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Murcko scaffold

Ring system with 3 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
9
With full pages
3
Scaffold SMILES

O=C1CC(c2ccccc2)CC(c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(c2ccccc2)CC(c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

3,5-Bis[4-(dimethylamino)phenyl]-4-heptanoyl-2-pentylcyclohexan-1-one chemical structure, C34H50N2O2, CAS 54951-60-9
3,5-Bis[4-(dimethylamino)phenyl]-4-heptanoyl-2-pentylcyclohexan-1-one
CAS 54951-60-9C34H50N2O2
4-(3-Methylbutanoyl)-3,5-diphenyl-2-propan-2-ylcyclohexan-1-one chemical structure, C26H32O2, CAS 18346-83-3
4-(3-Methylbutanoyl)-3,5-diphenyl-2-propan-2-ylcyclohexan-1-one
CAS 18346-83-3C26H32O2
Ethyl 4-hydroxy-2-oxo-4,6-diphenylcyclohexanecarboxylate chemical structure, C21H22O4, CAS 85156-98-5
Ethyl 4-hydroxy-2-oxo-4,6-diphenylcyclohexanecarboxylate
CAS 85156-98-5C21H22O4
3-Cyano-4-hydroxy-6-oxo-2,4-diphenyl-cyclohexanecarboxylic acid ethyl ester chemical structure, C22H21NO4, CAS 90699-77-7
3-Cyano-4-hydroxy-6-oxo-2,4-diphenyl-cyclohexanecarboxylic acid ethyl ester
CAS 90699-77-7C22H21NO4
2-(4-CL-PH)-3-Cyano-4-HO-6-oxo-4-phenyl-cyclohexanecarboxylic acid ethyl ester chemical structure, C22H20ClNO4, CAS 104503-26-6
2-(4-CL-PH)-3-Cyano-4-HO-6-oxo-4-phenyl-cyclohexanecarboxylic acid ethyl ester
CAS 104503-26-6C22H20ClNO4
Dimethyl 4-oxo-2,6-diphenylcyclohexane-1,1-dicarboxylate chemical structure, C22H22O5, CAS 41167-36-6
Dimethyl 4-oxo-2,6-diphenylcyclohexane-1,1-dicarboxylate
CAS 41167-36-6C22H22O5
Cyclohexanone, 3,5-bis(4-chlorophenyl)- chemical structure, C18H16Cl2O, CAS 26379-98-6
Cyclohexanone, 3,5-bis(4-chlorophenyl)-
CAS 26379-98-6C18H16Cl2O
cis-(3S,5R)-3-(4-Hydroxyphenyl)-5-phenylcyclohexan-1-one chemical structure, C18H18O2, CAS 88362-82-7
cis-(3S,5R)-3-(4-Hydroxyphenyl)-5-phenylcyclohexan-1-one
CAS 88362-82-7C18H18O2
cis-(3S,5R)-3-(4-Methoxyphenyl)-5-phenylcyclohexan-1-one chemical structure, C19H20O2, CAS 88362-81-6
cis-(3S,5R)-3-(4-Methoxyphenyl)-5-phenylcyclohexan-1-one
CAS 88362-81-6C19H20O2