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Murcko scaffold

4-(1H-Pyrazol-4-yl)-1,3-thiazole scaffold

34 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
34
With full pages
5
Scaffold SMILES

c1nc(-c2cn[nH]c2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1H-Pyrazol-4-yl)-1,3-thiazole page
Murcko scaffold c1nc(-c2cn[nH]c2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

4-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-thiazol-2-ylamine chemical structure, C9H12N4S, CAS 957301-85-8
4-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-thiazol-2-ylamine
CAS 957301-85-8C9H12N4S
4-(1,5-Dimethyl-1H-pyrazol-4-yl)-thiazol-2-ylamine chemical structure, C8H10N4S, CAS 957242-02-3
4-(1,5-Dimethyl-1H-pyrazol-4-yl)-thiazol-2-ylamine
CAS 957242-02-3C8H10N4S
4-(1-Ethyl-1H-pyrazol-4-yl)-thiazol-2-ylamine chemical structure, C8H10N4S, CAS 956363-87-4
4-(1-Ethyl-1H-pyrazol-4-yl)-thiazol-2-ylamine
CAS 956363-87-4C8H10N4S
4-(1-Methyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine chemical structure, C7H8N4S, CAS 957242-34-1
4-(1-Methyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS 957242-34-1C7H8N4S
4-(1,3-Dimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine chemical structure, C8H10N4S, CAS 956364-00-4
4-(1,3-Dimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS 956364-00-4C8H10N4S
4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine chemical structure, C9H12N4S, CAS 956364-01-5
4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS 956364-01-5C9H12N4S
4-(Trimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine chemical structure, C9H12N4S, CAS 1006483-60-8
4-(Trimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS 1006483-60-8C9H12N4S
4-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine chemical structure, C10H14N4S, CAS 1006483-62-0
4-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS 1006483-62-0C10H14N4S
Ethyl 4-(1-methyl-1H-pyrazol-4-yl)thiazole-2-carboxylate chemical structure, C10H11N3O2S, CAS 1248711-49-0
Ethyl 4-(1-methyl-1H-pyrazol-4-yl)thiazole-2-carboxylate
CAS 1248711-49-0C10H11N3O2S
(4-(1-Methyl-1H-pyrazol-4-yl)thiazol-2-yl)methanol chemical structure, C8H9N3OS, CAS 1339761-12-4
(4-(1-Methyl-1H-pyrazol-4-yl)thiazol-2-yl)methanol
CAS 1339761-12-4C8H9N3OS
2-Thiazolecarboxaldehyde, 4-(1-ethyl-1H-pyrazol-4-yl)- chemical structure, C9H9N3OS, CAS 1343204-59-0
2-Thiazolecarboxaldehyde, 4-(1-ethyl-1H-pyrazol-4-yl)-
CAS 1343204-59-0C9H9N3OS
4-(1-Methyl-1H-pyrazol-4-yl)-1,3-thiazole-2-carbaldehyde chemical structure, C8H7N3OS, CAS 1339381-50-8
4-(1-Methyl-1H-pyrazol-4-yl)-1,3-thiazole-2-carbaldehyde
CAS 1339381-50-8C8H7N3OS
2-Bromo-4-(1H-pyrazol-4-yl)-1,3-thiazole chemical structure, C6H4BrN3S, CAS 1368053-59-1
2-Bromo-4-(1H-pyrazol-4-yl)-1,3-thiazole
CAS 1368053-59-1C6H4BrN3S
2-Bromo-4-(1-methyl-4-pyrazolyl)thiazole chemical structure, C7H6BrN3S, CAS 1566421-29-1
2-Bromo-4-(1-methyl-4-pyrazolyl)thiazole
CAS 1566421-29-1C7H6BrN3S
2-Bromo-4-(1-ethyl-4-pyrazolyl)thiazole chemical structure, C8H8BrN3S, CAS 1564471-77-7
2-Bromo-4-(1-ethyl-4-pyrazolyl)thiazole
CAS 1564471-77-7C8H8BrN3S
4-(1H-Pyrazol-4-yl)-1,3-thiazole chemical structure, C6H5N3S, CAS 1927873-92-4
4-(1H-Pyrazol-4-yl)-1,3-thiazole
CAS 1927873-92-4C6H5N3S
2-(Methoxymethyl)-4-(1H-pyrazol-4-yl)-1,3-thiazole chemical structure, C8H9N3OS, CAS 2228387-51-5
2-(Methoxymethyl)-4-(1H-pyrazol-4-yl)-1,3-thiazole
CAS 2228387-51-5C8H9N3OS
2-Methyl-4-(1H-pyrazol-4-yl)-1,3-thiazole chemical structure, C7H7N3S, CAS 2228597-88-2
2-Methyl-4-(1H-pyrazol-4-yl)-1,3-thiazole
CAS 2228597-88-2C7H7N3S
4-[3,5-Dimethyl-1-(propan-2-yl)-1H-pyrazol-4-yl]-1,3-thiazol-2-amine chemical structure, C11H16N4S, CAS 2229369-94-0
4-[3,5-Dimethyl-1-(propan-2-yl)-1H-pyrazol-4-yl]-1,3-thiazol-2-amine
CAS 2229369-94-0C11H16N4S
4-[1-(Propan-2-yl)-1H-pyrazol-4-yl]-1,3-thiazol-2-amine chemical structure, C9H12N4S, CAS 2228449-31-6
4-[1-(Propan-2-yl)-1H-pyrazol-4-yl]-1,3-thiazol-2-amine
CAS 2228449-31-6C9H12N4S
4-[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1,3-thiazol-2-amine chemical structure, C8H7F3N4S, CAS 2229398-24-5
4-[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-1,3-thiazol-2-amine
CAS 2229398-24-5C8H7F3N4S
Methyl 4-(2-amino-1,3-thiazol-4-yl)-1-methyl-1H-pyrazole-3-carboxylate chemical structure, C9H10N4O2S, CAS 2229272-60-8
Methyl 4-(2-amino-1,3-thiazol-4-yl)-1-methyl-1H-pyrazole-3-carboxylate
CAS 2229272-60-8C9H10N4O2S
4-(5-Methoxy-1,3-dimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine chemical structure, C9H12N4OS, CAS 2229405-67-6
4-(5-Methoxy-1,3-dimethyl-1H-pyrazol-4-yl)-1,3-thiazol-2-amine
CAS 2229405-67-6C9H12N4OS
2-(Propan-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazole chemical structure, C9H11N3S, CAS 2228369-95-5
2-(Propan-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazole
CAS 2228369-95-5C9H11N3S