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Murcko scaffold

Benzamide, N-2-thienyl- scaffold

930 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
930
With full pages
52
Scaffold SMILES

O=C(Nc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Benzamide, N-2-thienyl- page
Murcko scaffold O=C(Nc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 625 to 672 of 930 chemicals

2-(2-Nitrobenzamido)thiophene-3-carboxamide chemical structure, C12H9N3O4S, CAS 864941-01-5
2-(2-Nitrobenzamido)thiophene-3-carboxamide
CAS 864941-01-5C12H9N3O4S
Ethyl 4-ethyl-5-methyl-2-[(2-methylbenzoyl)amino]-3-thiophenecarboxylate chemical structure, C18H21NO3S, CAS 544701-16-8
Ethyl 4-ethyl-5-methyl-2-[(2-methylbenzoyl)amino]-3-thiophenecarboxylate
CAS 544701-16-8C18H21NO3S
Propyl 2-[(4-chloro-2-nitrobenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate chemical structure, C17H17ClN2O5S, CAS 445006-23-5
Propyl 2-[(4-chloro-2-nitrobenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate
CAS 445006-23-5C17H17ClN2O5S
5-[(3-Chlorobenzoyl)amino]-2-N,2-N-diethyl-3-methylthiophene-2,4-dicarboxamide chemical structure, C18H20ClN3O3S, CAS 362680-25-9
5-[(3-Chlorobenzoyl)amino]-2-N,2-N-diethyl-3-methylthiophene-2,4-dicarboxamide
CAS 362680-25-9C18H20ClN3O3S
Ethyl 2-(3-bromobenzamido)-5-nitrothiophene-3-carboxylate chemical structure, C14H11BrN2O5S, CAS 477490-74-7
Ethyl 2-(3-bromobenzamido)-5-nitrothiophene-3-carboxylate
CAS 477490-74-7C14H11BrN2O5S
Ethyl 4-carbamoyl-5-{[(2,5-difluorophenyl)carbonyl]amino}-3-methylthiophene-2-carboxylate chemical structure, C16H14F2N2O4S, CAS 679814-82-5
Ethyl 4-carbamoyl-5-{[(2,5-difluorophenyl)carbonyl]amino}-3-methylthiophene-2-carboxylate
CAS 679814-82-5C16H14F2N2O4S
Methyl 4-carbamoyl-5-{[(3,5-difluorophenyl)carbonyl]amino}-3-methylthiophene-2-carboxylate chemical structure, C15H12F2N2O4S, CAS 680599-89-7
Methyl 4-carbamoyl-5-{[(3,5-difluorophenyl)carbonyl]amino}-3-methylthiophene-2-carboxylate
CAS 680599-89-7C15H12F2N2O4S
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-(trifluoromethyl)benzamide chemical structure, C15H11F3N2OS, CAS 752230-38-9
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3-(trifluoromethyl)benzamide
CAS 752230-38-9C15H11F3N2OS
2-(2-(Methylsulfonyl)benzamido)thiophene-3-carboxamide chemical structure, C13H12N2O4S2, CAS 848180-27-8
2-(2-(Methylsulfonyl)benzamido)thiophene-3-carboxamide
CAS 848180-27-8C13H12N2O4S2
2-(4-Isopropoxybenzamido)thiophene-3-carboxamide chemical structure, C15H16N2O3S, CAS 851619-54-0
2-(4-Isopropoxybenzamido)thiophene-3-carboxamide
CAS 851619-54-0C15H16N2O3S
2-[(4-Isobutoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide chemical structure, C18H22N2O3S, CAS 876362-09-3
