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Murcko scaffold

Ring system with 3 rings and 25 atoms

182 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
182
With full pages
11
Scaffold SMILES

O=C(Cc1csc(NC(=O)Nc2ccccc2)n1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1csc(NC(=O)Nc2ccccc2)n1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 182 chemicals

N-(2-Ethylphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O2S, CAS 921498-93-3
N-(2-Ethylphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921498-93-3C21H22N4O2S
N-(2-Ethylphenyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O2S, CAS 921466-45-7
N-(2-Ethylphenyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921466-45-7C21H22N4O2S
Methyl 4-[2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamido]benzoate chemical structure, C20H17ClN4O4S, CAS 897621-32-8
Methyl 4-[2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamido]benzoate
CAS 897621-32-8C20H17ClN4O4S
2-(2-{[(3-Chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-(3-fluoro-4-methylphenyl)acetamide chemical structure, C19H16ClFN4O2S, CAS 897621-44-2
2-(2-{[(3-Chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-(3-fluoro-4-methylphenyl)acetamide
CAS 897621-44-2C19H16ClFN4O2S
N-(4-Butylphenyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide chemical structure, C23H26N4O3S, CAS 897622-08-1
N-(4-Butylphenyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide
CAS 897622-08-1C23H26N4O3S
2-(2-{[(2-Methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C20H17F3N4O3S, CAS 897613-89-7
2-(2-{[(2-Methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-[4-(trifluoromethyl)phenyl]acetamide
CAS 897613-89-7C20H17F3N4O3S
2-(2-(3-(2-Methoxyphenyl)ureido)thiazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide chemical structure, C20H17F3N4O4S, CAS 897613-92-2
2-(2-(3-(2-Methoxyphenyl)ureido)thiazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide
CAS 897613-92-2C20H17F3N4O4S
N-[4-(Dimethylamino)phenyl]-2-(2-{[(2-methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide chemical structure, C21H23N5O3S, CAS 897613-93-3
N-[4-(Dimethylamino)phenyl]-2-(2-{[(2-methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide
CAS 897613-93-3C21H23N5O3S
Methyl 4-(2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamido)benzoate chemical structure, C21H20N4O5S, CAS 897613-94-4
Methyl 4-(2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamido)benzoate
CAS 897613-94-4C21H20N4O5S
N-(4-(Dimethylamino)phenyl)-2-(2-(3-phenylureido)thiazol-4-yl)acetamide chemical structure, C20H21N5O2S, CAS 921481-33-6
N-(4-(Dimethylamino)phenyl)-2-(2-(3-phenylureido)thiazol-4-yl)acetamide
CAS 921481-33-6C20H21N5O2S
N-(5-Chloro-2-methylphenyl)-2-(2-(3-phenylureido)thiazol-4-yl)acetamide chemical structure, C19H17ClN4O2S, CAS 921481-36-9
N-(5-Chloro-2-methylphenyl)-2-(2-(3-phenylureido)thiazol-4-yl)acetamide
CAS 921481-36-9C19H17ClN4O2S
N-(4-(Diethylamino)-2-methylphenyl)-2-(2-(3-phenylureido)thiazol-4-yl)acetamide chemical structure, C23H27N5O2S, CAS 921465-41-0
N-(4-(Diethylamino)-2-methylphenyl)-2-(2-(3-phenylureido)thiazol-4-yl)acetamide
CAS 921465-41-0C23H27N5O2S
N-Phenyl-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C19H18N4O2S, CAS 921481-53-0
N-Phenyl-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921481-53-0C19H18N4O2S
N-(o-Tolyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H20N4O2S, CAS 921484-00-6
N-(o-Tolyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921484-00-6C20H20N4O2S
N-(p-Tolyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H20N4O2S, CAS 921465-62-5
N-(p-Tolyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921465-62-5C20H20N4O2S
N-(4-Isopropylphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C22H24N4O2S, CAS 921481-55-2
N-(4-Isopropylphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921481-55-2C22H24N4O2S
N-(4-Butylphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C23H26N4O2S, CAS 1005299-59-1
N-(4-Butylphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 1005299-59-1C23H26N4O2S
N-(4-Chlorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C19H17ClN4O2S, CAS 921498-96-6
N-(4-Chlorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921498-96-6C19H17ClN4O2S
2-(2-(3-(p-Tolyl)ureido)thiazol-4-yl)-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C20H17F3N4O2S, CAS 921484-06-2
2-(2-(3-(p-Tolyl)ureido)thiazol-4-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 921484-06-2C20H17F3N4O2S
N-(4-Methoxyphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H20N4O3S, CAS 921498-99-9
N-(4-Methoxyphenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921498-99-9C20H20N4O3S
N-(4-(Dimethylamino)phenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H23N5O2S, CAS 921465-70-5
N-(4-(Dimethylamino)phenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921465-70-5C21H23N5O2S
N-(3,4-Dichlorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C19H16Cl2N4O2S, CAS 921499-08-3
N-(3,4-Dichlorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921499-08-3C19H16Cl2N4O2S
N-(3,4-Difluorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C19H16F2N4O2S, CAS 921465-76-1
N-(3,4-Difluorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921465-76-1C19H16F2N4O2S
N-(3-Chloro-4-fluorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C19H16ClFN4O2S, CAS 921484-18-6
N-(3-Chloro-4-fluorophenyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921484-18-6C19H16ClFN4O2S