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Murcko scaffold

Ring system with 3 rings and 18 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
4
With full pages
2
Scaffold SMILES

O=C1CC2CCC1(CS(=O)(=O)N1CCCCC1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC2CCC1(CS(=O)(=O)N1CCCCC1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

1-{[(3,5-Dimethylpiperidin-1-yl)sulfonyl]methyl}-7,7-dimethylbicyclo[2.2.1]heptan-2-one chemical structure, C17H29NO3S, CAS 1005127-35-4
1-{[(3,5-Dimethylpiperidin-1-yl)sulfonyl]methyl}-7,7-dimethylbicyclo[2.2.1]heptan-2-one
CAS 1005127-35-4C17H29NO3S
1-({7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonyl)piperidine-4-carboxamide chemical structure, C16H26N2O4S, CAS 728017-23-0
1-({7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonyl)piperidine-4-carboxamide
CAS 728017-23-0C16H26N2O4S
Bicyclo[2.2.1]heptan-2-one, 7,7-dimethyl-1-[(1-piperidinylsulfonyl)methyl]- chemical structure, C15H25NO3S, CAS 443669-48-5
Bicyclo[2.2.1]heptan-2-one, 7,7-dimethyl-1-[(1-piperidinylsulfonyl)methyl]-
CAS 443669-48-5C15H25NO3S
tert-Butyl ((S)-1-((((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methyl)sulfonyl)piperidin-3-yl)carbamate chemical structure, C20H34N2O5S, CAS 2227576-82-9
tert-Butyl ((S)-1-((((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methyl)sulfonyl)piperidin-3-yl)carbamate
CAS 2227576-82-9C20H34N2O5S