CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

50 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
50
With full pages
14
Scaffold SMILES

O=C(Nc1cc2c(s1)CCCC2)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cc2c(s1)CCCC2)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 50 chemicals

Ethyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C16H17NO3S2, CAS 184906-67-0
Ethyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 184906-67-0C16H17NO3S2
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)thiophene-2-carboxamide chemical structure, C14H12N2OS2, CAS 313662-16-7
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)thiophene-2-carboxamide
CAS 313662-16-7C14H12N2OS2
N-(6-tert-Butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)thiophene-2-carboxamide chemical structure, C18H20N2OS2, CAS 303135-81-1
N-(6-tert-Butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)thiophene-2-carboxamide
CAS 303135-81-1C18H20N2OS2
Methyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C15H15NO3S2, CAS 301319-85-7
Methyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 301319-85-7C15H15NO3S2
2-(Thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C14H14N2O2S2, CAS 312925-55-6
2-(Thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 312925-55-6C14H14N2O2S2
N-Methyl-2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C15H16N2O2S2, CAS 324543-44-4
N-Methyl-2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 324543-44-4C15H16N2O2S2
2-(Thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid chemical structure, C14H13NO3S2, CAS 315679-50-6
2-(Thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid
CAS 315679-50-6C14H13NO3S2
N-(Propan-2-yl)-2-[(thiophen-2-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H20N2O2S2, CAS 5794-55-8
N-(Propan-2-yl)-2-[(thiophen-2-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 5794-55-8C17H20N2O2S2
N-Ethyl-2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H18N2O2S2, CAS 503843-51-4
N-Ethyl-2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 503843-51-4C16H18N2O2S2
2-[[Oxo(thiophen-2-yl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl ester chemical structure, C17H19NO3S2, CAS 329221-65-0
2-[[Oxo(thiophen-2-yl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl ester
CAS 329221-65-0C17H19NO3S2
Ethyl 2-(5-chlorothiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate chemical structure, C16H16ClNO3S2, CAS 350999-99-4
Ethyl 2-(5-chlorothiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS 350999-99-4C16H16ClNO3S2
N,N-Dipropyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C20H26N2O2S2, CAS 331718-78-6
N,N-Dipropyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 331718-78-6C20H26N2O2S2
N,N-Diethyl-2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C18H22N2O2S2, CAS 301321-93-7
N,N-Diethyl-2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 301321-93-7C18H22N2O2S2
2-Methoxyethyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C17H19NO4S2, CAS 352691-32-8
2-Methoxyethyl 2-[(2-thienylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 352691-32-8C17H19NO4S2
2-Methoxyethyl 2-[(4,5-dibromothiophene-2-carbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C17H17Br2NO4S2, CAS 438214-17-6
2-Methoxyethyl 2-[(4,5-dibromothiophene-2-carbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 438214-17-6C17H17Br2NO4S2
N-(3-Methoxypropyl)-2-[(thiophen-2-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C18H22N2O3S2, CAS 434302-75-7
N-(3-Methoxypropyl)-2-[(thiophen-2-ylcarbonyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 434302-75-7C18H22N2O3S2
N-Prop-2-enyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C17H18N2O2S2, CAS 459180-80-4
N-Prop-2-enyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 459180-80-4C17H18N2O2S2
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-nitrothiophene-2-carboxamide chemical structure, C14H11N3O3S2, CAS 328038-41-1
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-nitrothiophene-2-carboxamide
CAS 328038-41-1C14H11N3O3S2
Ethyl 2-(5-nitrothiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate chemical structure, C16H16N2O5S2, CAS 328038-33-1
Ethyl 2-(5-nitrothiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS 328038-33-1C16H16N2O5S2
6-Methyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid chemical structure, C15H15NO3S2, CAS 315679-26-6
6-Methyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid
CAS 315679-26-6C15H15NO3S2
N-(3-Hydroxypropyl)-6-methyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C18H22N2O3S2, CAS 455898-18-7
N-(3-Hydroxypropyl)-6-methyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 455898-18-7C18H22N2O3S2
AG-690/36165006 chemical structure, C17H18ClNO3S2, CAS 5245-43-2
AG-690/36165006
CAS 5245-43-2C17H18ClNO3S2
Ethyl 6-methyl-2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate chemical structure, C17H19NO3S2, CAS 329067-74-5
Ethyl 6-methyl-2-(thiophene-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS 329067-74-5C17H19NO3S2
N,N-Diethyl-6-methyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide chemical structure, C19H24N2O2S2, CAS 5578-58-5
N,N-Diethyl-6-methyl-2-(thiophene-2-carbonylamino)-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide
CAS 5578-58-5C19H24N2O2S2