CompoundList
Sign in
Heterocyclic building blocks

1,3-Dioxane

Also known as m-Dioxane, 1,3-Dioxacyclohexane, 1,3-Propanediol formal

CAS 505-22-6Formula C4H8O2Molar mass 88.11 g/molEC 208-005-1
GHS signal word: Danger. Pictograms: Flammable, Harmful or irritant 3 suppliers listed
Get quotes Compare 3 suppliers
1,3-Dioxane chemical structure, C4H8O2, CAS 505-22-6
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Liquid
Melting point
-42 °C
Boiling point
105 °C
Density
1.0342 AT 20 °C/4 °C
Flash point
2 °C
HS code
293299
Category
Heterocyclic building blocks
UN number
UN 1165
Illustrative photo, closed blue jerry cans in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is 1,3-Dioxane?

Plain description, key identifiers and synonyms

1,3-dioxane is a dioxane and a cyclic acetal.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,3-dioxane
CAS number
505-22-6 CAS number cross-checked
EC number
208-005-1
Molecular formula
C4H8O2
UNII
B2C8M17I09
MDL number
MFCD00006566
InChIKey
VDFVNEFVBPFDSB-UHFFFAOYSA-N
InChI
InChI=1S/C4H8O2/c1-2-5-4-6-3-1/h1-4H2
SMILES (canonical and isomeric)
C1COCOC1

Synonyms

  • m-Dioxane
  • 1,3-Dioxacyclohexane
  • 1,3-Propanediol formal
  • meta-Dioxane
  • m-Dioxin, dihydro-
  • Trimethylene glycol methylene ether
  • dihydro-m-dioxin
  • 2,4-dioxane
  • 1-5-dioxane
  • 2,6-dioxane
  • 1,3-dioxan
  • B-1,3-dioxane
  • 1,3-Dioxane, 97%
  • 1,3-Dioxane Solution in Methanol, 1000ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Liquidexp.
Melting point
-42 °Cexp.
Boiling point
105 °Cexp.
Density
1.0342 AT 20 °C/4 °Cexp.
Flash point
2 °Cexp.
Solubility
SOL IN WATER, ALC, ETHANOL, ACETONE, BENZENEexp.
Vapour pressure
39 mm Hg at 25 °C (estimated)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
88.11 g/molcalc.
Exact mass
88.0524 Dacalc.
LogP (octanol/water)
0.38calc.
Topological polar surface area
18.46 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
6calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1COCOC1

C1COCOC1

1 ring, 6 atoms. This chemical is the scaffold itself.

1,000 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H225Highly flammable liquid and vapour.
  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H332Harmful if inhaled.
Precautionary statements (23)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 1165

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

1,3-Dioxane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 3 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

3 suppliers in 1 country

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

1,3-Dioxane price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Monomer for acetyl resins (no evidence of current use).

How it is made

Reaction of 1,3-propylene glycol and formaldehyde

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 1,3-Dioxane is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 1,3-Dioxane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 1,3-Dioxane, based on the data on this page

What is 1,3-Dioxane?

1,3-dioxane is a dioxane and a cyclic acetal.

What is the CAS number of 1,3-Dioxane?

The CAS registry number of 1,3-Dioxane is 505-22-6.

What is the molecular formula and weight of 1,3-Dioxane?

The molecular formula of 1,3-Dioxane is C4H8O2 and its molar mass is 88.11 g/mol.

What is 1,3-Dioxane used for?

Monomer for acetyl resins (no evidence of current use).

Is 1,3-Dioxane hazardous?

1,3-Dioxane carries the GHS signal word "Danger". Main hazards: highly flammable liquid and vapour, harmful if swallowed, harmful in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 1,3-Dioxane?

1,3-Dioxane is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 1,3-Dioxane?

CompoundList lists 3 suppliers of 1,3-Dioxane in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 1,3-Dioxane?

Suppliers quote 1,3-Dioxane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 1,3-Dioxane

Get quotes for 1,3-Dioxane

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell 1,3-Dioxane
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of 1,3-Dioxane with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/1-3-dioxane-505-22-6" title="1,3-Dioxane structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Heterocyclic building blocks or HS code 293299

3 suppliers
Free quotes, contact stays private
Get quotes