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Murcko scaffold

Ring system with 4 rings and 22 atoms

42 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
42
With full pages
5
Scaffold SMILES

O=S(=O)(c1ccccc1)c1c[nH]c2nc3ccccc3nc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1c[nH]c2nc3ccccc3nc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

N-[3-(Benzenesulfonyl)-1-prop-2-enylpyrrolo[3,2-b]quinoxalin-2-yl]acetamide chemical structure, C21H18N4O3S, CAS 373619-93-3
N-[3-(Benzenesulfonyl)-1-prop-2-enylpyrrolo[3,2-b]quinoxalin-2-yl]acetamide
CAS 373619-93-3C21H18N4O3S
1-Allyl-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C19H16N4O2S, CAS 300375-87-5
1-Allyl-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 300375-87-5C19H16N4O2S
3-(Benzenesulfonyl)-1-[3-(dimethylamino)propyl]pyrrolo[3,2-b]quinoxalin-2-amine chemical structure, C21H23N5O2S, CAS 300375-84-2
3-(Benzenesulfonyl)-1-[3-(dimethylamino)propyl]pyrrolo[3,2-b]quinoxalin-2-amine
CAS 300375-84-2C21H23N5O2S
2-(2-Amino-3-benzenesulfonyl-pyrrolo(2,3-B)quinoxalin-1-yl)-ethanol chemical structure, C18H16N4O3S, CAS 300375-88-6
2-(2-Amino-3-benzenesulfonyl-pyrrolo(2,3-B)quinoxalin-1-yl)-ethanol
CAS 300375-88-6C18H16N4O3S
2-{2-Amino-3-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]quinoxalin-1-yl}ethanol chemical structure, C19H18N4O3S, CAS 300376-28-7
2-{2-Amino-3-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]quinoxalin-1-yl}ethanol
CAS 300376-28-7C19H18N4O3S
3-[2-Amino-3-(benzenesulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-1-yl]propan-1-ol chemical structure, C19H18N4O3S, CAS 300375-86-4
3-[2-Amino-3-(benzenesulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-1-yl]propan-1-ol
CAS 300375-86-4C19H18N4O3S
2-{2-Amino-3-[(3-chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]quinoxalin-1-yl}ethanol chemical structure, C18H15ClN4O3S, CAS 881043-91-0
2-{2-Amino-3-[(3-chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]quinoxalin-1-yl}ethanol
CAS 881043-91-0C18H15ClN4O3S
3-((4-Methoxyphenyl)sulfonyl)-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C21H22N4O4S, CAS 847376-00-5
3-((4-Methoxyphenyl)sulfonyl)-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 847376-00-5C21H22N4O4S
1-Butyl-3-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C21H22N4O2S, CAS 124982-72-5
1-Butyl-3-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 124982-72-5C21H22N4O2S
3-(Benzenesulfonyl)-1-butylpyrrolo[3,2-b]quinoxalin-2-amine chemical structure, C20H20N4O2S, CAS 300375-85-3
3-(Benzenesulfonyl)-1-butylpyrrolo[3,2-b]quinoxalin-2-amine
CAS 300375-85-3C20H20N4O2S
3-{2-Amino-3-[(4-chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]quinoxalin-1-yl}propan-1-ol chemical structure, C19H17ClN4O3S, CAS 731004-47-0
3-{2-Amino-3-[(4-chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]quinoxalin-1-yl}propan-1-ol
CAS 731004-47-0C19H17ClN4O3S
1-(3-Methoxypropyl)-3-(m-tolylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C21H22N4O3S, CAS 847046-57-5
1-(3-Methoxypropyl)-3-(m-tolylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 847046-57-5C21H22N4O3S
3-(4-Chlorobenzenesulfonyl)-1-(3-methylbutyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C21H21ClN4O2S, CAS 797765-66-3
3-(4-Chlorobenzenesulfonyl)-1-(3-methylbutyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 797765-66-3C21H21ClN4O2S
1-(3-Methoxypropyl)-3-tosyl-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C21H22N4O3S, CAS 578719-24-1
1-(3-Methoxypropyl)-3-tosyl-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 578719-24-1C21H22N4O3S
1-(3-Methoxypropyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C20H20N4O3S, CAS 841209-36-7
1-(3-Methoxypropyl)-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 841209-36-7C20H20N4O3S
1-(2-Aminoethyl)-3-((4-methoxyphenyl)sulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C19H19N5O3S, CAS 843621-71-6
1-(2-Aminoethyl)-3-((4-methoxyphenyl)sulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 843621-71-6C19H19N5O3S
3-((3,4-Dimethylphenyl)sulfonyl)-1-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C21H22N4O3S, CAS 843636-70-4
3-((3,4-Dimethylphenyl)sulfonyl)-1-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 843636-70-4C21H22N4O3S
3-(3,4-Dimethylphenyl)sulfonyl-1-(3-propan-2-yloxypropyl)pyrrolo[3,2-b]quinoxalin-2-amine chemical structure, C24H28N4O3S, CAS 844460-24-8
3-(3,4-Dimethylphenyl)sulfonyl-1-(3-propan-2-yloxypropyl)pyrrolo[3,2-b]quinoxalin-2-amine
CAS 844460-24-8C24H28N4O3S
3-(2,5-Dichlorophenyl)sulfonyl-1-(2-methoxyethyl)pyrrolo[3,2-b]quinoxalin-2-amine chemical structure, C19H16Cl2N4O3S, CAS 847185-67-5
3-(2,5-Dichlorophenyl)sulfonyl-1-(2-methoxyethyl)pyrrolo[3,2-b]quinoxalin-2-amine
CAS 847185-67-5C19H16Cl2N4O3S
1-Allyl-3-(m-tolylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C20H18N4O2S, CAS 844465-29-8
1-Allyl-3-(m-tolylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 844465-29-8C20H18N4O2S
1-Butyl-3-(4-methoxyphenyl)sulfonylpyrrolo[3,2-b]quinoxalin-2-amine chemical structure, C21H22N4O3S, CAS 846597-11-3
1-Butyl-3-(4-methoxyphenyl)sulfonylpyrrolo[3,2-b]quinoxalin-2-amine
CAS 846597-11-3C21H22N4O3S
1-(2-Methoxyethyl)-3-(m-tolylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C20H20N4O3S, CAS 842977-04-2
1-(2-Methoxyethyl)-3-(m-tolylsulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 842977-04-2C20H20N4O3S
1-Allyl-3-((4-chlorophenyl)sulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C19H15ClN4O2S, CAS 843668-90-6
1-Allyl-3-((4-chlorophenyl)sulfonyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 843668-90-6C19H15ClN4O2S
3-((3,4-Dimethylphenyl)sulfonyl)-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine chemical structure, C22H24N4O3S, CAS 844837-28-1
3-((3,4-Dimethylphenyl)sulfonyl)-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxalin-2-amine
CAS 844837-28-1C22H24N4O3S