2-[(4-Isobutoxybenzoyl)amino]-4,5-dimethyl-3-thiophenecarboxamide
CAS 876362-09-3C18H22N2O3S
2-(4-Isopropoxybenzamido)-4,5-dimethylthiophene-3-carboxamide chemical structure, C17H20N2O3S, CAS 383381-23-5
2-(4-Isopropoxybenzamido)-4,5-dimethylthiophene-3-carboxamide
CAS 383381-23-5C17H20N2O3S
2-(3-Butoxybenzamido)-4,5-dimethylthiophene-3-carboxamide chemical structure, C18H22N2O3S, CAS 881629-79-4
2-(3-Butoxybenzamido)-4,5-dimethylthiophene-3-carboxamide
CAS 881629-79-4C18H22N2O3S
2-[(3-Ethoxybenzoyl)amino]-4,5-dimethylthiophene-3-carboxamide chemical structure, C16H18N2O3S, CAS 881753-62-4
2-[(3-Ethoxybenzoyl)amino]-4,5-dimethylthiophene-3-carboxamide
CAS 881753-62-4C16H18N2O3S
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3,4,5-trimethoxybenzamide chemical structure, C17H18N2O4S, CAS 544450-67-1
N-(3-Cyano-4,5-dimethylthiophen-2-yl)-3,4,5-trimethoxybenzamide
CAS 544450-67-1C17H18N2O4S
Diethyl 3-methyl-5-[(3,4,5-triethoxybenzoyl)amino]-2,4-thiophenedicarboxylate chemical structure, C24H31NO8S, CAS 352702-13-7
Diethyl 3-methyl-5-[(3,4,5-triethoxybenzoyl)amino]-2,4-thiophenedicarboxylate
CAS 352702-13-7C24H31NO8S
Diethyl 5-(2,5-dichlorobenzamido)-3-methylthiophene-2,4-dicarboxylate chemical structure, C18H17Cl2NO5S, CAS 476293-68-2
Diethyl 5-(2,5-dichlorobenzamido)-3-methylthiophene-2,4-dicarboxylate
CAS 476293-68-2C18H17Cl2NO5S
2-(4-(tert-Butyl)benzamido)thiophene-3-carboxamide chemical structure, C16H18N2O2S, CAS 864941-02-6
2-(4-(tert-Butyl)benzamido)thiophene-3-carboxamide
CAS 864941-02-6C16H18N2O2S
Ethyl 2-(4-(N,N-diisobutylsulfamoyl)benzamido)-4,5-dimethylthiophene-3-carboxylate chemical structure, C24H34N2O5S2, CAS 391867-02-0
Ethyl 2-(4-(N,N-diisobutylsulfamoyl)benzamido)-4,5-dimethylthiophene-3-carboxylate
CAS 391867-02-0C24H34N2O5S2
Ethyl 2-(2-bromobenzamido)-5-nitrothiophene-3-carboxylate chemical structure, C14H11BrN2O5S, CAS 477490-78-1
Ethyl 2-(2-bromobenzamido)-5-nitrothiophene-3-carboxylate
CAS 477490-78-1C14H11BrN2O5S
2-(4-Acetylbenzamido)thiophene-3-carboxamide chemical structure, C14H12N2O3S, CAS 864940-69-2
2-(4-Acetylbenzamido)thiophene-3-carboxamide
CAS 864940-69-2C14H12N2O3S
N-Methyl-2-(4-methylbenzamido)thiophene-3-carboxamide chemical structure, C14H14N2O2S, CAS 864941-36-6
N-Methyl-2-(4-methylbenzamido)thiophene-3-carboxamide
CAS 864941-36-6C14H14N2O2S
Methyl 2-(2-chlorobenzamido)thiophene-3-carboxylate chemical structure, C13H10ClNO3S, CAS 864940-40-9
Methyl 2-(2-chlorobenzamido)thiophene-3-carboxylate
CAS 864940-40-9C13H10ClNO3S
2-(2-Methoxybenzamido)-N-methylthiophene-3-carboxamide chemical structure, C14H14N2O3S, CAS 864974-71-0
2-(2-Methoxybenzamido)-N-methylthiophene-3-carboxamide
CAS 864974-71-0C14H14N2O3S