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Murcko scaffold

5-(3-Thienyl)-1H-pyrazole scaffold

435 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
435
With full pages
6
Scaffold SMILES

c1cc(-c2ccsc2)[nH]n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(3-Thienyl)-1H-pyrazole page
Murcko scaffold c1cc(-c2ccsc2)[nH]n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 435 chemicals

3-Methyl-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic acid chemical structure, C10H10N2O2S, CAS 1047636-30-5
3-Methyl-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic acid
CAS 1047636-30-5C10H10N2O2S
5-(2,5-Dimethyl-3-thienyl)-1H-pyrazole-3-carboxamide chemical structure, C10H11N3OS, CAS 1636877-21-8
5-(2,5-Dimethyl-3-thienyl)-1H-pyrazole-3-carboxamide
CAS 1636877-21-8C10H11N3OS
1-Methyl-4-propyl-3-(thiophen-3-yl)-1H-pyrazol-5-amine chemical structure, C11H15N3S, CAS 1174306-32-1
1-Methyl-4-propyl-3-(thiophen-3-yl)-1H-pyrazol-5-amine
CAS 1174306-32-1C11H15N3S
N-Methyl-1-(3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C9H11N3S, CAS 1506070-59-2
N-Methyl-1-(3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine
CAS 1506070-59-2C9H11N3S
(1-Methyl-3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C9H11N3S, CAS 1499998-80-9
(1-Methyl-3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine
CAS 1499998-80-9C9H11N3S
N-Methyl-1-(1-methyl-3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C10H13N3S, CAS 1542092-08-9
N-Methyl-1-(1-methyl-3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine
CAS 1542092-08-9C10H13N3S
(3-(Thiophen-3-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C8H9N3S, CAS 1518226-53-3
(3-(Thiophen-3-yl)-1H-pyrazol-4-yl)methanamine
CAS 1518226-53-3C8H9N3S
3-(5-Iodothiophen-3-yl)-1,4-dimethyl-1H-pyrazol-5-amine chemical structure, C9H10IN3S, CAS 1526536-89-9
3-(5-Iodothiophen-3-yl)-1,4-dimethyl-1H-pyrazol-5-amine
CAS 1526536-89-9C9H10IN3S
3-(5-Iodothiophen-3-yl)-1-methyl-1H-pyrazol-5-amine chemical structure, C8H8IN3S, CAS 1535369-31-3
3-(5-Iodothiophen-3-yl)-1-methyl-1H-pyrazol-5-amine
CAS 1535369-31-3C8H8IN3S
2-(5-Amino-3-(5-iodothiophen-3-yl)-1H-pyrazol-1-yl)ethan-1-ol chemical structure, C9H10IN3OS, CAS 1517932-50-1
2-(5-Amino-3-(5-iodothiophen-3-yl)-1H-pyrazol-1-yl)ethan-1-ol
CAS 1517932-50-1C9H10IN3OS
4-Ethyl-3-(5-iodothiophen-3-yl)-1-methyl-1H-pyrazol-5-amine chemical structure, C10H12IN3S, CAS 1541153-86-9
4-Ethyl-3-(5-iodothiophen-3-yl)-1-methyl-1H-pyrazol-5-amine
CAS 1541153-86-9C10H12IN3S
1,4-Dimethyl-3-(4-methylthiophen-3-yl)-1H-pyrazol-5-amine chemical structure, C10H13N3S, CAS 1501500-01-1
1,4-Dimethyl-3-(4-methylthiophen-3-yl)-1H-pyrazol-5-amine
CAS 1501500-01-1C10H13N3S
1-Methyl-3-(4-methylthiophen-3-yl)-1H-pyrazol-5-amine chemical structure, C9H11N3S, CAS 1519940-05-6
1-Methyl-3-(4-methylthiophen-3-yl)-1H-pyrazol-5-amine
CAS 1519940-05-6C9H11N3S
2-[5-Amino-3-(4-methylthiophen-3-yl)-1H-pyrazol-1-yl]ethan-1-ol chemical structure, C10H13N3OS, CAS 1512818-58-4
2-[5-Amino-3-(4-methylthiophen-3-yl)-1H-pyrazol-1-yl]ethan-1-ol
CAS 1512818-58-4C10H13N3OS
4-Ethyl-1-methyl-3-(4-methylthiophen-3-yl)-1H-pyrazol-5-amine chemical structure, C11H15N3S, CAS 1526284-21-8
4-Ethyl-1-methyl-3-(4-methylthiophen-3-yl)-1H-pyrazol-5-amine
CAS 1526284-21-8C11H15N3S
(1-Ethyl-3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine chemical structure, C10H13N3S, CAS 1509674-35-4
(1-Ethyl-3-(thiophen-3-yl)-1H-pyrazol-4-yl)methanamine
CAS 1509674-35-4C10H13N3S
N-{2-[3-(Thiophen-3-yl)-1H-pyrazol-1-yl]ethyl}acetamide chemical structure, C11H13N3OS, CAS 2034477-68-2
N-{2-[3-(Thiophen-3-yl)-1H-pyrazol-1-yl]ethyl}acetamide
CAS 2034477-68-2C11H13N3OS
N-(2-(3-(Thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)pivalamide chemical structure, C14H19N3OS, CAS 2034365-96-1
N-(2-(3-(Thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)pivalamide
CAS 2034365-96-1C14H19N3OS
Ethyl (2-(3-(thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)carbamate chemical structure, C12H15N3O2S, CAS 2034235-65-7
Ethyl (2-(3-(thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)carbamate
CAS 2034235-65-7C12H15N3O2S
2-(N-Methylmethanesulfonamido)-N-{2-[3-(thiophen-3-yl)-1H-pyrazol-1-yl]ethyl}acetamide chemical structure, C13H18N4O3S2, CAS 2034260-02-9
2-(N-Methylmethanesulfonamido)-N-{2-[3-(thiophen-3-yl)-1H-pyrazol-1-yl]ethyl}acetamide
CAS 2034260-02-9C13H18N4O3S2
1-Propyl-3-(2-(3-(thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)urea chemical structure, C13H18N4OS, CAS 2034366-95-3
1-Propyl-3-(2-(3-(thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)urea
CAS 2034366-95-3C13H18N4OS
N-(2-(3-(Thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)methanesulfonamide chemical structure, C10H13N3O2S2, CAS 2034452-85-0
N-(2-(3-(Thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)methanesulfonamide
CAS 2034452-85-0C10H13N3O2S2
N-(2-(3-(Thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)propane-1-sulfonamide chemical structure, C12H17N3O2S2, CAS 2034366-99-7
N-(2-(3-(Thiophen-3-yl)-1H-pyrazol-1-yl)ethyl)propane-1-sulfonamide
CAS 2034366-99-7C12H17N3O2S2
Dimethyl({2-[3-(thiophen-3-yl)-1H-pyrazol-1-yl]ethyl}sulfamoyl)amine chemical structure, C11H16N4O2S2, CAS 2034367-01-4
Dimethyl({2-[3-(thiophen-3-yl)-1H-pyrazol-1-yl]ethyl}sulfamoyl)amine
CAS 2034367-01-4C11H16N4O2S2