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Murcko scaffold

N-(1,3-Thiazol-2-yl)-1-benzofuran-2-carboxamide scaffold

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
24
With full pages
10
Scaffold SMILES

O=C(Nc1nccs1)c1cc2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Thiazol-2-yl)-1-benzofuran-2-carboxamide page
Murcko scaffold O=C(Nc1nccs1)c1cc2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

Methyl 4-methyl-2-{[(3-methyl-1-benzofuran-2-yl)carbonyl]amino}-1,3-thiazole-5-carboxylate chemical structure, C16H14N2O4S, CAS 383371-74-2
Methyl 4-methyl-2-{[(3-methyl-1-benzofuran-2-yl)carbonyl]amino}-1,3-thiazole-5-carboxylate
CAS 383371-74-2C16H14N2O4S
N-(1,3-Thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C12H8N2O2S, CAS 304889-34-7
N-(1,3-Thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 304889-34-7C12H8N2O2S
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C15H12N2O3S, CAS 325746-48-3
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 325746-48-3C15H12N2O3S
N-(4-Methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C13H10N2O2S, CAS 91822-76-3
N-(4-Methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 91822-76-3C13H10N2O2S
Ethyl 4-methyl-2-(3-methylbenzofuran-2-carboxamido)thiazole-5-carboxylate chemical structure, C17H16N2O4S, CAS 378764-56-8
Ethyl 4-methyl-2-(3-methylbenzofuran-2-carboxamido)thiazole-5-carboxylate
CAS 378764-56-8C17H16N2O4S
N,N,4-trimethyl-2-[(3-methyl-1-benzofuran-2-carbonyl)amino]-1,3-thiazole-5-carboxamide chemical structure, C17H17N3O3S, CAS 717866-61-0
N,N,4-trimethyl-2-[(3-methyl-1-benzofuran-2-carbonyl)amino]-1,3-thiazole-5-carboxamide
CAS 717866-61-0C17H17N3O3S
N-(4-tert-Butyl-1,3-thiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide chemical structure, C17H18N2O2S, CAS 717870-15-0
N-(4-tert-Butyl-1,3-thiazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide
CAS 717870-15-0C17H18N2O2S
Allyl 4-methyl-2-(3-methylbenzofuran-2-carboxamido)thiazole-5-carboxylate chemical structure, C18H16N2O4S, CAS 380573-56-8
Allyl 4-methyl-2-(3-methylbenzofuran-2-carboxamido)thiazole-5-carboxylate
CAS 380573-56-8C18H16N2O4S
5-Bromo-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C13H9BrN2O2S, CAS 775316-92-2
5-Bromo-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 775316-92-2C13H9BrN2O2S
Ethyl 2-(benzofuran-2-carboxamido)thiazole-4-carboxylate chemical structure, C15H12N2O4S, CAS 325746-49-4
Ethyl 2-(benzofuran-2-carboxamido)thiazole-4-carboxylate
CAS 325746-49-4C15H12N2O4S
Ethyl 2-(2-(benzofuran-2-carboxamido)thiazol-4-yl)acetate chemical structure, C16H14N2O4S, CAS 778622-74-5
Ethyl 2-(2-(benzofuran-2-carboxamido)thiazol-4-yl)acetate
CAS 778622-74-5C16H14N2O4S
3-(Propan-2-yloxymethyl)-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C16H16N2O3S, CAS 851686-22-1
3-(Propan-2-yloxymethyl)-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 851686-22-1C16H16N2O3S
N-(5-Methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C13H10N2O2S, CAS 877937-92-3
N-(5-Methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 877937-92-3C13H10N2O2S
5-Methoxy-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H12N2O3S, CAS 879309-44-1
5-Methoxy-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 879309-44-1C14H12N2O3S
3-Methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C13H10N2O2S, CAS 876720-93-3
3-Methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 876720-93-3C13H10N2O2S
5-Chloro-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C12H7ClN2O2S, CAS 882331-33-1
5-Chloro-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 882331-33-1C12H7ClN2O2S
5-Fluoro-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C13H9FN2O2S, CAS 875618-11-4
5-Fluoro-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 875618-11-4C13H9FN2O2S
3,5-Dimethyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H12N2O2S, CAS 895817-61-5
3,5-Dimethyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 895817-61-5C14H12N2O2S
7-Ethoxy-N-(thiazol-2-yl)benzofuran-2-carboxamide chemical structure, C14H12N2O3S, CAS 921801-55-0
7-Ethoxy-N-(thiazol-2-yl)benzofuran-2-carboxamide
CAS 921801-55-0C14H12N2O3S
2-(Benzofuran-2-carboxamido)-N-methylthiazole-4-carboxamide chemical structure, C14H11N3O3S, CAS 941882-15-1
2-(Benzofuran-2-carboxamido)-N-methylthiazole-4-carboxamide
CAS 941882-15-1C14H11N3O3S
2-(Benzofuran-2-carboxamido)-N-ethylthiazole-4-carboxamide chemical structure, C15H13N3O3S, CAS 941929-39-1
2-(Benzofuran-2-carboxamido)-N-ethylthiazole-4-carboxamide
CAS 941929-39-1C15H13N3O3S
7-Methoxy-N-(4-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H12N2O3S, CAS 951999-57-8
7-Methoxy-N-(4-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 951999-57-8C14H12N2O3S
7-Methoxy-N-(5-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C14H12N2O3S, CAS 951945-76-9
7-Methoxy-N-(5-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 951945-76-9C14H12N2O3S
7-Methoxy-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide chemical structure, C13H10N2O3S, CAS 921873-80-5
7-Methoxy-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide
CAS 921873-80-5C13H10N2O3S