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Murcko scaffold

1,3-Dioxane scaffold

1,001 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
1,001
With full pages
85
Scaffold SMILES

C1COCOC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,3-Dioxane page
Murcko scaffold C1COCOC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,001 chemicals

5-Bromo-5-nitro-1,3-dioxane chemical structure, C4H6BrNO4, CAS 30007-47-7
5-Bromo-5-nitro-1,3-dioxane
CAS 30007-47-7C4H6BrNO4
1,3-Dioxane chemical structure, C4H8O2, CAS 505-22-6
1,3-Dioxane
CAS 505-22-6C4H8O2
4,4-Dimethyl-1,3-dioxane chemical structure, C6H12O2, CAS 766-15-4
4,4-Dimethyl-1,3-dioxane
CAS 766-15-4C6H12O2
1,3-Dioxane, 2,4-dimethyl- chemical structure, C6H12O2, CAS 766-20-1
1,3-Dioxane, 2,4-dimethyl-
CAS 766-20-1C6H12O2
Dimethoxane chemical structure, C8H14O4, CAS 828-00-2
Dimethoxane
CAS 828-00-2C8H14O4
4-Methyl-1,3-dioxane chemical structure, C5H10O2, CAS 1120-97-4
4-Methyl-1,3-dioxane
CAS 1120-97-4C5H10O2
5-Methyl-1,3-dioxane-5-methanol chemical structure, C6H12O3, CAS 1121-97-7
5-Methyl-1,3-dioxane-5-methanol
CAS 1121-97-7C6H12O3
5-Methyl-5-nitro-1,3-dioxane chemical structure, C5H9NO4, CAS 1194-36-1
5-Methyl-5-nitro-1,3-dioxane
CAS 1194-36-1C5H9NO4
1,3-Dioxane, 5,5-diethyl- chemical structure, C8H16O2, CAS 3390-07-6
1,3-Dioxane, 5,5-diethyl-
CAS 3390-07-6C8H16O2
5-Ethyl-5-nitro-2-propyl-1,3-dioxane chemical structure, C9H17NO4, CAS 5702-40-9
5-Ethyl-5-nitro-2-propyl-1,3-dioxane
CAS 5702-40-9C9H17NO4
2-Hexyl-2,4-dimethyl-1,3-dioxane chemical structure, C12H24O2, CAS 6290-07-9
2-Hexyl-2,4-dimethyl-1,3-dioxane
CAS 6290-07-9C12H24O2
5-Ethyl-5-(1-methoxyethyl)-2-(propan-2-yl)-1,3-dioxane chemical structure, C12H24O3, CAS 17388-06-6
5-Ethyl-5-(1-methoxyethyl)-2-(propan-2-yl)-1,3-dioxane
CAS 17388-06-6C12H24O3
5-Ethyl-5-(2-methoxyethyl)-2-propan-2-yl-1,3-dioxane chemical structure, C12H24O3, CAS 22644-59-3
5-Ethyl-5-(2-methoxyethyl)-2-propan-2-yl-1,3-dioxane
CAS 22644-59-3C12H24O3
2,5-Dimethyl-5-(1-((propan-2-yl)oxy)ethyl)-1,3-dioxane chemical structure, C11H22O3, CAS 19131-74-9
2,5-Dimethyl-5-(1-((propan-2-yl)oxy)ethyl)-1,3-dioxane
CAS 19131-74-9C11H22O3
2-(Propan-2-yl)-5-propyl-1,3-dioxane chemical structure, C10H20O2, CAS 19476-83-6
2-(Propan-2-yl)-5-propyl-1,3-dioxane
CAS 19476-83-6C10H20O2
2-Methyl-5-(1-((propan-2-yl)oxy)ethyl)-5-propyl-1,3-dioxane chemical structure, C13H26O3, CAS 19476-85-8
2-Methyl-5-(1-((propan-2-yl)oxy)ethyl)-5-propyl-1,3-dioxane
CAS 19476-85-8C13H26O3
5-(Methoxymethyl)-2,5-dimethyl-1,3-dioxane chemical structure, C8H16O3, CAS 19476-87-0
5-(Methoxymethyl)-2,5-dimethyl-1,3-dioxane
CAS 19476-87-0C8H16O3
4,4,6-Trimethyl-2-vinyl-1,3-dioxane chemical structure, C9H16O2, CAS 22634-89-5
4,4,6-Trimethyl-2-vinyl-1,3-dioxane
CAS 22634-89-5C9H16O2
5-(Methoxymethyl)-2,5-di(propan-2-yl)-1,3-dioxane chemical structure, C12H24O3, CAS 101198-15-6
5-(Methoxymethyl)-2,5-di(propan-2-yl)-1,3-dioxane
CAS 101198-15-6C12H24O3
m-Dioxane, 5-(isopropoxymethyl)-2-isopropyl-5-methyl-, (E)- chemical structure, C12H24O3, CAS 22644-54-8
m-Dioxane, 5-(isopropoxymethyl)-2-isopropyl-5-methyl-, (E)-
CAS 22644-54-8C12H24O3
5-Ethyl-5-(1-methoxyethyl)-2-methyl-1,3-dioxane chemical structure, C10H20O3, CAS 22644-56-0
5-Ethyl-5-(1-methoxyethyl)-2-methyl-1,3-dioxane
CAS 22644-56-0C10H20O3
cis-5-Allyl-5-(1-methoxyethyl)-2-methyl-1,3-dioxane chemical structure, C11H20O3, CAS 22644-65-1
cis-5-Allyl-5-(1-methoxyethyl)-2-methyl-1,3-dioxane
CAS 22644-65-1C11H20O3
cis-5-Allyl-2-methyl-5-(1-propoxyethyl)-1,3-dioxane chemical structure, C13H24O3, CAS 22644-69-5
cis-5-Allyl-2-methyl-5-(1-propoxyethyl)-1,3-dioxane
CAS 22644-69-5C13H24O3
2-(Propan-2-yl)-5-(prop-2-en-1-yl)-5-(1-propoxyethyl)-1,3-dioxane chemical structure, C15H28O3, CAS 22644-70-8
2-(Propan-2-yl)-5-(prop-2-en-1-yl)-5-(1-propoxyethyl)-1,3-dioxane
CAS 22644-70-8C15H28O3