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Murcko scaffold

Ring system with 3 rings and 17 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
27
With full pages
9
Scaffold SMILES

O=C(Nc1nncs1)c1cc2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nncs1)c1cc2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

N-(5-Methyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C12H9N3O2S, CAS 330557-46-5
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 330557-46-5C12H9N3O2S
N-(5-Propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H13N3O2S, CAS 691385-88-3
N-(5-Propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 691385-88-3C14H13N3O2S
N-[5-(Pentan-3-yl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide chemical structure, C16H17N3O2S, CAS 692743-64-9
N-[5-(Pentan-3-yl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide
CAS 692743-64-9C16H17N3O2S
3,5-Dimethyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H13N3O2S, CAS 620586-15-4
3,5-Dimethyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 620586-15-4C14H13N3O2S
3,5-Dimethyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C16H17N3O2S, CAS 620586-21-2
3,5-Dimethyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 620586-21-2C16H17N3O2S
3,5,6-Trimethyl-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide chemical structure, C17H19N3O2S, CAS 622349-91-1
3,5,6-Trimethyl-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide
CAS 622349-91-1C17H19N3O2S
3,5,6-Trimethyl-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide chemical structure, C18H21N3O2S, CAS 622349-92-2
3,5,6-Trimethyl-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide
CAS 622349-92-2C18H21N3O2S
5-Chloro-3-methyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C15H14ClN3O2S, CAS 714261-80-0
5-Chloro-3-methyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 714261-80-0C15H14ClN3O2S
5-Chloro-3-methyl-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide chemical structure, C13H10ClN3O2S2, CAS 714261-92-4
5-Chloro-3-methyl-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide
CAS 714261-92-4C13H10ClN3O2S2
5-Ethyl-3-methyl-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide chemical structure, C15H15N3O2S2, CAS 714262-05-2
5-Ethyl-3-methyl-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide
CAS 714262-05-2C15H15N3O2S2
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C15H15N3O2S, CAS 691867-86-4
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 691867-86-4C15H15N3O2S
5-Bromo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide chemical structure, C14H12BrN3O2S, CAS 762251-18-3
5-Bromo-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide
CAS 762251-18-3C14H12BrN3O2S
5-Bromo-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C14H12BrN3O2S2, CAS 785705-21-7
5-Bromo-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-3-methyl-1-benzofuran-2-carboxamide
CAS 785705-21-7C14H12BrN3O2S2
3,6-Dimethyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H13N3O2S, CAS 823827-56-1
3,6-Dimethyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 823827-56-1C14H13N3O2S
5-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C14H12ClN3O2S2, CAS 825655-87-6
5-Chloro-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-3-methyl-1-benzofuran-2-carboxamide
CAS 825655-87-6C14H12ClN3O2S2
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-(propan-2-yloxymethyl)-1-benzofuran-2-carboxamide chemical structure, C17H19N3O3S, CAS 790679-69-5
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-(propan-2-yloxymethyl)-1-benzofuran-2-carboxamide
CAS 790679-69-5C17H19N3O3S
N-[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-5-fluoro-3-methyl-1-benzofuran-2-carboxamide chemical structure, C14H12FN3O2S2, CAS 825659-31-2
N-[5-(Ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-5-fluoro-3-methyl-1-benzofuran-2-carboxamide
CAS 825659-31-2C14H12FN3O2S2
5-Ethyl-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-3-methyl-1-benzofuran-2-carboxamide chemical structure, C16H17N3O2S2, CAS 826998-16-7
5-Ethyl-N-[5-(ethylsulfanyl)-1,3,4-thiadiazol-2-yl]-3-methyl-1-benzofuran-2-carboxamide
CAS 826998-16-7C16H17N3O2S2
3,5-Dimethyl-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide chemical structure, C16H17N3O2S, CAS 620586-24-5
3,5-Dimethyl-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]-1-benzofuran-2-carboxamide
CAS 620586-24-5C16H17N3O2S
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3,5,6-trimethyl-1-benzofuran-2-carboxamide chemical structure, C16H17N3O2S, CAS 622349-89-7
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3,5,6-trimethyl-1-benzofuran-2-carboxamide
CAS 622349-89-7C16H17N3O2S
3,5,6-Trimethyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C17H19N3O2S, CAS 622349-90-0
3,5,6-Trimethyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 622349-90-0C17H19N3O2S
3-Methyl-N-(1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C12H9N3O2S, CAS 588674-67-3
3-Methyl-N-(1,3,4-thiadiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 588674-67-3C12H9N3O2S
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide chemical structure, C14H13N3O2S, CAS 887709-39-9
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide
CAS 887709-39-9C14H13N3O2S
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide chemical structure, C16H17N3O2S, CAS 1002459-05-3
N-(5-Butyl-1,3,4-thiadiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide
CAS 1002459-05-3C16H17N3O2S