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Murcko scaffold

Ring system with 3 rings and 17 atoms

24 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 24
With full pages: 3

Scaffold SMILES

O=C(Nc1nncs1)c1cc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1nncs1)c1cc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

3-Chloro-6-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C13H10ClN3OS2, CAS 5689-55-4

3-Chloro-6-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 5689-55-4C₁₃H₁₀ClN₃OS₂

3-Chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C13H10ClN3OS2, CAS 331736-82-4

3-Chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 331736-82-4C₁₃H₁₀ClN₃OS₂

3-Chloro-6-methyl-N-(1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C12H8ClN3OS2, CAS 424817-12-9

3-Chloro-6-methyl-N-(1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 424817-12-9C₁₂H₈ClN₃OS₂

3-Chloro-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C13H10ClN3O2S2, CAS 600122-44-9

3-Chloro-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 600122-44-9C₁₃H₁₀ClN₃O₂S₂

3-Chloro-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C14H12ClN3OS2, CAS 600122-40-5

3-Chloro-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 600122-40-5C₁₄H₁₂ClN₃OS₂

3-Chloro-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C14H12ClN3OS2, CAS 620577-63-1

3-Chloro-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 620577-63-1C₁₄H₁₂ClN₃OS₂

N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-3-chloro-1-benzothiophene-2-carboxamide chemical structure, C15H14ClN3OS2, CAS 600122-34-7

N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-3-chloro-1-benzothiophene-2-carboxamide

CAS 600122-34-7C₁₅H₁₄ClN₃OS₂

3-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C13H10ClN3OS3, CAS 314022-95-2

3-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 314022-95-2C₁₃H₁₀ClN₃OS₃

3-Chloro-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C15H14ClN3OS2, CAS 600122-39-2

3-Chloro-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 600122-39-2C₁₅H₁₄ClN₃OS₂

3-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-6-methyl-1-benzothiophene-2-carboxamide chemical structure, C14H12ClN3OS3, CAS 540529-34-8

3-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-6-methyl-1-benzothiophene-2-carboxamide

CAS 540529-34-8C₁₄H₁₂ClN₃OS₃

3-Chloro-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)-4-fluoro-1-benzothiophene-2-carboxamide chemical structure, C13H9ClFN3OS3, CAS 774575-10-9

3-Chloro-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)-4-fluoro-1-benzothiophene-2-carboxamide

CAS 774575-10-9C₁₃H₉ClFN₃OS₃

3-Chloro-N-[5-(pentan-3-yl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C16H16ClN3OS2, CAS 600640-93-5

3-Chloro-N-[5-(pentan-3-yl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 600640-93-5C₁₆H₁₆ClN₃OS₂

N-(5-Butyl-1,3,4-thiadiazol-2-yl)-3-chloro-1-benzothiophene-2-carboxamide chemical structure, C15H14ClN3OS2, CAS 692764-42-4

N-(5-Butyl-1,3,4-thiadiazol-2-yl)-3-chloro-1-benzothiophene-2-carboxamide

CAS 692764-42-4C₁₅H₁₄ClN₃OS₂

3-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-6-fluoro-1-benzothiophene-2-carboxamide chemical structure, C13H9ClFN3OS3, CAS 571925-67-2

3-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-6-fluoro-1-benzothiophene-2-carboxamide

CAS 571925-67-2C₁₃H₉ClFN₃OS₃

3-Chloro-N-(5-pentyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C16H16ClN3OS2, CAS 708237-26-7

3-Chloro-N-(5-pentyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 708237-26-7C₁₆H₁₆ClN₃OS₂

3-Chloro-N-[5-(2-ethoxyethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C15H14ClN3O2S2, CAS 717878-07-4

3-Chloro-N-[5-(2-ethoxyethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 717878-07-4C₁₅H₁₄ClN₃O₂S₂

3-Chloro-N-[5-(pentan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C16H16ClN3OS2, CAS 710980-77-1

3-Chloro-N-[5-(pentan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 710980-77-1C₁₆H₁₆ClN₃OS₂

3-Chloro-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C12H5ClF3N3OS2, CAS 600122-35-8

3-Chloro-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 600122-35-8C₁₂H₅ClF₃N₃OS₂

3,4,6-Trichloro-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C12H6Cl3N3OS2, CAS 879864-11-6

3,4,6-Trichloro-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 879864-11-6C₁₂H₆Cl₃N₃OS₂

3-Chloro-N-[5-(2,2-dimethylpropyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C16H16ClN3OS2, CAS 600122-45-0

3-Chloro-N-[5-(2,2-dimethylpropyl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 600122-45-0C₁₆H₁₆ClN₃OS₂

3-Chloro-4-fluoro-N-(1,3,4-thiadiazol-2-yl)benzo[b]thiophene-2-carboxamide chemical structure, C11H5ClFN3OS2, CAS 588674-12-8

3-Chloro-4-fluoro-N-(1,3,4-thiadiazol-2-yl)benzo[b]thiophene-2-carboxamide

CAS 588674-12-8C₁₁H₅ClFN₃OS₂

3-Chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-6-fluoro-1-benzothiophene-2-carboxamide chemical structure, C13H9ClFN3OS2, CAS 561005-80-9

3-Chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-6-fluoro-1-benzothiophene-2-carboxamide

CAS 561005-80-9C₁₃H₉ClFN₃OS₂

3-Chloro-6-fluoro-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide chemical structure, C14H11ClFN3OS2, CAS 905784-44-3

3-Chloro-6-fluoro-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzothiophene-2-carboxamide

CAS 905784-44-3C₁₄H₁₁ClFN₃OS₂

3-Chloro-6-fluoro-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide chemical structure, C14H11ClFN3OS2, CAS 905768-85-6

3-Chloro-6-fluoro-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzothiophene-2-carboxamide

CAS 905768-85-6C₁₄H₁₁ClFN₃OS₂