CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
24
With full pages
5
Scaffold SMILES

c1ccc(CNc2ccc3ncncc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNc2ccc3ncncc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

Pam 1392 chemical structure, C15H13Cl2N5, CAS 13794-65-5
Pam 1392
CAS 13794-65-5C15H13Cl2N5
5-Chloro-5,8-dideazaisoaminopterin chemical structure, C21H21ClN6O5, CAS 97541-74-7
5-Chloro-5,8-dideazaisoaminopterin
CAS 97541-74-7C21H21ClN6O5
AM 2159 chemical structure, C16H16ClN5, CAS 83654-06-2
AM 2159
CAS 83654-06-2C16H16ClN5
Nitroquine chemical structure, C15H12Cl2N6O, CAS 22316-71-8
Nitroquine
CAS 22316-71-8C15H12Cl2N6O
Quinazoline, 2,4-diamino-6-((3,4-dichlorobenzyl)methylamino)-, hydrochloride, hemihydrate chemical structure, C16H16Cl3N5, CAS 40066-23-7
Quinazoline, 2,4-diamino-6-((3,4-dichlorobenzyl)methylamino)-, hydrochloride, hemihydrate
CAS 40066-23-7C16H16Cl3N5
N6-[(3,4-Dichlorophenyl)methyl]-N6-methyl-2,4,6-quinazolinetriamine chemical structure, C16H15Cl2N5, CAS 40066-22-6
N6-[(3,4-Dichlorophenyl)methyl]-N6-methyl-2,4,6-quinazolinetriamine
CAS 40066-22-6C16H15Cl2N5
Quinazoline, 6-(benzylmethylamino)-2,4-diamino-, hydrochloride, hydrate chemical structure, C16H18ClN5, CAS 40066-25-9
Quinazoline, 6-(benzylmethylamino)-2,4-diamino-, hydrochloride, hydrate
CAS 40066-25-9C16H18ClN5
2,6-Quinazolinetriamine, N(6)-[(4-bromophenyl)methyl]- chemical structure, C15H14BrN5, CAS 13794-62-2
2,6-Quinazolinetriamine, N(6)-[(4-bromophenyl)methyl]-
CAS 13794-62-2C15H14BrN5
n6-(2-Chlorobenzyl)quinazoline-2,4,6-triamine chemical structure, C15H14ClN5, CAS 13953-73-6
n6-(2-Chlorobenzyl)quinazoline-2,4,6-triamine
CAS 13953-73-6C15H14ClN5
N6-[(3,4,5-trimethoxyphenyl)methyl]quinazoline-2,4,6-triamine chemical structure, C18H21N5O3, CAS 13794-67-7
N6-[(3,4,5-trimethoxyphenyl)methyl]quinazoline-2,4,6-triamine
CAS 13794-67-7C18H21N5O3
6-N-[(4-Fluorophenyl)methyl]quinazoline-2,4,6-triamine chemical structure, C15H14FN5, CAS 13794-63-3
6-N-[(4-Fluorophenyl)methyl]quinazoline-2,4,6-triamine
CAS 13794-63-3C15H14FN5
6-N-[(3,4-Dichlorophenyl)methyl]-6-N-ethyl-5-methylquinazoline-2,4,6-triamine chemical structure, C18H19Cl2N5, CAS 40066-33-9
6-N-[(3,4-Dichlorophenyl)methyl]-6-N-ethyl-5-methylquinazoline-2,4,6-triamine
CAS 40066-33-9C18H19Cl2N5
N~6~-[(3,4-Dichlorophenyl)methyl]-N~6~-propylquinazoline-2,4,6-triamine chemical structure, C18H19Cl2N5, CAS 36847-09-3
N~6~-[(3,4-Dichlorophenyl)methyl]-N~6~-propylquinazoline-2,4,6-triamine
CAS 36847-09-3C18H19Cl2N5
2-[[4-[[(2,4-Diamino-5-methylquinazolin-6-yl)amino]methyl]benzoyl]amino]pentanedioic acid chemical structure, C22H24N6O5, CAS 56277-34-0
2-[[4-[[(2,4-Diamino-5-methylquinazolin-6-yl)amino]methyl]benzoyl]amino]pentanedioic acid
CAS 56277-34-0C22H24N6O5
(S)-2-(4-(((2,4-Diaminoquinazolin-6-yl)amino)methyl)benzamido)pentanedioic acid chemical structure, C21H22N6O5, CAS 56239-22-6
(S)-2-(4-(((2,4-Diaminoquinazolin-6-yl)amino)methyl)benzamido)pentanedioic acid
CAS 56239-22-6C21H22N6O5
Diethyl 2-[[4-[[(2,4-diaminoquinazolin-6-yl)amino]methyl]benzoyl]amino]pentanedioate chemical structure, C25H30N6O5, CAS 56239-20-4
Diethyl 2-[[4-[[(2,4-diaminoquinazolin-6-yl)amino]methyl]benzoyl]amino]pentanedioate
CAS 56239-20-4C25H30N6O5
2,4-Diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline chemical structure, C18H21N5O2, CAS 213338-96-6
2,4-Diamino-6-[N-(2',5'-dimethoxybenzyl)-N-methylamino]quinazoline
CAS 213338-96-6C18H21N5O2
Benzonitrile, 4-(((2-amino-4-(methylamino)-6-quinazolinyl)methylamino)methyl)- chemical structure, C18H18N6, CAS 150893-08-6
Benzonitrile, 4-(((2-amino-4-(methylamino)-6-quinazolinyl)methylamino)methyl)-
CAS 150893-08-6C18H18N6
N6-Methyl-N6-(3,4,5-trimethoxybenzyl)quinazoline-2,4,6-triamine chemical structure, C19H23N5O3, CAS 714907-26-3
N6-Methyl-N6-(3,4,5-trimethoxybenzyl)quinazoline-2,4,6-triamine
CAS 714907-26-3C19H23N5O3
6-(1-Benzylhydrazinyl)quinazoline-2,4-diamine chemical structure, C15H16N6, CAS 89176-64-7
6-(1-Benzylhydrazinyl)quinazoline-2,4-diamine
CAS 89176-64-7C15H16N6
Acetic acid--6-(1-benzylhydrazinyl)quinazoline-2,4-diamine (1/1) chemical structure, C17H20N6O2, CAS 89176-65-8
Acetic acid--6-(1-benzylhydrazinyl)quinazoline-2,4-diamine (1/1)
CAS 89176-65-8C17H20N6O2
6-{1-[(3,4-Dichlorophenyl)methyl]hydrazinyl}quinazoline-2,4-diamine chemical structure, C15H14Cl2N6, CAS 89176-70-5
6-{1-[(3,4-Dichlorophenyl)methyl]hydrazinyl}quinazoline-2,4-diamine
CAS 89176-70-5C15H14Cl2N6
N6-[(2-Bromophenyl)methyl]-2,4,6-quinazolinetriamine chemical structure, C15H14BrN5, CAS 118291-96-6
N6-[(2-Bromophenyl)methyl]-2,4,6-quinazolinetriamine
CAS 118291-96-6C15H14BrN5
N6-Methyl-N6-(3,4,5-trimethoxybenzyl)quinazoline-2,4,6-triamine hydrochloride chemical structure, C19H24ClN5O3, CAS 122246-50-8
N6-Methyl-N6-(3,4,5-trimethoxybenzyl)quinazoline-2,4,6-triamine hydrochloride
CAS 122246-50-8C19H24ClN5O3