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Murcko scaffold

Ring system with 3 rings and 15 atoms

49 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
49
With full pages
4
Scaffold SMILES

c1ccc2nc(N3CCCC3)ccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2nc(N3CCCC3)ccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

4-Methyl-2-(1-pyrrolidinyl)quinoline chemical structure, C14H16N2, CAS 53541-66-5
4-Methyl-2-(1-pyrrolidinyl)quinoline
CAS 53541-66-5C14H16N2
6,8-Dimethyl-2-pyrrolidin-1-yl-quinoline-3-carbaldehyde chemical structure, C16H18N2O, CAS 436088-26-5
6,8-Dimethyl-2-pyrrolidin-1-yl-quinoline-3-carbaldehyde
CAS 436088-26-5C16H18N2O
8-Methyl-2-(1-pyrrolidinyl)-4-(trifluoromethyl)quinoline chemical structure, C15H15F3N2, CAS 338750-09-7
8-Methyl-2-(1-pyrrolidinyl)-4-(trifluoromethyl)quinoline
CAS 338750-09-7C15H15F3N2
1-[4-Methyl-2-(1-pyrrolidinyl)-3-quinolinyl]-1-ethanone chemical structure, C16H18N2O, CAS 478247-20-0
1-[4-Methyl-2-(1-pyrrolidinyl)-3-quinolinyl]-1-ethanone
CAS 478247-20-0C16H18N2O
4,8-Dimethyl-2-(1-pyrrolidinyl)quinoline chemical structure, C15H18N2, CAS 338415-81-9
4,8-Dimethyl-2-(1-pyrrolidinyl)quinoline
CAS 338415-81-9C15H18N2
4-Methyl-6-nitro-2-(pyrrolidin-1-yl)quinoline chemical structure, C14H15N3O2, CAS 705271-61-0
4-Methyl-6-nitro-2-(pyrrolidin-1-yl)quinoline
CAS 705271-61-0C14H15N3O2
1-(3-Formylquinolin-2-yl)pyrrolidine-2-carboxamide chemical structure, C15H15N3O2, CAS 1009229-01-9
1-(3-Formylquinolin-2-yl)pyrrolidine-2-carboxamide
CAS 1009229-01-9C15H15N3O2
2-(Pyrrolidin-1-yl)quinolin-8-ol chemical structure, C13H14N2O, CAS 941868-37-7
2-(Pyrrolidin-1-yl)quinolin-8-ol
CAS 941868-37-7C13H14N2O
2-(Pyrrolidin-1-yl)quinoline-3-carboxylic acid chemical structure, C14H14N2O2, CAS 1017199-72-2
2-(Pyrrolidin-1-yl)quinoline-3-carboxylic acid
CAS 1017199-72-2C14H14N2O2
2-(1-Pyrrolidinyl)-3-quinolinecarboxaldehyde chemical structure, C14H14N2O, CAS 938138-99-9
2-(1-Pyrrolidinyl)-3-quinolinecarboxaldehyde
CAS 938138-99-9C14H14N2O
Carbamic acid, [1-(6-nitro-2-quinolinyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl ester chemical structure, C18H22N4O4, CAS 539855-71-5
Carbamic acid, [1-(6-nitro-2-quinolinyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl ester
CAS 539855-71-5C18H22N4O4
6-Bromo-2-(pyrrolidin-1-yl)quinoline chemical structure, C13H13BrN2, CAS 864866-59-1
6-Bromo-2-(pyrrolidin-1-yl)quinoline
CAS 864866-59-1C13H13BrN2
4-[(4-Methyl-2-pyrrolidin-1-ylquinolin-6-yl)amino]-4-oxobutanoic acid chemical structure, C18H21N3O3, CAS 1119451-16-9
4-[(4-Methyl-2-pyrrolidin-1-ylquinolin-6-yl)amino]-4-oxobutanoic acid
CAS 1119451-16-9C18H21N3O3
2-(Pyrrolidin-1-yl)quinoline-4-carboxylic acid chemical structure, C14H14N2O2, CAS 933754-81-5
2-(Pyrrolidin-1-yl)quinoline-4-carboxylic acid
CAS 933754-81-5C14H14N2O2
2-(Pyrrolidin-1-yl)quinoline-3-carboxylic acid hydrochloride chemical structure, C14H15ClN2O2, CAS 1240528-11-3
2-(Pyrrolidin-1-yl)quinoline-3-carboxylic acid hydrochloride
CAS 1240528-11-3C14H15ClN2O2
8-Chloro-2-pyrrolidin-1-ylquinoline-4-carboxylic acid chemical structure, C14H13ClN2O2, CAS 1242898-92-5
8-Chloro-2-pyrrolidin-1-ylquinoline-4-carboxylic acid
CAS 1242898-92-5C14H13ClN2O2
4-Methyl-2-pyrrolidin-1-ylquinolin-6-amine chemical structure, C14H17N3, CAS 1283398-68-4
4-Methyl-2-pyrrolidin-1-ylquinolin-6-amine
CAS 1283398-68-4C14H17N3
1-Quinolin-2-ylpyrrolidine-3-carboxylic acid chemical structure, C14H14N2O2, CAS 1271597-81-9
1-Quinolin-2-ylpyrrolidine-3-carboxylic acid
CAS 1271597-81-9C14H14N2O2
1-(4-Cyanoquinolin-2-yl)pyrrolidine-2-carboxamide chemical structure, C15H14N4O, CAS 1404902-71-1
1-(4-Cyanoquinolin-2-yl)pyrrolidine-2-carboxamide
CAS 1404902-71-1C15H14N4O
2-(Pyrrolidin-1-yl)quinoline-6-carboxylic acid chemical structure, C14H14N2O2, CAS 958332-92-8
2-(Pyrrolidin-1-yl)quinoline-6-carboxylic acid
CAS 958332-92-8C14H14N2O2
Ethyl 2-(1-pyrrolidinyl)-6-quinolinecarboxylate chemical structure, C16H18N2O2, CAS 958332-88-2
Ethyl 2-(1-pyrrolidinyl)-6-quinolinecarboxylate
CAS 958332-88-2C16H18N2O2
4-Chloro-7-methoxy-2-(pyrrolidin-1-yl)quinoline chemical structure, C14H15ClN2O, CAS 1409965-67-8
4-Chloro-7-methoxy-2-(pyrrolidin-1-yl)quinoline
CAS 1409965-67-8C14H15ClN2O
[(2S)-1-(6-Nitroquinolin-2-yl)pyrrolidin-2-yl]methanol chemical structure, C14H15N3O3, CAS 138219-89-3
[(2S)-1-(6-Nitroquinolin-2-yl)pyrrolidin-2-yl]methanol
CAS 138219-89-3C14H15N3O3
3-Pyrrolidinepropanoic acid, 1-(3-methyl-2-quinolinyl)- chemical structure, C17H20N2O2, CAS 1509381-39-8
3-Pyrrolidinepropanoic acid, 1-(3-methyl-2-quinolinyl)-
CAS 1509381-39-8C17H20N2O2