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Murcko scaffold

Ring system with 3 rings and 17 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
19
With full pages
4
Scaffold SMILES

O=C1CC2CCC1(C(=O)Nc1ccccc1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC2CCC1(C(=O)Nc1ccccc1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

Methyl 2-{[(3,3-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)carbonyl]amino}benzoate chemical structure, C18H21NO4, CAS 609334-80-7
Methyl 2-{[(3,3-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)carbonyl]amino}benzoate
CAS 609334-80-7C18H21NO4
N-(2,4-Dimethylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C18H23NO2, CAS 622360-68-3
N-(2,4-Dimethylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622360-68-3C18H23NO2
N-(4-Methoxyphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C17H21NO3, CAS 622361-90-4
N-(4-Methoxyphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-90-4C17H21NO3
N-(2,5-Dichlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H17Cl2NO2, CAS 622361-30-2
N-(2,5-Dichlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-30-2C16H17Cl2NO2
N-(4-Ethylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C18H23NO2, CAS 622359-34-6
N-(4-Ethylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622359-34-6C18H23NO2
N-(4-Chlorophenyl)-2,2-dimethyl-3-oxobicyclo[2.2.1]heptane-4-carboxamide chemical structure, C16H18ClNO2, CAS 622361-81-3
N-(4-Chlorophenyl)-2,2-dimethyl-3-oxobicyclo[2.2.1]heptane-4-carboxamide
CAS 622361-81-3C16H18ClNO2
N-(4-Acetylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C18H21NO3, CAS 622361-95-9
N-(4-Acetylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-95-9C18H21NO3
N-(3-Chlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H18ClNO2, CAS 622361-63-1
N-(3-Chlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-63-1C16H18ClNO2
N-(2,3-Dichlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H17Cl2NO2, CAS 622361-33-5
N-(2,3-Dichlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-33-5C16H17Cl2NO2
N-(4-Ethoxyphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C18H23NO3, CAS 622361-92-6
N-(4-Ethoxyphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-92-6C18H23NO3
N-(4-Bromophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H18BrNO2, CAS 609334-79-4
N-(4-Bromophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 609334-79-4C16H18BrNO2
N-(2,3-Dimethylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C18H23NO2, CAS 622360-65-0
N-(2,3-Dimethylphenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622360-65-0C18H23NO2
N-(2-Fluorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H18FNO2, CAS 622361-01-7
N-(2-Fluorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-01-7C16H18FNO2
Bicyclo[2.2.1]heptane-1-carboxamide, 3,3-dimethyl-2-oxo-n-phenyl- chemical structure, C16H19NO2, CAS 622361-48-2
Bicyclo[2.2.1]heptane-1-carboxamide, 3,3-dimethyl-2-oxo-n-phenyl-
CAS 622361-48-2C16H19NO2
7,7-Dimethyl-2-oxo-N-phenylbicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H19NO2, CAS 879562-39-7
7,7-Dimethyl-2-oxo-N-phenylbicyclo[2.2.1]heptane-1-carboxamide
CAS 879562-39-7C16H19NO2
N-(3,4-Difluorophenyl)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H17F2NO2, CAS 727686-13-7
N-(3,4-Difluorophenyl)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 727686-13-7C16H17F2NO2
N-[2-Chloro-5-(trifluoromethyl)phenyl]-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C17H17ClF3NO2, CAS 727686-12-6
N-[2-Chloro-5-(trifluoromethyl)phenyl]-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 727686-12-6C17H17ClF3NO2
N-(3,4-Difluorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H17F2NO2, CAS 728028-73-7
N-(3,4-Difluorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 728028-73-7C16H17F2NO2
N-(2-Chlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide chemical structure, C16H18ClNO2, CAS 622361-54-0
N-(2-Chlorophenyl)-3,3-dimethyl-2-oxobicyclo[2.2.1]heptane-1-carboxamide
CAS 622361-54-0C16H18ClNO2