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Murcko scaffold

5-Benzylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-dione scaffold

65 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
65
With full pages
15
Scaffold SMILES

O=C1NC(=S)NC(=O)C1=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Benzylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-dione page
Murcko scaffold O=C1NC(=S)NC(=O)C1=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

5-(4-Chloro-benzylidene)-2-thioxo-dihydro-pyrimidine-4,6-dione chemical structure, C11H7ClN2O2S, CAS 27430-13-3
5-(4-Chloro-benzylidene)-2-thioxo-dihydro-pyrimidine-4,6-dione
CAS 27430-13-3C11H7ClN2O2S
5-[(4-Fluorophenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C11H7FN2O2S, CAS 92754-58-0
5-[(4-Fluorophenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 92754-58-0C11H7FN2O2S
5-[(4-Nitrophenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C11H7N3O4S, CAS 27430-12-2
5-[(4-Nitrophenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 27430-12-2C11H7N3O4S
4,6(1H,5H)-Pyrimidinedione, dihydro-5-((4-methoxyphenyl)methylene)-2-thioxo- chemical structure, C12H10N2O3S, CAS 60045-61-6
4,6(1H,5H)-Pyrimidinedione, dihydro-5-((4-methoxyphenyl)methylene)-2-thioxo-
CAS 60045-61-6C12H10N2O3S
RefChem:357078 chemical structure, C15H17N3O2S, CAS 60045-59-2
RefChem:357078
CAS 60045-59-2C15H17N3O2S
5-(4-Methylbenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C12H10N2O2S, CAS 60045-62-7
5-(4-Methylbenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
CAS 60045-62-7C12H10N2O2S
5-(4-Bromo-benzylidene)-2-thioxo-dihydro-pyrimidine-4,6-dione chemical structure, C11H7BrN2O2S, CAS 27430-14-4
5-(4-Bromo-benzylidene)-2-thioxo-dihydro-pyrimidine-4,6-dione
CAS 27430-14-4C11H7BrN2O2S
5-[(2,4-Dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C13H12N2O4S, CAS 62581-41-3
5-[(2,4-Dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 62581-41-3C13H12N2O4S
5-(2-Methoxybenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C12H10N2O3S, CAS 202063-67-0
5-(2-Methoxybenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
CAS 202063-67-0C12H10N2O3S
5-(2,6-Dichlorobenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione chemical structure, C11H6Cl2N2O2S, CAS 260410-67-1
5-(2,6-Dichlorobenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
CAS 260410-67-1C11H6Cl2N2O2S
5-[(2,4-Dimethoxyphenyl)methylidene]-1,3-diethyl-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C17H20N2O4S, CAS 5799-86-0
5-[(2,4-Dimethoxyphenyl)methylidene]-1,3-diethyl-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 5799-86-0C17H20N2O4S
5-(2,3-Dimethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione chemical structure, C13H12N2O4S, CAS 260410-15-9
5-(2,3-Dimethoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
CAS 260410-15-9C13H12N2O4S
5-Benzylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C11H8N2O2S, CAS 27470-61-7
5-Benzylidene-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
CAS 27470-61-7C11H8N2O2S
4,6(1H,5H)-Pyrimidinedione, 5-[(2,4-diethoxyphenyl)methylene]dihydro-1,3-dimethyl-2-thioxo- chemical structure, C17H20N2O4S, CAS 636-36-2
4,6(1H,5H)-Pyrimidinedione, 5-[(2,4-diethoxyphenyl)methylene]dihydro-1,3-dimethyl-2-thioxo-
CAS 636-36-2C17H20N2O4S
4,5-Dimethylaminobenzylidene-2-thiobarbituric acid chemical structure, C13H13N3O2S, CAS 27430-15-5
4,5-Dimethylaminobenzylidene-2-thiobarbituric acid
CAS 27430-15-5C13H13N3O2S
2-Thioxo-5-(3,4,5-trimethoxybenzylidene)hexahydropyrimidine-4,6-dione chemical structure, C14H14N2O5S, CAS 49581-13-7
2-Thioxo-5-(3,4,5-trimethoxybenzylidene)hexahydropyrimidine-4,6-dione
CAS 49581-13-7C14H14N2O5S
5-((3,4-Dimethoxyphenyl)methylidene)-4,6-dihydroxypyrimidine-2(5H)-thione chemical structure, C13H12N2O4S, CAS 60045-60-5
5-((3,4-Dimethoxyphenyl)methylidene)-4,6-dihydroxypyrimidine-2(5H)-thione
CAS 60045-60-5C13H12N2O4S
5-(3-Nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione chemical structure, C11H7N3O4S, CAS 60045-64-9
5-(3-Nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
CAS 60045-64-9C11H7N3O4S
1,3-Diethyl-5-(2-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione chemical structure, C16H18N2O3S, CAS 352348-64-2
1,3-Diethyl-5-(2-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
CAS 352348-64-2C16H18N2O3S
2-Sulfanylidene-5-[(2,3,4-trimethoxyphenyl)methylidene]-1,3-diazinane-4,6-dione chemical structure, C14H14N2O5S, CAS 301351-66-6
2-Sulfanylidene-5-[(2,3,4-trimethoxyphenyl)methylidene]-1,3-diazinane-4,6-dione
CAS 301351-66-6C14H14N2O5S
(5Z)-5-[(2,3-Dimethoxyphenyl)methylidene]-1-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H16N2O4S, CAS 347394-85-8
(5Z)-5-[(2,3-Dimethoxyphenyl)methylidene]-1-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 347394-85-8C16H16N2O4S
(5Z)-5-[(3-Methoxyphenyl)methylidene]-1-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C15H14N2O3S, CAS 347394-92-7
(5Z)-5-[(3-Methoxyphenyl)methylidene]-1-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 347394-92-7C15H14N2O3S
(5Z)-5-[(2-Ethoxyphenyl)methylidene]-1-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione chemical structure, C16H16N2O3S, CAS 347394-96-1
(5Z)-5-[(2-Ethoxyphenyl)methylidene]-1-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
CAS 347394-96-1C16H16N2O3S
5-(2-Bromo-5-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione chemical structure, C12H9BrN2O3S, CAS 353768-74-8
5-(2-Bromo-5-methoxybenzylidene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
CAS 353768-74-8C12H9BrN2O3S