyl-7-methyl-4-oxo-N-propyl-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900873-93-0C22H22N4O2
- 1-Benzyl-N-(3-methoxypropyl)-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900894-38-4C23H24N4O3
- Isopropyl 2-(1-benzyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamido)acetate900883-84-3C24H24N4O4
- 1-Benzyl-N-(3-isopropoxypropyl)-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900872-96-0C25H28N4O3
- 1-Benzyl-N-(3-ethoxypropyl)-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900870-53-3C24H26N4O3
- 1-Benzyl-N,7-dimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900894-37-3C20H18N4O2
- 1-Benzyl-N,N,9-trimethyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900886-24-0C21H20N4O2
- 6-Benzyl-10-methyl-2-oxo-N-[3-(propan-2-yloxy)propyl]-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxamide901271-25-8C25H28N4O3
- 1-Benzyl-4-oxo-N-propyl-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide902024-45-7C21H20N4O2
- 1-Benzyl-N-(3-ethoxypropyl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide902010-43-9C24H26N4O3
- Ethyl 2-({6-benzyl-12-methyl-2-oxo-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaen-5-yl}formamido)acetate902044-33-1C23H22N4O4
- 1-Benzyl-N-(2-hydroxyethyl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide902045-07-2C21H20N4O3
- 1-Benzyl-N-(1-methoxypropan-2-yl)-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide902021-52-7C23H24N4O3
- 6-Benzyl-2-oxo-1,6,8-triazatricyclo[7.4.0.0,3,7]trideca-3(7),4,8,10,12-pentaene-5-carboxylic acid885461-22-3C18H13N3O3
- 1-Benzyl-N-(3-isopropoxypropyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900290-96-2C24H26N4O3
- 1-Benzyl-N-isopentyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900274-43-3C24H26N4O2
- N-Allyl-1-benzyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900285-59-8C22H20N4O2
- Methyl 2-(1-benzyl-7-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamido)acetate900286-81-9C22H20N4O4
- 1-Benzyl-N-(2-hydroxyethyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxamide900257-14-9C20H18N4O3
- Methyl 1-benzyl-9-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxylate2566174-56-7C20H17N3O3
Related scaffolds
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O=C1c2ccccc2C(=O)c2c(C(=O)N3CCCCC3)coc211 chemical![Scaffold O=c1[nH]cnc2cc3c(cc12)C(Nc1ccccc1)CC3](/scaffold/XRYXHRSMGGJRJN-UHFFFAOYSA-N/structure.svg)
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