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Murcko scaffold

Ring system with 3 rings and 14 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
16
With full pages
4
Scaffold SMILES

c1coc(-c2ccc3cn[nH]c3n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1coc(-c2ccc3cn[nH]c3n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

6-(Furan-2-yl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H13N3O3, CAS 900137-06-6
6-(Furan-2-yl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 900137-06-6C14H13N3O3
6-(Furan-2-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C13H11N3O3, CAS 893645-73-3
6-(Furan-2-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 893645-73-3C13H11N3O3
6-(2-Furanyl)-1-(2-methylpropyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C15H15N3O3, CAS 953746-84-4
6-(2-Furanyl)-1-(2-methylpropyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 953746-84-4C15H15N3O3
1-Ethyl-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C13H11N3O3, CAS 954266-84-3
1-Ethyl-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 954266-84-3C13H11N3O3
6-(2-Furanyl)-1-(2-hydroxyethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H13N3O4, CAS 954578-00-8
6-(2-Furanyl)-1-(2-hydroxyethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 954578-00-8C14H13N3O4
6-(2-Furyl)-1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo(3,4-B)pyridine chemical structure, C13H10F3N3O, CAS 834896-55-8
6-(2-Furyl)-1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo(3,4-B)pyridine
CAS 834896-55-8C13H10F3N3O
Methyl 6-(furan-2-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C14H13N3O3, CAS 834896-23-0
Methyl 6-(furan-2-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 834896-23-0C14H13N3O3
Ethyl 2-(4-(difluoromethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate chemical structure, C16H15F2N3O3, CAS 1011373-83-3
Ethyl 2-(4-(difluoromethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate
CAS 1011373-83-3C16H15F2N3O3
Methyl 1-(2-ethoxy-2-oxoethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C17H17N3O5, CAS 1011398-34-7
Methyl 1-(2-ethoxy-2-oxoethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1011398-34-7C17H17N3O5
6-(Furan-2-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide chemical structure, C13H13N5O2, CAS 937598-55-5
6-(Furan-2-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide
CAS 937598-55-5C13H13N5O2
2-[6-(2-Furyl)-3-methyl-4-(trifluoromethyl)pyrazolo[3,4-b]pyridin-1-yl]acetic acid chemical structure, C14H10F3N3O3, CAS 937605-78-2
2-[6-(2-Furyl)-3-methyl-4-(trifluoromethyl)pyrazolo[3,4-b]pyridin-1-yl]acetic acid
CAS 937605-78-2C14H10F3N3O3
2-(4-(Difluoromethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid chemical structure, C14H11F2N3O3, CAS 937607-10-8
2-(4-(Difluoromethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
CAS 937607-10-8C14H11F2N3O3
1-(Carboxymethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H11N3O5, CAS 1011400-21-7
1-(Carboxymethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011400-21-7C14H11N3O5
Methyl 1-(2-cyanoethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C16H14N4O3, CAS 1018141-90-6
Methyl 1-(2-cyanoethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018141-90-6C16H14N4O3
Methyl 1-ethyl-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C14H13N3O3, CAS 1018144-36-9
Methyl 1-ethyl-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1018144-36-9C14H13N3O3
6-(Furan-2-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine chemical structure, C12H8F3N3O, CAS 1011389-96-0
6-(Furan-2-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine
CAS 1011389-96-0C12H8F3N3O