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Murcko scaffold

5,6,7,8-Tetrahydro-1,7-naphthyridine scaffold

162 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
162
With full pages
14
Scaffold SMILES

c1cnc2c(c1)CCNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydro-1,7-naphthyridine page
Murcko scaffold c1cnc2c(c1)CCNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 162 chemicals

5,6,7,8-Tetrahydro-1,7-naphthyridine chemical structure, C8H10N2, CAS 13623-85-3
5,6,7,8-Tetrahydro-1,7-naphthyridine
CAS 13623-85-3C8H10N2
5,6,7,8-Tetrahydro-1,7-naphthyridin-5-ol chemical structure, C8H10N2O, CAS 478628-40-9
5,6,7,8-Tetrahydro-1,7-naphthyridin-5-ol
CAS 478628-40-9C8H10N2O
7-Boc-3-nitro-5,6,7,8-tetrahydro-1,7-naphthyridine chemical structure, C13H17N3O4, CAS 1043689-15-1
7-Boc-3-nitro-5,6,7,8-tetrahydro-1,7-naphthyridine
CAS 1043689-15-1C13H17N3O4
2-(3-(Methoxycarbonyl)-5,6-dihydro-1,7-naphthyridin-7(8H)-YL)acetic acid chemical structure, C12H14N2O4, CAS 1092352-60-7
2-(3-(Methoxycarbonyl)-5,6-dihydro-1,7-naphthyridin-7(8H)-YL)acetic acid
CAS 1092352-60-7C12H14N2O4
Ethyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride chemical structure, C11H15ClN2O2, CAS 1207175-08-3
Ethyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride
CAS 1207175-08-3C11H15ClN2O2
Ethyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate chemical structure, C11H14N2O2, CAS 1207253-96-0
Ethyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate
CAS 1207253-96-0C11H14N2O2
7-tert-Butyl 3-methyl 5,6-dihydro-1,7-naphthyridine-3,7(8H)-dicarboxylate chemical structure, C15H20N2O4, CAS 1201784-86-2
7-tert-Butyl 3-methyl 5,6-dihydro-1,7-naphthyridine-3,7(8H)-dicarboxylate
CAS 1201784-86-2C15H20N2O4
2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine chemical structure, C9H9F3N2, CAS 741737-13-3
2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine
CAS 741737-13-3C9H9F3N2
Ethyl 2-(trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate chemical structure, C12H13F3N2O2, CAS 794461-86-2
Ethyl 2-(trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate
CAS 794461-86-2C12H13F3N2O2
tert-Butyl 4-bromo-3-cyano-5,6-dihydro-1,7-naphthyridine-7(8H)-carboxylate chemical structure, C14H16BrN3O2, CAS 1333996-55-6
tert-Butyl 4-bromo-3-cyano-5,6-dihydro-1,7-naphthyridine-7(8H)-carboxylate
CAS 1333996-55-6C14H16BrN3O2
tert-Butyl 3-cyano-4-methyl-5,6-dihydro-1,7-naphthyridine-7(8H)-carboxylate chemical structure, C15H19N3O2, CAS 1333996-57-8
tert-Butyl 3-cyano-4-methyl-5,6-dihydro-1,7-naphthyridine-7(8H)-carboxylate
CAS 1333996-57-8C15H19N3O2
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride chemical structure, C10H13ClN2O2, CAS 1253792-57-2
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate hydrochloride
CAS 1253792-57-2C10H13ClN2O2
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate chemical structure, C10H12N2O2, CAS 1253888-80-0
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate
CAS 1253888-80-0C10H12N2O2
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-6-carboxylate--hydrogen chloride (1/1) chemical structure, C10H13ClN2O2, CAS 920305-91-5
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-6-carboxylate--hydrogen chloride (1/1)
CAS 920305-91-5C10H13ClN2O2
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-6-carboxylate chemical structure, C10H12N2O2, CAS 920337-71-9
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-6-carboxylate
CAS 920337-71-9C10H12N2O2
1-(5,8-Dihydro-1,7-naphthyridin-7(6H)-yl)ethan-1-one chemical structure, C10H12N2O, CAS 1380586-66-2
1-(5,8-Dihydro-1,7-naphthyridin-7(6H)-yl)ethan-1-one
CAS 1380586-66-2C10H12N2O
1,7-Naphthyridine-6-carboxylic acid, 5,6,7,8-tetrahydro- chemical structure, C9H10N2O2, CAS 1964490-63-8
1,7-Naphthyridine-6-carboxylic acid, 5,6,7,8-tetrahydro-
CAS 1964490-63-8C9H10N2O2
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-2-carboxylate chemical structure, C10H12N2O2, CAS 1361381-37-4
Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-2-carboxylate
CAS 1361381-37-4C10H12N2O2
8-Methyl-5,6,7,8-tetrahydro-[1,7]naphthyridine chemical structure, C9H12N2, CAS 1176415-30-7
8-Methyl-5,6,7,8-tetrahydro-[1,7]naphthyridine
CAS 1176415-30-7C9H12N2
5,6,7,8-Tetrahydro-1,7-naphthyridine-2-carboxylic acid chemical structure, C9H10N2O2, CAS 1823876-18-1
5,6,7,8-Tetrahydro-1,7-naphthyridine-2-carboxylic acid
CAS 1823876-18-1C9H10N2O2
2-Methyl-5,6,7,8-tetrahydro-1,7-naphthyridine chemical structure, C9H12N2, CAS 1196146-61-8
2-Methyl-5,6,7,8-tetrahydro-1,7-naphthyridine
CAS 1196146-61-8C9H12N2
tert-Butyl 2-(hydroxymethyl)-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate chemical structure, C14H20N2O3, CAS 2605230-16-6
tert-Butyl 2-(hydroxymethyl)-5,8-dihydro-1,7-naphthyridine-7(6H)-carboxylate
CAS 2605230-16-6C14H20N2O3
7-Methyl-3-nitro-5,6,7,8-tetrahydro-1,7-naphthyridine chemical structure, C9H11N3O2, CAS 957469-41-9
7-Methyl-3-nitro-5,6,7,8-tetrahydro-1,7-naphthyridine
CAS 957469-41-9C9H11N3O2
7-Methyl-5,6,7,8-tetrahydro-1,7-naphthyridin-3-amine chemical structure, C9H13N3, CAS 957469-16-8
7-Methyl-5,6,7,8-tetrahydro-1,7-naphthyridin-3-amine
CAS 957469-16-8C9H13N3