Murcko scaffold
2-(Cyclohexyloxy)pyridine scaffold
150 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 150
- With full pages
- 8
Scaffold SMILES
c1ccc(OC2CCCCC2)nc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 97 to 144 of 150 chemicals
4-Bromo-3-chloro-2-(cyclohexyloxy)pyridine
CAS 1881293-84-0C11H13BrClNO
![5-Chloro-6-{[4-(dimethylamino)cyclohexyl]oxy}pyridine-3-carbonitrile chemical structure, C14H18ClN3O, CAS 2199971-84-9](/s/FLPJRHFZGVMCMI-UHFFFAOYSA-N.svg)
5-Chloro-6-{[4-(dimethylamino)cyclohexyl]oxy}pyridine-3-carbonitrile
CAS 2199971-84-9C14H18ClN3O
![5-Chloro-6-[(4,4-difluorocyclohexyl)oxy]pyridine-3-carbonitrile chemical structure, C12H11ClF2N2O, CAS 2199274-23-0](/s/FWCQAOXFXMZQFL-UHFFFAOYSA-N.svg)
5-Chloro-6-[(4,4-difluorocyclohexyl)oxy]pyridine-3-carbonitrile
CAS 2199274-23-0C12H11ClF2N2O
N,N-Dimethyl-2-(pyridin-2-yloxy)cyclohexan-1-amine
CAS 2197640-40-5C13H20N2O
![2-[(4,4-Difluorocyclohexyl)oxy]pyridine chemical structure, C11H13F2NO, CAS 2197811-85-9](/s/CVTATECZAKSTQD-UHFFFAOYSA-N.svg)
2-[(4,4-Difluorocyclohexyl)oxy]pyridine
CAS 2197811-85-9C11H13F2NO
![N,N-Dimethyl-4-[(6-methylpyridin-2-yl)oxy]cyclohexan-1-amine chemical structure, C14H22N2O, CAS 2197901-93-0](/s/LVFOLBBXGHGLGI-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-[(6-methylpyridin-2-yl)oxy]cyclohexan-1-amine
CAS 2197901-93-0C14H22N2O
![N,N-Dimethyl-4-[(4-methylpyridin-2-yl)oxy]cyclohexan-1-amine chemical structure, C14H22N2O, CAS 2199132-45-9](/s/MAMGPWYMQWFYPI-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-[(4-methylpyridin-2-yl)oxy]cyclohexan-1-amine
CAS 2199132-45-9C14H22N2O
![2-{[4-(Dimethylamino)cyclohexyl]oxy}pyridine-3-carbonitrile chemical structure, C14H19N3O, CAS 2200611-77-2](/s/ZXBWVTNBEQFVGS-UHFFFAOYSA-N.svg)
2-{[4-(Dimethylamino)cyclohexyl]oxy}pyridine-3-carbonitrile
CAS 2200611-77-2C14H19N3O
![6-{[2-(Dimethylamino)cyclohexyl]oxy}pyridine-3-carbonitrile chemical structure, C14H19N3O, CAS 2197667-96-0](/s/IVHYHZSEDWKGDM-UHFFFAOYSA-N.svg)
6-{[2-(Dimethylamino)cyclohexyl]oxy}pyridine-3-carbonitrile
CAS 2197667-96-0C14H19N3O
![6-[(4,4-Difluorocyclohexyl)oxy]pyridine-3-carbonitrile chemical structure, C12H12F2N2O, CAS 2197734-99-7](/s/MDSFRVZASXQYBJ-UHFFFAOYSA-N.svg)
6-[(4,4-Difluorocyclohexyl)oxy]pyridine-3-carbonitrile
CAS 2197734-99-7C12H12F2N2O
![4-[(3-Chloropyridin-2-yl)oxy]-N,N-dimethylcyclohexan-1-amine chemical structure, C13H19ClN2O, CAS 2199132-83-5](/s/RXIORIXBKGUHFX-UHFFFAOYSA-N.svg)
4-[(3-Chloropyridin-2-yl)oxy]-N,N-dimethylcyclohexan-1-amine
CAS 2199132-83-5C13H19ClN2O
![4-[(3-Bromopyridin-2-yl)oxy]-N,N-dimethylcyclohexan-1-amine chemical structure, C13H19BrN2O, CAS 2201828-91-1](/s/GQRARTMWVZPZTF-UHFFFAOYSA-N.svg)
4-[(3-Bromopyridin-2-yl)oxy]-N,N-dimethylcyclohexan-1-amine
CAS 2201828-91-1C13H19BrN2O
![4-[(3-Fluoropyridin-2-yl)oxy]-N,N-dimethylcyclohexan-1-amine chemical structure, C13H19FN2O, CAS 2197892-08-1](/s/IFCBGIJLZBMWRH-UHFFFAOYSA-N.svg)
4-[(3-Fluoropyridin-2-yl)oxy]-N,N-dimethylcyclohexan-1-amine
CAS 2197892-08-1C13H19FN2O
![2-[(4,4-Difluorocyclohexyl)oxy]-3-fluoropyridine chemical structure, C11H12F3NO, CAS 2199686-10-5](/s/SDOPCPZLNAZNAG-UHFFFAOYSA-N.svg)
2-[(4,4-Difluorocyclohexyl)oxy]-3-fluoropyridine
CAS 2199686-10-5C11H12F3NO
4-Amino-3,5-dibromo-2-(cyclohexyloxy)pyridine
CAS 1563531-27-0C11H14Br2N2O
