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Murcko scaffold

Ring system with 3 rings and 18 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
16
With full pages
3
Scaffold SMILES

c1ccc(-c2ccnc(N3CCCCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc(N3CCCCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-Piperidinol, 1-(5-chloro-4-(2-chlorophenyl)-2-pyrimidinyl)-, monohydrobromide chemical structure, C15H16BrCl2N3O, CAS 93182-19-5
4-Piperidinol, 1-(5-chloro-4-(2-chlorophenyl)-2-pyrimidinyl)-, monohydrobromide
CAS 93182-19-5C15H16BrCl2N3O
4-Piperidinol, 1-(4-(4-chlorophenyl)-2-pyrimidinyl)- chemical structure, C15H16ClN3O, CAS 93182-21-9
4-Piperidinol, 1-(4-(4-chlorophenyl)-2-pyrimidinyl)-
CAS 93182-21-9C15H16ClN3O
4-Piperidinol, 1-(5-chloro-4-(4-chlorophenyl)-2-pyrimidinyl)- chemical structure, C15H15Cl2N3O, CAS 93182-22-0
4-Piperidinol, 1-(5-chloro-4-(4-chlorophenyl)-2-pyrimidinyl)-
CAS 93182-22-0C15H15Cl2N3O
4-(3,4-Dimethoxyphenyl)-2-(1-piperidinyl)-6-(trifluoromethyl)pyrimidine chemical structure, C18H20F3N3O2, CAS 725695-51-2
4-(3,4-Dimethoxyphenyl)-2-(1-piperidinyl)-6-(trifluoromethyl)pyrimidine
CAS 725695-51-2C18H20F3N3O2
1-[4-(Difluoromethyl)-6-(3,4-dimethoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid chemical structure, C19H21F2N3O4, CAS 870260-43-8
1-[4-(Difluoromethyl)-6-(3,4-dimethoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid
CAS 870260-43-8C19H21F2N3O4
1-[4-(Difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid chemical structure, C18H19F2N3O3, CAS 863209-30-7
1-[4-(Difluoromethyl)-6-(3-methoxyphenyl)pyrimidin-2-yl]piperidine-4-carboxylic acid
CAS 863209-30-7C18H19F2N3O3
1-[4-(3-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid chemical structure, C18H18F3N3O3, CAS 870980-07-7
1-[4-(3-Methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid
CAS 870980-07-7C18H18F3N3O3
4-Phenyl-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid chemical structure, C16H17N3O2, CAS 919199-71-6
4-Phenyl-2-(piperidin-1-yl)pyrimidine-5-carboxylic acid
CAS 919199-71-6C16H17N3O2
6-Phenyl-2-(piperidin-1-yl)pyrimidine-4-carboxylic acid chemical structure, C16H17N3O2, CAS 1017484-32-0
6-Phenyl-2-(piperidin-1-yl)pyrimidine-4-carboxylic acid
CAS 1017484-32-0C16H17N3O2
1-[4-(4-Ethylphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-amine chemical structure, C18H21F3N4, CAS 1018143-39-9
1-[4-(4-Ethylphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-amine
CAS 1018143-39-9C18H21F3N4
1-(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-amine chemical structure, C16H17F3N4, CAS 1018125-23-9
1-(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-amine
CAS 1018125-23-9C16H17F3N4
1-(4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-amine chemical structure, C16H16F4N4, CAS 1018143-48-0
1-(4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-amine
CAS 1018143-48-0C16H16F4N4
Ethyl 1-(4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-3-carboxylate chemical structure, C20H22F3N3O3, CAS 1018051-75-6
Ethyl 1-(4-(3-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidine-3-carboxylate
CAS 1018051-75-6C20H22F3N3O3
1-(4-(3-(tert-Butyl)-4-isopropoxyphenyl)pyrimidin-2-yl)piperidin-4-ol chemical structure, C22H31N3O2, CAS 1378367-88-4
1-(4-(3-(tert-Butyl)-4-isopropoxyphenyl)pyrimidin-2-yl)piperidin-4-ol
CAS 1378367-88-4C22H31N3O2
(1-(4-(3-(tert-Butyl)-4-isopropoxyphenyl)pyrimidin-2-yl)piperidin-4-yl)methanamine chemical structure, C23H34N4O, CAS 1378365-11-7
(1-(4-(3-(tert-Butyl)-4-isopropoxyphenyl)pyrimidin-2-yl)piperidin-4-yl)methanamine
CAS 1378365-11-7C23H34N4O
1-(4-(3-(tert-Butyl)-4-isopropoxyphenyl)pyrimidin-2-yl)piperidin-4-amine chemical structure, C22H32N4O, CAS 1378366-19-8
1-(4-(3-(tert-Butyl)-4-isopropoxyphenyl)pyrimidin-2-yl)piperidin-4-amine
CAS 1378366-19-8C22H32N4O