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Murcko scaffold

4(3H)-Quinazolinone, 5,6,7,8-tetrahydro- scaffold

69 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
69
With full pages
13
Scaffold SMILES

O=c1[nH]cnc2c1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4(3H)-Quinazolinone, 5,6,7,8-tetrahydro- page
Murcko scaffold O=c1[nH]cnc2c1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

2-(Methylsulfanyl)-3-(prop-2-en-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C12H16N2OS, CAS 85458-81-7
2-(Methylsulfanyl)-3-(prop-2-en-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 85458-81-7C12H16N2OS
2,3-Diamino-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C8H12N4O, CAS 95095-60-6
2,3-Diamino-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 95095-60-6C8H12N4O
2-(4-Oxo-5,6,7,8-tetrahydroquinazolin-3-yl)acetic acid chemical structure, C10H12N2O3, CAS 1216081-35-4
2-(4-Oxo-5,6,7,8-tetrahydroquinazolin-3-yl)acetic acid
CAS 1216081-35-4C10H12N2O3
2-Amino-3-(prop-2-yn-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C11H13N3O, CAS 3441-94-9
2-Amino-3-(prop-2-yn-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 3441-94-9C11H13N3O
2-(2-Methyl-4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)acetic acid chemical structure, C11H14N2O3, CAS 1555883-08-3
2-(2-Methyl-4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)acetic acid
CAS 1555883-08-3C11H14N2O3
3-Methyl-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C9H12N2O, CAS 16064-20-3
3-Methyl-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 16064-20-3C9H12N2O
3-(Prop-2-yn-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C11H12N2O, CAS 881-06-1
3-(Prop-2-yn-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 881-06-1C11H12N2O
2-Amino-4-oxo-3,4,5,6,7,8-hexahydroquinazoline-6-carboxamide chemical structure, C9H12N4O2, CAS 5444-99-5
2-Amino-4-oxo-3,4,5,6,7,8-hexahydroquinazoline-6-carboxamide
CAS 5444-99-5C9H12N4O2
2-Amino-4-oxo-3,4,5,6,7,8-hexahydroquinazoline-6-carboxylic acid chemical structure, C9H11N3O3, CAS 5429-55-0
2-Amino-4-oxo-3,4,5,6,7,8-hexahydroquinazoline-6-carboxylic acid
CAS 5429-55-0C9H11N3O3
2-Amino-n,n-diethyl-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carboxamide chemical structure, C13H20N4O2, CAS 5437-51-4
2-Amino-n,n-diethyl-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carboxamide
CAS 5437-51-4C13H20N4O2
Methyl 2-(methylsulfanyl)-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carboxylate chemical structure, C11H14N2O3S, CAS 5437-53-6
Methyl 2-(methylsulfanyl)-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carboxylate
CAS 5437-53-6C11H14N2O3S
2-Chloro-3,4,5,6,7,8-hexahydroquinazolin-4-one chemical structure, C8H9ClN2O, CAS 178308-51-5
2-Chloro-3,4,5,6,7,8-hexahydroquinazolin-4-one
CAS 178308-51-5C8H9ClN2O
2,6-Diamino-5,6,7,8-tetrahydro-3H-quinazolin-4-one, hydrochloride chemical structure, C8H13ClN4O, CAS 5457-04-5
2,6-Diamino-5,6,7,8-tetrahydro-3H-quinazolin-4-one, hydrochloride
CAS 5457-04-5C8H13ClN4O
2,6-Diamino-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C8H12N4O, CAS 102077-48-5
2,6-Diamino-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 102077-48-5C8H12N4O
2-(Isopropylsulfanyl)-5,6,7,8-tetrahydro-4-quinazolinol chemical structure, C11H16N2OS, CAS 341967-88-2
2-(Isopropylsulfanyl)-5,6,7,8-tetrahydro-4-quinazolinol
CAS 341967-88-2C11H16N2OS
Butyl 2-amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carboxylate chemical structure, C13H19N3O3, CAS 5446-29-7
Butyl 2-amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carboxylate
CAS 5446-29-7C13H19N3O3
2-Amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carbohydrazide chemical structure, C9H13N5O2, CAS 5446-30-0
2-Amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carbohydrazide
CAS 5446-30-0C9H13N5O2
4(3H)-Quinazolinone, 5,6,7,8-tetrahydro-2-methyl- chemical structure, C9H12N2O, CAS 19178-21-3
4(3H)-Quinazolinone, 5,6,7,8-tetrahydro-2-methyl-
CAS 19178-21-3C9H12N2O
s-Ethyl 2-amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carbothioate chemical structure, C11H15N3O2S, CAS 5460-56-0
s-Ethyl 2-amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carbothioate
CAS 5460-56-0C11H15N3O2S
2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4-ol chemical structure, C9H13N3O2, CAS 5452-19-7
2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4-ol
CAS 5452-19-7C9H13N3O2
2-(Methylthio)-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C9H12N2OS, CAS 34170-21-3
2-(Methylthio)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 34170-21-3C9H12N2OS
2-Methyl-N-(4-oxo-3,4,5,6,7,8-hexahydro-2-quinazolinyl)propanamide chemical structure, C12H17N3O2, CAS 338416-47-0
2-Methyl-N-(4-oxo-3,4,5,6,7,8-hexahydro-2-quinazolinyl)propanamide
CAS 338416-47-0C12H17N3O2
2,2-Dimethyl-N-(4-oxo-3,4,5,6,7,8-hexahydro-2-quinazolinyl)propanamide chemical structure, C13H19N3O2, CAS 338416-64-1
2,2-Dimethyl-N-(4-oxo-3,4,5,6,7,8-hexahydro-2-quinazolinyl)propanamide
CAS 338416-64-1C13H19N3O2
2-(Chloromethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one chemical structure, C9H11ClN2O, CAS 145475-35-0
2-(Chloromethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS 145475-35-0C9H11ClN2O