Murcko scaffold
Benzamide, N-2-thienyl- scaffold
930 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 930
- With full pages
- 52
Scaffold SMILES
O=C(Nc1cccs1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 673 to 720 of 930 chemicals
2-(2-Iodobenzamido)thiophene-3-carboxamide
CAS 864941-07-1C12H9IN2O2S
![2-[[4-[Butyl(methyl)sulfamoyl]benzoyl]amino]thiophene-3-carboxamide chemical structure, C17H21N3O4S2, CAS 864941-09-3](/s/NDCYNMROTZEGBX-UHFFFAOYSA-N.svg)
2-[[4-[Butyl(methyl)sulfamoyl]benzoyl]amino]thiophene-3-carboxamide
CAS 864941-09-3C17H21N3O4S2
2-(3,5-Dichlorobenzamido)thiophene-3-carboxamide
CAS 896680-77-6C12H8Cl2N2O2S
2-(3-Fluorobenzamido)-N-methylthiophene-3-carboxamide
CAS 864941-40-2C13H11FN2O2S
2-(4-Bromobenzamido)-N-methylthiophene-3-carboxamide
CAS 896680-79-8C13H11BrN2O2S
2-(2-Bromobenzamido)-N-methylthiophene-3-carboxamide
CAS 864941-41-3C13H11BrN2O2S
2-(4-Cyanobenzamido)-N-methylthiophene-3-carboxamide
CAS 864974-60-7C14H11N3O2S
2-(4-Ethoxybenzamido)-N-methylthiophene-3-carboxamide
CAS 897616-13-6C15H16N2O3S
2-(2-Chlorobenzamido)-N-methylthiophene-3-carboxamide
CAS 864974-81-2C13H11ClN2O2S
2-(2,4-Dichlorobenzamido)-N-methylthiophene-3-carboxamide
CAS 864974-83-4C13H10Cl2N2O2S
2-(2,5-Dichlorobenzamido)-N-methylthiophene-3-carboxamide
CAS 864974-85-6C13H10Cl2N2O2S
N-(3-Cyanothiophen-2-yl)-4-(dipropylsulfamoyl)benzamide
CAS 897615-86-0C18H21N3O3S2
N-(3-Cyanothiophen-2-yl)-3,4-dimethoxybenzamide
CAS 897615-87-1C14H12N2O3S
Methyl 2-(4-bromobenzamido)thiophene-3-carboxylate
CAS 921140-49-0C13H10BrNO3S
Methyl 2-(3,4-dimethylbenzamido)thiophene-3-carboxylate
CAS 920431-35-2C15H15NO3S
2-(4-Fluorobenzamido)thiophene-3-carboxamide
CAS 921055-16-5C12H9FN2O2S
2-(3-Bromobenzamido)thiophene-3-carboxamide
CAS 941976-36-9C12H9BrN2O2S
2-(2-Bromobenzamido)thiophene-3-carboxamide
CAS 942011-14-5C12H9BrN2O2S
2-(4-Methoxybenzamido)thiophene-3-carboxamide
CAS 60442-50-4C13H12N2O3S
2-(3,5-Dimethoxybenzamido)thiophene-3-carboxamide
CAS 924104-96-1C14H14N2O4S
2-(4-Butoxybenzamido)thiophene-3-carboxamide
CAS 941976-39-2C16H18N2O3S
2-(3-Butoxybenzamido)thiophene-3-carboxamide
CAS 942011-18-9C16H18N2O3S
2-(4-Ethoxybenzamido)thiophene-3-carboxamide
CAS 920477-87-8C14H14N2O3S
2-(2,4-Dichlorobenzamido)thiophene-3-carboxamide
CAS 941916-49-0C12H8Cl2N2O2S
- 2-(2,5-Dichlorobenzamido)thiophene-3-carboxamide941871-22-3C12H8Cl2N2O2S
- N-Methyl-2-(3-nitrobenzamido)thiophene-3-carboxamide941976-45-0C13H11N3O4S
- 2-(3-Bromobenzamido)-N-methylthiophene-3-carboxamide941871-25-6C13H11BrN2O2S
- 2-(3,5-Dimethoxybenzamido)-N-methylthiophene-3-carboxamide942011-26-9C15H16N2O4S
- N-Methyl-2-(3,4,5-trimethoxybenzamido)thiophene-3-carboxamide941976-48-3C16H18N2O5S
- 2-(4-Butoxybenzamido)-N-methylthiophene-3-carboxamide941916-55-8C17H20N2O3S
- 2-(4-(N,N-Dimethylsulfamoyl)benzamido)-N-methylthiophene-3-carboxamide888413-28-3C15H17N3O4S2
- 2-[[4-(Dipropylsulfamoyl)benzoyl]amino]-N-methylthiophene-3-carboxamide920435-81-0C19H25N3O4S2
- N-Methyl-2-(3-(trifluoromethyl)benzamido)thiophene-3-carboxamide942011-30-5C14H11F3N2O2S
- 2-(4-(N-Butyl-N-methylsulfamoyl)benzamido)-N-methylthiophene-3-carboxamide941916-61-6C18H23N3O4S2
- 2-{4-[Butyl(ethyl)sulfamoyl]benzamido}-N-methylthiophene-3-carboxamide920436-36-8C19H25N3O4S2
- N-(3-Cyano-4,5-dimethylthiophen-2-yl)-4-(dimethylamino)benzamide896304-25-9C16H17N3OS
- 4-[Bis(2-methylpropyl)sulfamoyl]-N-(3-cyanothiophen-2-yl)benzamide941892-40-6C20H25N3O3S2
- N-(3-Cyanothiophen-2-yl)-2,3-dimethoxybenzamide896011-73-7C14H12N2O3S
- 2-(2,3-Dimethoxybenzamido)-N-methylthiophene-3-carboxamide896011-78-2C15H16N2O4S
- N-(3-Cyanothiophen-2-yl)-2-(methylthio)benzamide896351-23-8C13H10N2OS2
- N-Methyl-2-(2-(methylthio)benzamido)thiophene-3-carboxamide896351-58-9C14H14N2O2S2
- Ethyl 3-methyl-5-(3-(methylthio)benzamido)thiophene-2-carboxylate896339-74-5C16H17NO3S2
- N-(3-Cyanothiophen-2-yl)-3-methylsulfanylbenzamide896343-64-9C13H10N2OS2
- 2-(3-(Methylthio)benzamido)thiophene-3-carboxamide896344-04-0C13H12N2O2S2
- N-Methyl-2-(3-(methylthio)benzamido)thiophene-3-carboxamide896344-12-0C14H14N2O2S2
- Ethyl 3-methyl-5-(4-(methylthio)benzamido)thiophene-2-carboxylate896353-79-0C16H17NO3S2
- N-(3-Cyanothiophen-2-yl)-4-(methylthio)benzamide896357-08-7C13H10N2OS2
- N-Methyl-2-(4-(methylthio)benzamido)thiophene-3-carboxamide896357-49-6C14H14N2O2S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals
O=C(Nc1ccccc1)C1CCCC143 chemicals