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Murcko scaffold

Ring system with 2 rings and 18 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
8
With full pages
7
Scaffold SMILES

O=C(Cc1ccccc1)NNC(=O)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NNC(=O)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N'-[2-(4-Methoxyphenyl)acetyl]-2-thiophenecarbohydrazide chemical structure, C14H14N2O3S, CAS 308293-95-0
N'-[2-(4-Methoxyphenyl)acetyl]-2-thiophenecarbohydrazide
CAS 308293-95-0C14H14N2O3S
5-Bromo-N'-[2-(3,4-dimethoxyphenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C15H15BrN2O4S, CAS 853593-76-7
5-Bromo-N'-[2-(3,4-dimethoxyphenyl)acetyl]thiophene-2-carbohydrazide
CAS 853593-76-7C15H15BrN2O4S
N'-[2-(2-Chloro-6-fluorophenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C13H10ClFN2O2S, CAS 853725-75-4
N'-[2-(2-Chloro-6-fluorophenyl)acetyl]thiophene-2-carbohydrazide
CAS 853725-75-4C13H10ClFN2O2S
N'-[2-(2-Fluorophenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C13H11FN2O2S, CAS 847791-83-7
N'-[2-(2-Fluorophenyl)acetyl]thiophene-2-carbohydrazide
CAS 847791-83-7C13H11FN2O2S
N'-[2-(4-Bromophenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C13H11BrN2O2S, CAS 847791-84-8
N'-[2-(4-Bromophenyl)acetyl]thiophene-2-carbohydrazide
CAS 847791-84-8C13H11BrN2O2S
5-Bromo-N'-[2-(2-chloro-6-fluorophenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C13H9BrClFN2O2S, CAS 853584-96-0
5-Bromo-N'-[2-(2-chloro-6-fluorophenyl)acetyl]thiophene-2-carbohydrazide
CAS 853584-96-0C13H9BrClFN2O2S
N'-[2-(3,4,5-Trimethoxyphenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C16H18N2O5S, CAS 863420-24-0
N'-[2-(3,4,5-Trimethoxyphenyl)acetyl]thiophene-2-carbohydrazide
CAS 863420-24-0C16H18N2O5S
N'-[2-(2-Nitrophenyl)acetyl]thiophene-2-carbohydrazide chemical structure, C13H11N3O4S, CAS 863420-26-2
N'-[2-(2-Nitrophenyl)acetyl]thiophene-2-carbohydrazide
CAS 863420-26-2C13H11N3O4S