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Murcko scaffold

1-(Thiophen-2-yl)piperidine scaffold

52 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
52
With full pages
4
Scaffold SMILES

c1csc(N2CCCCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Thiophen-2-yl)piperidine page
Murcko scaffold c1csc(N2CCCCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

5-(Piperidin-1-yl)thiophene-2-carbaldehyde chemical structure, C10H13NOS, CAS 24372-48-3
5-(Piperidin-1-yl)thiophene-2-carbaldehyde
CAS 24372-48-3C10H13NOS
5-(4-Hydroxypiperidin-1-yl)thiophene-2-carboxaldehyde chemical structure, C10H13NO2S, CAS 207290-72-0
5-(4-Hydroxypiperidin-1-yl)thiophene-2-carboxaldehyde
CAS 207290-72-0C10H13NO2S
Methyl 3-amino-4-cyano-5-(piperidin-1-yl)thiophene-2-carboxylate chemical structure, C12H15N3O2S, CAS 499771-09-4
Methyl 3-amino-4-cyano-5-(piperidin-1-yl)thiophene-2-carboxylate
CAS 499771-09-4C12H15N3O2S
4-Nitro-5-(1-piperidinyl)-2-thiophenesulfonamide chemical structure, C9H13N3O4S2, CAS 883002-58-2
4-Nitro-5-(1-piperidinyl)-2-thiophenesulfonamide
CAS 883002-58-2C9H13N3O4S2
1-[5-(1-Piperidyl)-2-thienyl]ethanone chemical structure, C11H15NOS, CAS 147688-75-3
1-[5-(1-Piperidyl)-2-thienyl]ethanone
CAS 147688-75-3C11H15NOS
1-(Thiophen-2-yl)piperidine chemical structure, C9H13NS, CAS 19983-20-1
1-(Thiophen-2-yl)piperidine
CAS 19983-20-1C9H13NS
Piperidine, 1-(3-nitro-2-thienyl)- chemical structure, C9H12N2O2S, CAS 2160-58-9
Piperidine, 1-(3-nitro-2-thienyl)-
CAS 2160-58-9C9H12N2O2S
4-Methyl-1-(5-nitrothiophen-2-yl)piperidine chemical structure, C10H14N2O2S, CAS 706767-26-2
4-Methyl-1-(5-nitrothiophen-2-yl)piperidine
CAS 706767-26-2C10H14N2O2S
3-Methyl-1-(5-nitrothiophen-2-yl)piperidine chemical structure, C10H14N2O2S, CAS 706767-29-5
3-Methyl-1-(5-nitrothiophen-2-yl)piperidine
CAS 706767-29-5C10H14N2O2S
Ethyl 1-(5-nitrothiophen-2-yl)piperidine-4-carboxylate chemical structure, C12H16N2O4S, CAS 706767-23-9
Ethyl 1-(5-nitrothiophen-2-yl)piperidine-4-carboxylate
CAS 706767-23-9C12H16N2O4S
3,5-Dimethyl-1-(5-nitrothiophen-2-yl)piperidine chemical structure, C11H16N2O2S, CAS 706767-38-6
3,5-Dimethyl-1-(5-nitrothiophen-2-yl)piperidine
CAS 706767-38-6C11H16N2O2S
N-Methyl-[(5-piperidinothien-2-yl)methyl]amine chemical structure, C11H18N2S, CAS 953409-06-8
N-Methyl-[(5-piperidinothien-2-yl)methyl]amine
CAS 953409-06-8C11H18N2S
1-(2-Thienyl)-4-piperidinecarboxylic acid chemical structure, C10H13NO2S, CAS 1104738-51-3
1-(2-Thienyl)-4-piperidinecarboxylic acid
CAS 1104738-51-3C10H13NO2S
5-Piperidin-1-ylthiophene-2-carbaldehyde oxime chemical structure, C10H14N2OS, CAS 1251409-07-0
5-Piperidin-1-ylthiophene-2-carbaldehyde oxime
CAS 1251409-07-0C10H14N2OS
1-(Thiophen-2-yl)piperidin-4-amine chemical structure, C9H14N2S, CAS 1248294-11-2
1-(Thiophen-2-yl)piperidin-4-amine
CAS 1248294-11-2C9H14N2S
5-[4-(Hydroxymethyl)piperidin-1-yl]thiophene-2-carbaldehyde chemical structure, C11H15NO2S, CAS 1342213-43-7
5-[4-(Hydroxymethyl)piperidin-1-yl]thiophene-2-carbaldehyde
CAS 1342213-43-7C11H15NO2S
5-(4-Methoxypiperidin-1-yl)thiophene-2-carbaldehyde chemical structure, C11H15NO2S, CAS 1341672-07-8
5-(4-Methoxypiperidin-1-yl)thiophene-2-carbaldehyde
CAS 1341672-07-8C11H15NO2S
5-[3-(Hydroxymethyl)piperidin-1-yl]thiophene-2-carbaldehyde chemical structure, C11H15NO2S, CAS 1338947-75-3
5-[3-(Hydroxymethyl)piperidin-1-yl]thiophene-2-carbaldehyde
CAS 1338947-75-3C11H15NO2S
5-(3-Hydroxypiperidin-1-yl)thiophene-2-carbaldehyde chemical structure, C10H13NO2S, CAS 1344203-08-2
5-(3-Hydroxypiperidin-1-yl)thiophene-2-carbaldehyde
CAS 1344203-08-2C10H13NO2S
1-(4-Methyl-5-nitro-2-thienyl)piperidine chemical structure, C10H14N2O2S, CAS 82834-50-2
1-(4-Methyl-5-nitro-2-thienyl)piperidine
CAS 82834-50-2C10H14N2O2S
{[5-(Piperidin-1-yl)thiophen-2-yl]methylidene}propanedinitrile chemical structure, C13H13N3S, CAS 344235-01-4
{[5-(Piperidin-1-yl)thiophen-2-yl]methylidene}propanedinitrile
CAS 344235-01-4C13H13N3S
5-(4-Hydroxy-4-methylpiperidin-1-yl)thiophene-2-carbaldehyde chemical structure, C11H15NO2S, CAS 1501207-95-9
5-(4-Hydroxy-4-methylpiperidin-1-yl)thiophene-2-carbaldehyde
CAS 1501207-95-9C11H15NO2S
1-(5-Bromothiophen-2-yl)piperidine chemical structure, C9H12BrNS, CAS 840464-73-5
1-(5-Bromothiophen-2-yl)piperidine
CAS 840464-73-5C9H12BrNS
[5-Acetyl-2-(4-methyl-1-piperidyl)-3-thienyl]azinic acid chemical structure, C12H16N2O3S, CAS 1708252-30-5
[5-Acetyl-2-(4-methyl-1-piperidyl)-3-thienyl]azinic acid
CAS 1708252-30-5C12H16N2O3S