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Murcko scaffold

1-(Phenylacetyl)pyrrolidine scaffold

184 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
184
With full pages
1
Scaffold SMILES

O=C(Cc1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Phenylacetyl)pyrrolidine page
Murcko scaffold O=C(Cc1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 184 chemicals

1-(2-Phenylacetyl)-L-prolylglycine ethy ester chemical structure, C17H22N2O4, CAS 157115-85-0
1-(2-Phenylacetyl)-L-prolylglycine ethy ester
CAS 157115-85-0C17H22N2O4
Diethyl 5-hydroxy-1-[2-(2-nitrophenyl)acetyl]pyrrolidine-2,2-dicarboxylate chemical structure, C18H22N2O8, CAS 66709-35-1
Diethyl 5-hydroxy-1-[2-(2-nitrophenyl)acetyl]pyrrolidine-2,2-dicarboxylate
CAS 66709-35-1C18H22N2O8
2-(4-Methoxyphenyl)-1-pyrrolidin-1-ylethanone chemical structure, C13H17NO2, CAS 123902-08-9
2-(4-Methoxyphenyl)-1-pyrrolidin-1-ylethanone
CAS 123902-08-9C13H17NO2
2-(4-Bromophenyl)-1-(pyrrolidin-1-yl)ethanone chemical structure, C12H14BrNO, CAS 13734-66-2
2-(4-Bromophenyl)-1-(pyrrolidin-1-yl)ethanone
CAS 13734-66-2C12H14BrNO
(2S)-1-(2-Phenylacetyl)pyrrolidine-2-carboxylic acid chemical structure, C13H15NO3, CAS 2752-38-7
(2S)-1-(2-Phenylacetyl)pyrrolidine-2-carboxylic acid
CAS 2752-38-7C13H15NO3
2-(4-Fluorophenyl)-1-pyrrolidin-1-ylethanone chemical structure, C12H14FNO, CAS 433234-09-4
2-(4-Fluorophenyl)-1-pyrrolidin-1-ylethanone
CAS 433234-09-4C12H14FNO
1-[(4-Nitrophenyl)acetyl]pyrrolidine chemical structure, C12H14N2O3, CAS 168897-62-9
1-[(4-Nitrophenyl)acetyl]pyrrolidine
CAS 168897-62-9C12H14N2O3
2-Phenyl-1-pyrrolidinylbutan-1-one chemical structure, C14H19NO, CAS 101114-01-6
2-Phenyl-1-pyrrolidinylbutan-1-one
CAS 101114-01-6C14H19NO
Dopamine, lys-pro-amide- chemical structure, C19H28N4O5, CAS 117992-60-6
Dopamine, lys-pro-amide-
CAS 117992-60-6C19H28N4O5
Dopamine, gly-pro-amide- chemical structure, C15H19N3O5, CAS 117992-61-7
Dopamine, gly-pro-amide-
CAS 117992-61-7C15H19N3O5
1-(Phenylacetyl)pyrrolidine chemical structure, C12H15NO, CAS 3389-53-5
1-(Phenylacetyl)pyrrolidine
CAS 3389-53-5C12H15NO
1-[(Acetyloxy)phenylacetyl]-pyrrolidine chemical structure, C14H17NO3, CAS 73200-21-2
1-[(Acetyloxy)phenylacetyl]-pyrrolidine
CAS 73200-21-2C14H17NO3
2-Chloro-2-phenyl-1-(pyrrolidin-1-yl)ethan-1-one chemical structure, C12H14ClNO, CAS 190964-87-5
2-Chloro-2-phenyl-1-(pyrrolidin-1-yl)ethan-1-one
CAS 190964-87-5C12H14ClNO
2-(3,4-Dimethoxyphenyl)-1-(1-pyrrolidinyl)ethanone chemical structure, C14H19NO3, CAS 73252-02-5
2-(3,4-Dimethoxyphenyl)-1-(1-pyrrolidinyl)ethanone
CAS 73252-02-5C14H19NO3
2-(4-Chlorophenyl)-1-(pyrrolidin-1-yl)ethan-1-one chemical structure, C12H14ClNO, CAS 19202-19-8
2-(4-Chlorophenyl)-1-(pyrrolidin-1-yl)ethan-1-one
CAS 19202-19-8C12H14ClNO
2-(2-Methylphenyl)-1-pyrrolidin-1-ylethanone chemical structure, C13H17NO, CAS 512787-29-0
2-(2-Methylphenyl)-1-pyrrolidin-1-ylethanone
CAS 512787-29-0C13H17NO
2-(2,4-Dimethoxyphenyl)-1-pyrrolidin-1-ylethanone chemical structure, C14H19NO3, CAS 923225-75-6
2-(2,4-Dimethoxyphenyl)-1-pyrrolidin-1-ylethanone
CAS 923225-75-6C14H19NO3
(2S)-1-[(2R)-2-Phenylpropanoyl]pyrrolidine-2-carboxylic acid chemical structure, C14H17NO3, CAS 146622-06-2
(2S)-1-[(2R)-2-Phenylpropanoyl]pyrrolidine-2-carboxylic acid
CAS 146622-06-2C14H17NO3
Glycine, N-[1-(phenylacetyl)-L-prolyl]- chemical structure, C15H18N2O4, CAS 157115-95-2
Glycine, N-[1-(phenylacetyl)-L-prolyl]-
CAS 157115-95-2C15H18N2O4
6-Amino-N-[1-(2-phenylacetyl)-3-pyrrolidinyl]hexanamide chemical structure, C18H27N3O2, CAS 727720-02-7
6-Amino-N-[1-(2-phenylacetyl)-3-pyrrolidinyl]hexanamide
CAS 727720-02-7C18H27N3O2
4-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-benzonitrile chemical structure, C13H14N2O, CAS 79149-49-8
4-(2-Oxo-2-pyrrolidin-1-yl-ethyl)-benzonitrile
CAS 79149-49-8C13H14N2O
2-Phenyl-1-(pyrrolidin-1-yl)propan-1-one chemical structure, C13H17NO, CAS 74931-56-9
2-Phenyl-1-(pyrrolidin-1-yl)propan-1-one
CAS 74931-56-9C13H17NO
2-(4-Hydroxyphenyl)-1-(pyrrolidin-1-yl)ethan-1-one chemical structure, C12H15NO2, CAS 78190-31-5
2-(4-Hydroxyphenyl)-1-(pyrrolidin-1-yl)ethan-1-one
CAS 78190-31-5C12H15NO2
1-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-phenylethan-1-one chemical structure, C13H17NO2, CAS 124932-17-8
1-[2-(Hydroxymethyl)pyrrolidin-1-yl]-2-phenylethan-1-one
CAS 124932-17-8C13H17NO2