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Murcko scaffold

Ring system with 2 rings and 20 atoms

31 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
31
With full pages
3
Scaffold SMILES

O=C(NCCCn1ccnc1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCCn1ccnc1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

N'-(4-Butoxyphenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C18H24N4O3, CAS 361463-63-0
N'-(4-Butoxyphenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 361463-63-0C18H24N4O3
N-(3-Imidazol-1-yl-propyl)-N'-(4-isopropyl-phenyl)-oxalamide chemical structure, C17H22N4O2, CAS 443669-35-0
N-(3-Imidazol-1-yl-propyl)-N'-(4-isopropyl-phenyl)-oxalamide
CAS 443669-35-0C17H22N4O2
N'-(4-Bromo-3-methylphenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C15H17BrN4O2, CAS 361463-61-8
N'-(4-Bromo-3-methylphenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 361463-61-8C15H17BrN4O2
N-(3-Imidazol-1-ylpropyl)-N'-(4-methoxyphenyl)oxamide chemical structure, C15H18N4O3, CAS 331759-25-2
N-(3-Imidazol-1-ylpropyl)-N'-(4-methoxyphenyl)oxamide
CAS 331759-25-2C15H18N4O3
N-(3,5-Dimethylphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]ethanediamide chemical structure, C16H20N4O2, CAS 384815-49-0
N-(3,5-Dimethylphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]ethanediamide
CAS 384815-49-0C16H20N4O2
N'-(4-Bromophenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C14H15BrN4O2, CAS 332404-19-0
N'-(4-Bromophenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 332404-19-0C14H15BrN4O2
N'-(4-Fluorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C14H15FN4O2, CAS 318258-79-6
N'-(4-Fluorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 318258-79-6C14H15FN4O2
N-(3-Imidazol-1-ylpropyl)-N'-(3-methylphenyl)oxamide chemical structure, C15H18N4O2, CAS 312286-92-3
N-(3-Imidazol-1-ylpropyl)-N'-(3-methylphenyl)oxamide
CAS 312286-92-3C15H18N4O2
N-(3,4-Dimethylphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]ethanediamide chemical structure, C16H20N4O2, CAS 294675-74-4
N-(3,4-Dimethylphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]ethanediamide
CAS 294675-74-4C16H20N4O2
N-(3-Imidazol-1-ylpropyl)-N'-(3-methoxyphenyl)oxamide chemical structure, C15H18N4O3, CAS 312501-75-0
N-(3-Imidazol-1-ylpropyl)-N'-(3-methoxyphenyl)oxamide
CAS 312501-75-0C15H18N4O3
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(2-methoxyphenyl)oxalamide chemical structure, C15H18N4O3, CAS 345366-86-1
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(2-methoxyphenyl)oxalamide
CAS 345366-86-1C15H18N4O3
N'-(2-Fluorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C14H15FN4O2, CAS 328091-04-9
N'-(2-Fluorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 328091-04-9C14H15FN4O2
N1-(3-(1H-Imidazol-1-yl)propyl)-N2-(2-methylphenyl)ethanediamide chemical structure, C15H18N4O2, CAS 333340-84-4
N1-(3-(1H-Imidazol-1-yl)propyl)-N2-(2-methylphenyl)ethanediamide
CAS 333340-84-4C15H18N4O2
N'-(2-Chlorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C14H15ClN4O2, CAS 385375-50-8
N'-(2-Chlorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 385375-50-8C14H15ClN4O2
N'-(3-Chloro-4-fluorophenyl)-N-[3-(2-methylimidazol-1-yl)propyl]oxamide chemical structure, C15H16ClFN4O2, CAS 728000-69-9
N'-(3-Chloro-4-fluorophenyl)-N-[3-(2-methylimidazol-1-yl)propyl]oxamide
CAS 728000-69-9C15H16ClFN4O2
N'-(3,5-Dichlorophenyl)-N-[3-(2-methylimidazol-1-yl)propyl]oxamide chemical structure, C15H16Cl2N4O2, CAS 728002-87-7
N'-(3,5-Dichlorophenyl)-N-[3-(2-methylimidazol-1-yl)propyl]oxamide
CAS 728002-87-7C15H16Cl2N4O2
N'-(4-Chlorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C14H15ClN4O2, CAS 898348-19-1
N'-(4-Chlorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 898348-19-1C14H15ClN4O2
N-(3-Imidazol-1-ylpropyl)-N'-(2-methoxy-5-methylphenyl)oxamide chemical structure, C16H20N4O3, CAS 899748-60-8
N-(3-Imidazol-1-ylpropyl)-N'-(2-methoxy-5-methylphenyl)oxamide
CAS 899748-60-8C16H20N4O3
N'-(3-Chloro-4-fluorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C14H14ClFN4O2, CAS 899748-81-3
N'-(3-Chloro-4-fluorophenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 899748-81-3C14H14ClFN4O2
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(3-fluoro-4-methylphenyl)oxalamide chemical structure, C15H17FN4O2, CAS 899956-52-6
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(3-fluoro-4-methylphenyl)oxalamide
CAS 899956-52-6C15H17FN4O2
Methyl 4-[[2-(3-imidazol-1-ylpropylamino)-2-oxoacetyl]amino]benzoate chemical structure, C16H18N4O4, CAS 922987-22-2
Methyl 4-[[2-(3-imidazol-1-ylpropylamino)-2-oxoacetyl]amino]benzoate
CAS 922987-22-2C16H18N4O4
N'-(3,4-Dimethoxyphenyl)-N-(3-imidazol-1-ylpropyl)oxamide chemical structure, C16H20N4O4, CAS 899749-01-0
N'-(3,4-Dimethoxyphenyl)-N-(3-imidazol-1-ylpropyl)oxamide
CAS 899749-01-0C16H20N4O4
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(5-chloro-2-methylphenyl)oxalamide chemical structure, C15H17ClN4O2, CAS 899749-08-7
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(5-chloro-2-methylphenyl)oxalamide
CAS 899749-08-7C15H17ClN4O2
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(2,6-dimethylphenyl)oxalamide chemical structure, C16H20N4O2, CAS 898374-90-8
N1-(3-(1H-imidazol-1-yl)propyl)-N2-(2,6-dimethylphenyl)oxalamide
CAS 898374-90-8C16H20N4O2