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Murcko scaffold

Ring system with 2 rings and 13 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(Nc1ccsc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccsc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Methyl 3-{[(3-methyl-2-thienyl)carbonyl]amino}-2-thiophenecarboxylate chemical structure, C12H11NO3S2, CAS 293327-16-9
Methyl 3-{[(3-methyl-2-thienyl)carbonyl]amino}-2-thiophenecarboxylate
CAS 293327-16-9C12H11NO3S2
Methyl 3-(5-bromothiophene-2-carboxamido)thiophene-2-carboxylate chemical structure, C11H8BrNO3S2, CAS 717866-86-9
Methyl 3-(5-bromothiophene-2-carboxamido)thiophene-2-carboxylate
CAS 717866-86-9C11H8BrNO3S2
Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}thiophene-2-carboxylate chemical structure, C11H8ClNO3S2, CAS 717869-08-4
Methyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}thiophene-2-carboxylate
CAS 717869-08-4C11H8ClNO3S2
Methyl 3-(2-thienylcarbonylamino)thiophene-2-carboxylate chemical structure, C11H9NO3S2, CAS 545351-07-3
Methyl 3-(2-thienylcarbonylamino)thiophene-2-carboxylate
CAS 545351-07-3C11H9NO3S2
3-{[(5-Chloro-2-thienyl)carbonyl]amino}thiophene-2-carboxylic acid chemical structure, C10H6ClNO3S2, CAS 929214-78-8
3-{[(5-Chloro-2-thienyl)carbonyl]amino}thiophene-2-carboxylic acid
CAS 929214-78-8C10H6ClNO3S2
4-{[(5-Chloro-2-thienyl)carbonyl]amino}thiophene-3-carboxylic acid chemical structure, C10H6ClNO3S2, CAS 929214-73-3
4-{[(5-Chloro-2-thienyl)carbonyl]amino}thiophene-3-carboxylic acid
CAS 929214-73-3C10H6ClNO3S2
Methyl 4-{[(5-chloro-2-thienyl)-carbonyl]amino}thiophene-3-carboxylate chemical structure, C11H8ClNO3S2, CAS 929214-74-4
Methyl 4-{[(5-chloro-2-thienyl)-carbonyl]amino}thiophene-3-carboxylate
CAS 929214-74-4C11H8ClNO3S2
N-(2,4-Dimethylthiophen-3-yl)thiophene-2-carboxamide chemical structure, C11H11NOS2, CAS 87675-90-9
N-(2,4-Dimethylthiophen-3-yl)thiophene-2-carboxamide
CAS 87675-90-9C11H11NOS2