4-Amino-3-bromo-6-(cyclohexyloxy)pyridine
CAS 1446408-36-1C11H15BrN2O
6-(Cyclohexyloxy)-3-methylpyridine-2-carbaldehyde
CAS 1289070-71-8C13H17NO2
3-Pyridinecarboxaldehyde, 2-chloro-6-(cyclohexyloxy)-
CAS 1289177-00-9C12H14ClNO2
5-Chloro-6-(cyclohexyloxy)-3-pyridinecarboxaldehyde
CAS 1289196-37-7C12H14ClNO2
![N-[2-(Cyclohexyloxy)pyridin-4-yl]prop-2-enamide chemical structure, C14H18N2O2, CAS 2188733-68-6](/s/QFCZDBYASLWVSN-UHFFFAOYSA-N.svg)
N-[2-(Cyclohexyloxy)pyridin-4-yl]prop-2-enamide
CAS 2188733-68-6C14H18N2O2
(6-(Cyclohexyloxy)-4-fluoropyridin-3-yl)boronic acid
CAS 2225174-87-6C11H15BFNO3
(2-(Cyclohexyloxy)-5-fluoropyridin-4-yl)boronic acid
CAS 2225175-60-8C11H15BFNO3
(2-(Cyclohexyloxy)pyridin-4-yl)boronic acid
CAS 2225177-63-7C11H16BNO3
5-Bromo-6-(cyclohexyloxy)pyridine-3-boronic acid
CAS 2225175-13-1C11H15BBrNO3
- 4-[(3-Chloropyridin-2-yl)oxy]cyclohexan-1-amine dihydrochloride, trans2059909-60-1C11H17Cl3N2O
- (1R,2R)-2-Pyridin-2-yloxycyclohexan-1-amine2276687-87-5C11H16N2O
- N-[(6-Cyclohexyloxypyridin-3-yl)methyl]prop-2-enamide2361656-21-3C15H20N2O2
- (1R,2R)-2-(3-Fluoropyridin-2-yl)oxycyclohexan-1-amine2290815-04-0C11H15FN2O
- (1R,2R)-2-[(5-Chloropyridin-2-yl)oxy]cyclohexan-1-amine2277041-22-0C11H15ClN2O
- 5-[(3-Fluoropyridin-2-yl)oxy]-3,3-dimethylcyclohexan-1-amine2380098-66-6C13H19FN2O
- (1R,2R)-2-[(6-Methylpyridin-2-yl)oxy]cyclohexan-1-amine2290901-78-7C12H18N2O
- (1R,2R)-2-[(5-Methylpyridin-2-yl)oxy]cyclohexan-1-amine2277126-46-0C12H18N2O
- N-[4-(3-Cyanopyridin-2-yl)oxycyclohexyl]prop-2-enamide2411236-21-8C15H17N3O2
- 2-Chloro-N-[4-(3-cyanopyridin-2-yl)oxycyclohexyl]acetamide2411219-28-6C14H16ClN3O2
- Rac-(1r,4r)-4-(pyridin-2-yloxy)cyclohexan-1-amine hydrochloride2913229-18-0C11H17ClN2O
- (3S)-3-Amino-3-[6-(cyclohexyloxy)pyridin-3-yl]propan-1-ol1269823-71-3C14H22N2O2
- 6-(Cyclohexyloxy)-2-ethylpyridine-3-carbaldehyde1289171-91-0C14H19NO2
- 6-{[(1R,2R)-2-Aminocyclohexyl]oxy}pyridine-2-carboxylic acid dihydrochloride2763741-02-0C12H18Cl2N2O3
- (1r,4r)-4-[(5-Bromopyridin-2-yl)oxy]cyclohexan-1-amine dihydrochloride2751603-12-8C11H17BrCl2N2O
- Ethyl 6-[(4-aminocyclohexyl)oxy]pyridine-3-carboxylate dihydrochloride2751603-31-1C14H22Cl2N2O3
- N-[(1r,4r)-4-[(3-Cyanopyridin-2-yl)oxy]cyclohexyl]but-2-ynamide2411307-55-4C16H17N3O2
- (2E)-4-(Dimethylamino)-N-[(1r,4r)-4-[(3-cyanopyridin-2-yl)oxy]cyclohexyl]but-2-enamide2728727-88-4C18H24N4O2
- 6-[(4-{[(tert-Butoxy)carbonyl]amino}cyclohexyl)oxy]pyridine-3-carboxylic acid2639450-70-5C17H24N2O5
- Methyl 6-[(4-aminocyclohexyl)oxy]pyridine-3-carboxylate2639407-98-8C13H18N2O3
- tert-Butyl 6-[(4-aminocyclohexyl)oxy]pyridine-3-carboxylate2639463-83-3C16H24N2O3
- tert-Butyl N-[(1r,4r)-4-[(3-cyanopyridin-2-yl)oxy]cyclohexyl]carbamate2680753-39-1C17H23N3O3
- 2-(Cyclohexyloxy)-4-iodo-5-methylpyridine3078387-39-7C12H16INO
- 5-Bromo-2-[(1-methylcyclohexyl)oxy]pyridine2300718-92-5C12H16BrNO
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cc2ccccc2)cc1952 chemicals
c1ccc(Oc2ccccc2)cc1933 chemicals
O=C(c1ccccc1)c1ccccc1537 chemicals
c1ccc(Nc2ccccc2)cc1395 chemicals
c1ccc(CN2CCCCC2)cc1283 chemicals
c1ccc(CN2CCNCC2)cc1267 chemicals
O=S(=O)(c1ccccc1)N1CCCCC1266 chemicals
c1ccc(Oc2ccccn2)cc1238 chemicals
c1ccc(Sc2ccccc2)cc1195 chemicals
O=S(=O)(c1ccccc1)N1CCNCC1195 chemicals
c1ccc(OC2CCCCO2)cc1164 chemicals
O=C(c1ccccc1)N1CCCCC1164 chemicals