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Murcko scaffold

N-Phenyl-2-{5-[(phenylcarbamoyl)amino]-1,3,4-thiadiazol-2-yl}acetamide scaffold

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
14
With full pages
5
Scaffold SMILES

O=C(Cc1nnc(NC(=O)Nc2ccccc2)s1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-{5-[(phenylcarbamoyl)amino]-1,3,4-thiadiazol-2-yl}acetamide page
Murcko scaffold O=C(Cc1nnc(NC(=O)Nc2ccccc2)s1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(5-{[(4-Methoxyphenyl)carbamoyl]amino}-1,3,4-thiadiazol-2-yl)-N-phenylacetamide chemical structure, C18H17N5O3S, CAS 426238-19-9
2-(5-{[(4-Methoxyphenyl)carbamoyl]amino}-1,3,4-thiadiazol-2-yl)-N-phenylacetamide
CAS 426238-19-9C18H17N5O3S
2-[5-[(4-Fluorophenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(3-methylphenyl)acetamide chemical structure, C18H16FN5O2S, CAS 426236-89-7
2-[5-[(4-Fluorophenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(3-methylphenyl)acetamide
CAS 426236-89-7C18H16FN5O2S
2-[5-[(4-Ethoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(4-methylphenyl)acetamide chemical structure, C20H21N5O3S, CAS 426241-92-1
2-[5-[(4-Ethoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(4-methylphenyl)acetamide
CAS 426241-92-1C20H21N5O3S
N-(3-Methylphenyl)-2-[5-[(4-methylphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C19H19N5O2S, CAS 426246-03-9
N-(3-Methylphenyl)-2-[5-[(4-methylphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]acetamide
CAS 426246-03-9C19H19N5O2S
2-[5-[(4-Methylphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-phenylacetamide chemical structure, C18H17N5O2S, CAS 426248-30-8
2-[5-[(4-Methylphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-phenylacetamide
CAS 426248-30-8C18H17N5O2S
N-(2-Methylphenyl)-2-[5-[(4-methylphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C19H19N5O2S, CAS 426238-77-9
N-(2-Methylphenyl)-2-[5-[(4-methylphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]acetamide
CAS 426238-77-9C19H19N5O2S
2-(5-{[(3,4-Dimethylphenyl)carbamoyl]amino}-1,3,4-thiadiazol-2-yl)-N-(2-methylphenyl)acetamide chemical structure, C20H21N5O2S, CAS 429625-10-5
2-(5-{[(3,4-Dimethylphenyl)carbamoyl]amino}-1,3,4-thiadiazol-2-yl)-N-(2-methylphenyl)acetamide
CAS 429625-10-5C20H21N5O2S
2-[5-[(4-Ethoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(3-methylphenyl)acetamide chemical structure, C20H21N5O3S, CAS 426249-91-4
2-[5-[(4-Ethoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(3-methylphenyl)acetamide
CAS 426249-91-4C20H21N5O3S
2-[5-[(4-Methoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(2-methylphenyl)acetamide chemical structure, C19H19N5O3S, CAS 426240-92-8
2-[5-[(4-Methoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(2-methylphenyl)acetamide
CAS 426240-92-8C19H19N5O3S
2-(5-{[(4-Fluorophenyl)carbamoyl]amino}-1,3,4-thiadiazol-2-yl)-N-phenylacetamide chemical structure, C17H14FN5O2S, CAS 426249-68-5
2-(5-{[(4-Fluorophenyl)carbamoyl]amino}-1,3,4-thiadiazol-2-yl)-N-phenylacetamide
CAS 426249-68-5C17H14FN5O2S
2-[5-[(4-Methoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(4-methylphenyl)acetamide chemical structure, C19H19N5O3S, CAS 426235-03-2
2-[5-[(4-Methoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(4-methylphenyl)acetamide
CAS 426235-03-2C19H19N5O3S
2-[5-[(4-Methoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(3-methylphenyl)acetamide chemical structure, C19H19N5O3S, CAS 426248-40-0
2-[5-[(4-Methoxyphenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(3-methylphenyl)acetamide
CAS 426248-40-0C19H19N5O3S
N-Phenyl-2-{5-[(phenylcarbamoyl)amino]-1,3,4-thiadiazol-2-yl}acetamide chemical structure, C17H15N5O2S, CAS 6074-24-4
N-Phenyl-2-{5-[(phenylcarbamoyl)amino]-1,3,4-thiadiazol-2-yl}acetamide
CAS 6074-24-4C17H15N5O2S
2-[5-[(4-Fluorophenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(2-methylphenyl)acetamide chemical structure, C18H16FN5O2S, CAS 426239-09-0
2-[5-[(4-Fluorophenyl)carbamoylamino]-1,3,4-thiadiazol-2-yl]-N-(2-methylphenyl)acetamide
CAS 426239-09-0C18H16FN5O2S