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Murcko scaffold

1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole scaffold

60 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
60
With full pages
5
Scaffold SMILES

c1cnn(CC2CCOC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole page
Murcko scaffold c1cnn(CC2CCOC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

1-((Oxolan-3-yl)methyl)-1H-pyrazol-5-amine chemical structure, C8H13N3O, CAS 1052564-96-1
1-((Oxolan-3-yl)methyl)-1H-pyrazol-5-amine
CAS 1052564-96-1C8H13N3O
4-Nitro-1-((tetrahydrofuran-3-yl)methyl)-1H-pyrazole chemical structure, C8H11N3O3, CAS 1172048-85-9
4-Nitro-1-((tetrahydrofuran-3-yl)methyl)-1H-pyrazole
CAS 1172048-85-9C8H11N3O3
1-(Oxolan-3-ylmethyl)pyrazole-4-ylamine chemical structure, C8H13N3O, CAS 1171662-77-3
1-(Oxolan-3-ylmethyl)pyrazole-4-ylamine
CAS 1171662-77-3C8H13N3O
4-Bromo-1-((oxolan-3-yl)methyl)-1H-pyrazole chemical structure, C8H11BrN2O, CAS 1247759-38-1
4-Bromo-1-((oxolan-3-yl)methyl)-1H-pyrazole
CAS 1247759-38-1C8H11BrN2O
2,2,2-Trifluoro-1-{1-[(oxolan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-one chemical structure, C10H11F3N2O2, CAS 1275320-15-4
2,2,2-Trifluoro-1-{1-[(oxolan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-one
CAS 1275320-15-4C10H11F3N2O2
3,5-Dimethyl-1-[(oxolan-3-yl)methyl]-1H-pyrazol-4-amine chemical structure, C10H17N3O, CAS 1248634-29-8
3,5-Dimethyl-1-[(oxolan-3-yl)methyl]-1H-pyrazol-4-amine
CAS 1248634-29-8C10H17N3O
1-((Oxolan-3-yl)methyl)-1H-pyrazol-3-amine chemical structure, C8H13N3O, CAS 1248173-28-5
1-((Oxolan-3-yl)methyl)-1H-pyrazol-3-amine
CAS 1248173-28-5C8H13N3O
4-Bromo-1-[(oxolan-3-yl)methyl]-1H-pyrazol-3-amine chemical structure, C8H12BrN3O, CAS 1250066-63-7
4-Bromo-1-[(oxolan-3-yl)methyl]-1H-pyrazol-3-amine
CAS 1250066-63-7C8H12BrN3O
3-Methyl-1-[(tetrahydro-3-furanyl)methyl]-1H-pyrazol-5-amine chemical structure, C9H15N3O, CAS 1248655-75-5
3-Methyl-1-[(tetrahydro-3-furanyl)methyl]-1H-pyrazol-5-amine
CAS 1248655-75-5C9H15N3O
4-Iodo-1-(oxolan-3-ylmethyl)-1H-pyrazol-5-amine chemical structure, C8H12IN3O, CAS 1247570-23-5
4-Iodo-1-(oxolan-3-ylmethyl)-1H-pyrazol-5-amine
CAS 1247570-23-5C8H12IN3O
(1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-yl)methanamine chemical structure, C9H15N3O, CAS 1339595-84-4
(1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-yl)methanamine
CAS 1339595-84-4C9H15N3O
1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole-4-carbaldehyde chemical structure, C9H12N2O2, CAS 1339517-49-5
1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole-4-carbaldehyde
CAS 1339517-49-5C9H12N2O2
1-(1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-yl)ethan-1-one chemical structure, C10H14N2O2, CAS 1340570-33-3
1-(1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-yl)ethan-1-one
CAS 1340570-33-3C10H14N2O2
Methyl({1-[(oxolan-3-yl)methyl]-1H-pyrazol-4-yl}methyl)amine chemical structure, C10H17N3O, CAS 1341175-70-9
Methyl({1-[(oxolan-3-yl)methyl]-1H-pyrazol-4-yl}methyl)amine
CAS 1341175-70-9C10H17N3O
(1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-yl)methanol chemical structure, C9H14N2O2, CAS 1341675-84-0
(1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-yl)methanol
CAS 1341675-84-0C9H14N2O2
2-{1-[(Oxolan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-amine chemical structure, C10H17N3O, CAS 1340106-14-0
2-{1-[(Oxolan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-amine
CAS 1340106-14-0C10H17N3O
1-{1-[(Oxolan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-amine chemical structure, C10H17N3O, CAS 1343972-10-0
1-{1-[(Oxolan-3-yl)methyl]-1H-pyrazol-4-yl}ethan-1-amine
CAS 1343972-10-0C10H17N3O
1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole chemical structure, C8H12N2O, CAS 1342444-71-6
1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole
CAS 1342444-71-6C8H12N2O
1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole-4-carboxylic acid chemical structure, C9H12N2O3, CAS 1341329-85-8
1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazole-4-carboxylic acid
CAS 1341329-85-8C9H12N2O3
4-Methyl-1-[(oxolan-3-yl)methyl]-1H-pyrazol-3-amine chemical structure, C9H15N3O, CAS 1341311-34-9
4-Methyl-1-[(oxolan-3-yl)methyl]-1H-pyrazol-3-amine
CAS 1341311-34-9C9H15N3O
4-Chloro-1-[(oxolan-3-yl)methyl]-1H-pyrazol-3-amine chemical structure, C8H12ClN3O, CAS 1343038-99-2
4-Chloro-1-[(oxolan-3-yl)methyl]-1H-pyrazol-3-amine
CAS 1343038-99-2C8H12ClN3O
4-Iodo-1-[(oxolan-3-yl)methyl]-1H-pyrazole chemical structure, C8H11IN2O, CAS 1341805-73-9
4-Iodo-1-[(oxolan-3-yl)methyl]-1H-pyrazole
CAS 1341805-73-9C8H11IN2O
3-tert-Butyl-1-((tetrahydrofuran-3-yl)methyl)-1H-pyrazol-5-amine chemical structure, C12H21N3O, CAS 1140918-64-4
3-tert-Butyl-1-((tetrahydrofuran-3-yl)methyl)-1H-pyrazol-5-amine
CAS 1140918-64-4C12H21N3O
4-Amino-1-[(oxolan-3-yl)methyl]-1H-pyrazole-3-carboxamide chemical structure, C9H14N4O2, CAS 1287670-47-6
4-Amino-1-[(oxolan-3-yl)methyl]-1H-pyrazole-3-carboxamide
CAS 1287670-47-6C9H14N4O2