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Murcko scaffold

Pyrido[3,4-b]pyrazine scaffold

92 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
92
With full pages
10
Scaffold SMILES

c1cc2nccnc2cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrido[3,4-b]pyrazine page
Murcko scaffold c1cc2nccnc2cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 92 chemicals

3-Methylpyrido[3,4-b]pyrazine-5,7-diamine chemical structure, C8H9N5, CAS 74023-40-8
3-Methylpyrido[3,4-b]pyrazine-5,7-diamine
CAS 74023-40-8C8H9N5
2-Methylpyrido[3,4-b]pyrazine-5,7-diamine chemical structure, C8H9N5, CAS 16335-90-3
2-Methylpyrido[3,4-b]pyrazine-5,7-diamine
CAS 16335-90-3C8H9N5
2-Chloro-5-[[4-[diethylamino]-1-methylbutyl]amino]pyrido[3,4-b]pyrazine chemical structure, C16H24ClN5, CAS 30146-52-2
2-Chloro-5-[[4-[diethylamino]-1-methylbutyl]amino]pyrido[3,4-b]pyrazine
CAS 30146-52-2C16H24ClN5
2,3-Dimethylpyrido[3,4-b]pyrazine chemical structure, C9H9N3, CAS 34154-05-7
2,3-Dimethylpyrido[3,4-b]pyrazine
CAS 34154-05-7C9H9N3
Pyrido[3,4-b]pyrazine chemical structure, C7H5N3, CAS 254-86-4
Pyrido[3,4-b]pyrazine
CAS 254-86-4C7H5N3
5-Chloropyrido[4,3-b]pyrazine chemical structure, C7H4ClN3, CAS 214045-82-6
5-Chloropyrido[4,3-b]pyrazine
CAS 214045-82-6C7H4ClN3
5-Chloro-2,3-dimethylpyrido[3,4-b]pyrazine chemical structure, C9H8ClN3, CAS 384844-04-6
5-Chloro-2,3-dimethylpyrido[3,4-b]pyrazine
CAS 384844-04-6C9H8ClN3
5-Chloro-2-methylpyrido(3,4-b)pyrazine chemical structure, C8H6ClN3, CAS 556053-82-8
5-Chloro-2-methylpyrido(3,4-b)pyrazine
CAS 556053-82-8C8H6ClN3
Pyrido[3,4-b]pyrazine, 2-(trifluoromethyl)- chemical structure, C8H4F3N3, CAS 115652-66-9
Pyrido[3,4-b]pyrazine, 2-(trifluoromethyl)-
CAS 115652-66-9C8H4F3N3
8-Bromopyrido(3,4-b)pyrazine chemical structure, C7H4BrN3, CAS 929074-45-3
8-Bromopyrido(3,4-b)pyrazine
CAS 929074-45-3C7H4BrN3
8-Chloropyrido[3,4-b]pyrazine chemical structure, C7H4ClN3, CAS 929074-47-5
8-Chloropyrido[3,4-b]pyrazine
CAS 929074-47-5C7H4ClN3
2,3-Dichloropyrido[3,4-b]pyrazine chemical structure, C7H3Cl2N3, CAS 35251-99-1
2,3-Dichloropyrido[3,4-b]pyrazine
CAS 35251-99-1C7H3Cl2N3
4-N-(8-Bromo-2-chloropyrido[3,4-b]pyrazin-5-yl)-1-N,1-N-diethylpentane-1,4-diamine, hydrochloride chemical structure, C16H24BrCl2N5, CAS 30146-53-3
4-N-(8-Bromo-2-chloropyrido[3,4-b]pyrazin-5-yl)-1-N,1-N-diethylpentane-1,4-diamine, hydrochloride
CAS 30146-53-3C16H24BrCl2N5
Pyrido[3,4-b]pyrazine-8-carboxylic acid chemical structure, C8H5N3O2, CAS 1023815-46-4
Pyrido[3,4-b]pyrazine-8-carboxylic acid
CAS 1023815-46-4C8H5N3O2
7-Chloropyrido[3,4-b]pyrazine chemical structure, C7H4ClN3, CAS 93049-39-9
7-Chloropyrido[3,4-b]pyrazine
CAS 93049-39-9C7H4ClN3
Pyrido[3,4-b]pyrazin-7-amine chemical structure, C7H6N4, CAS 91673-74-4
Pyrido[3,4-b]pyrazin-7-amine
CAS 91673-74-4C7H6N4
2-Methylpyrido[3,4-b]pyrazine chemical structure, C8H7N3, CAS 51208-84-5
2-Methylpyrido[3,4-b]pyrazine
CAS 51208-84-5C8H7N3
3-Methylpyrido[3,4-b]pyrazine chemical structure, C8H7N3, CAS 700-80-1
3-Methylpyrido[3,4-b]pyrazine
CAS 700-80-1C8H7N3
Pyrido[3,4-b]pyrazin-8-amine chemical structure, C7H6N4, CAS 120208-34-6
Pyrido[3,4-b]pyrazin-8-amine
CAS 120208-34-6C7H6N4
Pyrido(3,4-b)pyrazin-5-amine chemical structure, C7H6N4, CAS 859295-23-1
Pyrido(3,4-b)pyrazin-5-amine
CAS 859295-23-1C7H6N4
(2-Methylpyrido[3,4-b]pyrazin-5-yl)hydrazine chemical structure, C8H9N5, CAS 877402-60-3
(2-Methylpyrido[3,4-b]pyrazin-5-yl)hydrazine
CAS 877402-60-3C8H9N5
(3-Methylpyrido[3,4-b]pyrazin-5-yl)hydrazine chemical structure, C8H9N5, CAS 877402-61-4
(3-Methylpyrido[3,4-b]pyrazin-5-yl)hydrazine
CAS 877402-61-4C8H9N5
2,3-Dimethylpyrido[3,4-B]pyrazin-8-amine chemical structure, C9H10N4, CAS 109868-80-6
2,3-Dimethylpyrido[3,4-B]pyrazin-8-amine
CAS 109868-80-6C9H10N4
[2-(Trifluoromethyl)pyrido[3,4-b]pyrazin-5-yl]hydrazine chemical structure, C8H6F3N5, CAS 877402-70-5
[2-(Trifluoromethyl)pyrido[3,4-b]pyrazin-5-yl]hydrazine
CAS 877402-70-5C8H6F3N5